SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5HKE8

- Q5HKE8_STAEQ

UniProt

Q5HKE8 - Q5HKE8_STAEQ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Accumulation associated protein
Gene
aap, SERP2398
Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi2035 – 20351ZincImported
Metal bindingi2037 – 20371ZincImported
Metal bindingi2091 – 20911Zinc; via tele nitrogenImported
Metal bindingi2165 – 21651ZincImported
Metal bindingi2219 – 22191ZincImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

Metal-bindingImported, ZincImported

Enzyme and pathway databases

BioCyciSEPI176279:GJJB-2476-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Accumulation associated proteinImported
Gene namesi
Name:aapImported
Ordered Locus Names:SERP2398Imported
OrganismiStaphylococcus epidermidis (strain ATCC 35984 / RP62A)Imported
Taxonomic identifieri176279 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000531: Chromosome

Subcellular locationi

Secretedcell wall; Peptidoglycan-anchor By similarity SAAS annotations

GO - Cellular componenti

  1. cell wall Source: UniProtKB-SubCell
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell wallUniRule annotation, Secreted

PTM / Processingi

Keywords - PTMi

Peptidoglycan-anchorUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi176279.SERP2398.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4FUMX-ray2.40A2017-2223[»]
4FUNX-ray2.31A2017-2223[»]
4FUOX-ray1.97A2017-2223[»]
4FUPX-ray2.51A/B2017-2223[»]
ProteinModelPortaliQ5HKE8.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG12793.
KOiK14195.
OMAiQSEPTKA.

Family and domain databases

InterProiIPR011098. G5_dom.
IPR019948. Gram-positive_anchor.
IPR019931. LPXTG_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF07501. G5. 13 hits.
PF00746. Gram_pos_anchor. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS51109. G5. 13 hits.
PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5HKE8-1 [UniParc]FASTAAdd to Basket

« Hide

MGKRRQGPIN KKVDFLPNKL NKYSIRKFTV GTASILLGST LIFGSSSHEA     50
KAAEEKQVDP ITQANQNDSS ERSLENTNQP TVNNEAPQMS STLQAEEGSN 100
AEAPQSEPTK AEEGGNAEAA QSEPTKAEEG GNAEAPQSEP TKAEEGGNAE 150
AAQSEPTKTE EGSNVKAAQS EPTKAEEGSN AEAPQSEPTK TEEGSNAKAA 200
QSEPTKAEEG GNAEAAQSEP TKTEEGSNAE APQSEPTKAE EGGNAEAPQS 250
EPTKTEEGGN AEAPNVPTIK ANSDNDTQTQ FSEAPTRNDL ARKEDIPAVS 300
KNEELQSSQP NTDSKIEPTT SEPVNLNYSS PFMSLLSMPA DSSSNNTKNT 350
IDIPPTTVKG RDNYDFYGRV DIESNPTDLN ATNLTRYNYG QPPGTTTAGA 400
VQFKNQVSFD KDFDFNIRVA NNRQSNTTGA DGWGFMFSKK DGDDFLKNGG 450
ILREKGTPSA AGFRIDTGYY NNDPLDKIQK QAGQGYRGYG TFVKNDSQGN 500
TSKVGSGTPS TDFLNYADNT TNDLDGKFHG QKLNNVNLKY NASNQTFTAT 550
YAGKTWTATL SELGLSPTDS YNFLVTSSQY GNGNSGTYAS GVMRADLDGA 600
TLTYTPKAVD GDPIISTKEI PFNKKREFDP NLAPGTEKVV QKGEPGIETT 650
TTPTYVNPNT GEKVGEGEPT EKITKQPVDE IVHYGGEEIK PGHKDEFDPN 700
APKGSQTTQP GKPGVKNPDT GEVVTPPVDD VTKYGPVDGD PITSTEEIPF 750
DKKREFNPDL KPGEERVKQK GEPGTKTITT PTTKNPLTGE KVGEGEPTEK 800
ITKQPVDEIT EYGGEEIKPG HKDEFDPNAP KGSQEDVPGK PGVKNPDTGE 850
VVTPPVDDVT KYGPVDGDPI TSTEEIPFDK KREFNPDLKP GEERVKQKGE 900
PGTKTITTPT TKNPLTGEKV GEGEPTEKVT KQPVDEITEY GGEEIKPGHK 950
DEFDPNAPKG SQEDVPGKPG VKNPDTGEVV TPPVDDVTKY GPVDGDPITS 1000
TEEIPFDKKR EFDPNLAPGT EKVVQKGEPG TKTITTPTTK NPLTGEKVGE 1050
GEPTEKVTKQ PVDEIVHYGG EEIKPGHKDE FDPNAPKGSQ EDVPGKPGVK 1100
NPDTGEVVTP PVDDVTKYGP VDGDPITSTE EIPFDKKREF DPNLAPGTEK 1150
VVQKGEPGTK TITTPTTKNP LTGEKVGEGE PTEKVTKQPV DEIVHYGGEE 1200
IKPGHKDEFD PNAPKGSQED VPGKPGVKNP DTGEVVTPPV DDVTKYGPVD 1250
GDPITSTEEI PFDKKREFNP DLKPGEERVK QKGEPGTKTI TTPTTKNPLT 1300
GEKVGEGEPT EKITKQPVDE ITEYGGEEIK PGHKDEFDPN APKGSQTTQP 1350
GKPGVKNPDT GEVVTPPVDD VTKYGPVDGD PITSTEEIPF DKKREFNPDL 1400
KPGEERVKQK GEPGTKTITT PTTKNPLTGE KVGEGEPTEK ITKQPVDEIT 1450
EYGGEEIKPG HKDEFDPNAP KGSQEDVPGK PGVKNPDTGE VVTPPVDDVT 1500
KYGPVDGDPI TSTEEIPFDK KREFNPDLKP GEERVKQKGE PGTKTITTPT 1550
TKNPLTGEKV GEGEPTEKIT KQPVDEITEY GGEEIKPGHK DEFDPNAPKG 1600
SQEDVPGKPG VKNPDTGEVV TPPVDDVTKY GPVDGDPITS TEEIPFDKKR 1650
EFDPNLAPGT EKVVQKGEPG TKTITTPTTK NPLTGEKVGE GEPTEKITKQ 1700
PVDEITEYGG EEIKPGHKDE FDPNAPKGSQ EDVPGKPGVK NPDTGEVVTP 1750
PVDDVTKYGP VDGDPITSTE EIPFDKKREF DPNLAPGTEK VVQKGEPGTK 1800
TITTPTTKNP LTGEKVGEGE PTEKITKQPV DEIVHYGGEE IKTGHKDEFD 1850
PNAPKGSQTT QPGKPGVKNP DTGEVVTPPV DDVTKYGPVD GDPITSTEEI 1900
PFDKKREFDP NLAPGTEKVV QKGEPGTKTI TTPTTKNPLT GEKVGEGEPT 1950
EKITKQPVDE IVHYGGEEIK PGHKDEFDPN APKGSQEDVP GKPGVKNPDT 2000
GEVVTPPVDD VTKYGPVDGD SITSTEEIPF DKKREFDPNL APGTEKVVQK 2050
GEPGTKTITT PTTKNPLTGE KVGEGEPTEK ITKQPVDEIV HYGGEQIPQG 2100
HKDEFDPNAP VDSKTEVPGK PGVKNPDTGE VVTPPVDDVT KYGPVDGDSI 2150
TSTEEIPFDK KREFDPNLAP GTEKVVQKGE PGTKTITTPT TKNPLTGEKV 2200
GEGKSTEKVT KQPVDEIVEY GPTKAEPGKP AEPGKPAEPG KPAEPGTPAE 2250
PGKPAEPGTP AEPGKPAEPG KPAEPGKPAE PGKPAEPGTP AEPGTPAEPG 2300
KPAEPGTPAE PGKPAEPGTP AEPGKPAESG KPVEPGTPAQ SGAPEQPNRS 2350
MHSTDNKNQL PDTGENRQAN EGTLVGSLLA IVGSLFIFGR RKKGNEK 2397
Length:2,397
Mass (Da):255,612
Last modified:February 15, 2005 - v1
Checksum:i577FB0A4E5DDE15E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000029 Genomic DNA. Translation: AAW53239.1.
RefSeqiYP_189945.1. NC_002976.3.

Genome annotation databases

EnsemblBacteriaiAAW53239; AAW53239; SERP2398.
GeneIDi3242404.
KEGGiser:SERP2398.
PATRICi19615683. VBIStaEpi130894_2329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000029 Genomic DNA. Translation: AAW53239.1 .
RefSeqi YP_189945.1. NC_002976.3.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4FUM X-ray 2.40 A 2017-2223 [» ]
4FUN X-ray 2.31 A 2017-2223 [» ]
4FUO X-ray 1.97 A 2017-2223 [» ]
4FUP X-ray 2.51 A/B 2017-2223 [» ]
ProteinModelPortali Q5HKE8.
ModBasei Search...

Protein-protein interaction databases

STRINGi 176279.SERP2398.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAW53239 ; AAW53239 ; SERP2398 .
GeneIDi 3242404.
KEGGi ser:SERP2398.
PATRICi 19615683. VBIStaEpi130894_2329.

Phylogenomic databases

eggNOGi NOG12793.
KOi K14195.
OMAi QSEPTKA.

Enzyme and pathway databases

BioCyci SEPI176279:GJJB-2476-MONOMER.

Family and domain databases

InterProi IPR011098. G5_dom.
IPR019948. Gram-positive_anchor.
IPR019931. LPXTG_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
Pfami PF07501. G5. 13 hits.
PF00746. Gram_pos_anchor. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS51109. G5. 13 hits.
PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
    Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., Deboy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L., Beanan M., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J., Khouri H.
    , Utterback T., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K., Hance I.R., Nelson K.E., Fraser C.M.
    J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35984 / RP62A.
  2. "Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms."
    Conrady D.G., Wilson J.J., Herr A.B.
    Proc. Natl. Acad. Sci. U.S.A. 110:E202-E211(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.97 ANGSTROMS) OF 2017-2223 IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ5HKE8_STAEQ
AccessioniPrimary (citable) accession number: Q5HKE8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

Similar proteinsi