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Q5HKJ4 (Q5HKJ4_STAEQ) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ornithine carbamoyltransferase 2 HAMAP MF_01109

Short name=OTCase 2 HAMAP MF_01109
EC=2.1.3.3 HAMAP MF_01109
Gene names
Name:arcB-2 EMBL AAW53148.1
Synonyms:argF2 HAMAP MF_01109
Ordered Locus Names:SERP2351
OrganismStaphylococcus epidermidis (strain ATCC 35984 / RP62A) [Complete proteome] [HAMAP] EMBL AAW53148.1
Taxonomic identifier176279 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesStaphylococcus

Protein attributes

Sequence length333 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. SAAS SAAS002292 HAMAP MF_01109

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3. HAMAP MF_01109

Subcellular location

Cytoplasm By similarity SAAS SAAS002292 HAMAP MF_01109.

Sequence similarities

Belongs to the ATCase/OTCase family. HAMAP MF_01109

Sequences

Sequence LengthMass (Da)Tools
Q5HKJ4 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 7CCF06839E678244

FASTA33337,552
        10         20         30         40         50         60 
MKNLRNRSFL TLLDFSRQEV EFLLTLSEDL KRAKYIGTEK PMLKNKNIAL LFEKDSTRTR 

        70         80         90        100        110        120 
CAFEVAAHDQ GAHVTYLGPT GSQMGKKETA KDTARVLGGM YDGIEYRGFS QRTVETLAQY 

       130        140        150        160        170        180 
SGVPVWNGLT DEDHPTQVLA DFLTAKEVLK KEYADINFTY VGDGRNNVAN ALMQGAAIMG 

       190        200        210        220        230        240 
MNFHLVCPKE LNPTEELLNR CERIATENGG NILITDDIDK GVKDSDVIYT DVWVSMGEPD 

       250        260        270        280        290        300 
EVWQERLKLL KPYQVNQALL EKTGNPNVIF EHCLPSFHNA ETKIGQQIYE KYGISEMEVT 

       310        320        330 
DDVFESKASV VFQEAENRMH TIKAVMVATL GEF 

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References

[1]"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. expand/collapse author list , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
J. Bacteriol. 187:2426-2438(2005) [PubMed: 15774886] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000029 Genomic DNA. Translation: AAW53148.1.
RefSeqYP_189899.1. NC_002976.3.

3D structure databases

ProteinModelPortalQ5HKJ4.
SMRQ5HKJ4. Positions 2-333.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5HKJ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000043310; EBSTAP00000041853; EBSTAG00000043308.
GeneID3240871.
GenomeReviewsGene locus SERP2351 in contig CP000029_GR.
KEGGser:SERP2351.
PATRIC19615591. VBIStaEpi130894_2283.
TIGRSERP2351.

Phylogenomic databases

eggNOGCOG0078.
GeneTreeEBGT00050000023906.
HOGENOMHBG579429.
OMADFRIFAP.
ProtClustDBPRK04284.

Enzyme and pathway databases

BioCycSEPI176279:SERP2351-MONOMER.

Family and domain databases

HAMAPMF_01109. OTCase.
[Tree]
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. Orn_carbamltrans.
[Graphical view]
KOK00611.
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMSSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMsTIGR00658. Orni_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5HKJ4_STAEQ
AccessionPrimary (citable) accession number: Q5HKJ4
Entry history
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)