Transcriptional regulator, MarR family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A)

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Q5HKZ1 (Q5HKZ1_STAEQ) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 63. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Transcriptional regulator, MarR family EMBL AAW53014.1

Gene names

Ordered Locus Names:

SERP2196 EMBL AAW53014.1

Organism

Staphylococcus epidermidis (strain ATCC 35984 / RP62A) [Complete proteome] [HAMAP] EMBL AAW53014.1

Taxonomic identifier

Taxonomic lineage

Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcus ›

Protein attributes

Sequence length	146 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 2 HTH marR-type DNA-binding domains. RuleBase RU000702

Ontologies

Keywords
Biological process	Transcription Transcription regulation SAAS SAAS000835 RuleBase RU000702
Ligand	DNA-binding SAAS SAAS000835 RuleBase RU000702
Technical term	3D-structure PDB 4HBL Complete proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q5HKZ1 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 6440549D2E5EC4A0
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146

17,302

        10         20         30         40         50         60 
MKQEQMRLAN QLCFSAYNVS RLFAQFYEKK LKQFGITYSQ YLVLLTLWEE NPQTLNSIGR 

        70         80         90        100        110        120 
HLDLSSNTLT PLLKRLEQSG WVKRERQQSD KRQLIITLTD NGQQQQEAVF EAISSCLPQE 

       130        140 
FDTTEYDETK YVFEELEQTL KHLIEK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain." Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., Deboy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L., Beanan M., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J., Khouri H. Fraser C.M. J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35984 / RP62A.
[2]	"Oxidation-sensing Regulator AbfR Regulates Oxidative Stress Responses, Bacterial Aggregation, and Biofilm Formation in Staphylococcus epidermidis." Liu X., Sun X., Wu Y., Xie C., Zhang W., Wang D., Chen X., Qu D., Gan J., Chen H., Jiang H., Lan L., Yang C.G. J. Biol. Chem. 288:3739-3752(2013) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000029 Genomic DNA. Translation: AAW53014.1.

RefSeq

YP_189752.1. NC_002976.3.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4HBL	X-ray	2.50	A/B/C/D	1-146	[»]

ProteinModelPortal

ModBase

Protein-protein interaction databases

STRING

176279.SERP2196.

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

AAW53014; AAW53014; SERP2196.

GeneID

KEGG

PATRIC

19615296. VBIStaEpi130894_2137.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

HOGENOM

OMA

ProtClustDB

Enzyme and pathway databases

BioCyc

SEPI176279:GJJB-2273-MONOMER.

Family and domain databases

Gene3D

1.10.10.10. 1 hit.

InterPro

IPR000835. Tscrpt_reg_HTH_MarR-typ.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]

Pfam

PF01047. MarR. 1 hit.
[Graphical view]

PRINTS

PR00598. HTHMARR.

SMART

SM00347. HTH_MARR. 1 hit.
[Graphical view]

PROSITE

PS50995. HTH_MARR_2. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

Q5HKZ1_STAEQ

Accession

Primary (citable) accession number: Q5HKZ1

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info