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Q5HKE8 (Q5HKE8_STAEQ) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:aap EMBL AAW53239.1
Ordered Locus Names:SERP2398 EMBL AAW53239.1
OrganismStaphylococcus epidermidis (strain ATCC 35984 / RP62A) [Complete proteome] [HAMAP] EMBL AAW53239.1
Taxonomic identifier176279 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length2397 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secretedcell wall; Peptidoglycan-anchor By similarity SAAS SAAS019948.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding20351Zinc PDB 4FUO
Metal binding20371Zinc PDB 4FUM PDB 4FUN
Metal binding20911Zinc; via tele nitrogen PDB 4FUM PDB 4FUN PDB 4FUO PDB 4FUP
Metal binding21651Zinc PDB 4FUO PDB 4FUP
Metal binding22191Zinc PDB 4FUM PDB 4FUN PDB 4FUP

Sequences

Sequence LengthMass (Da)Tools
Q5HKE8 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 577FB0A4E5DDE15E

FASTA2,397255,612
        10         20         30         40         50         60 
MGKRRQGPIN KKVDFLPNKL NKYSIRKFTV GTASILLGST LIFGSSSHEA KAAEEKQVDP 

        70         80         90        100        110        120 
ITQANQNDSS ERSLENTNQP TVNNEAPQMS STLQAEEGSN AEAPQSEPTK AEEGGNAEAA 

       130        140        150        160        170        180 
QSEPTKAEEG GNAEAPQSEP TKAEEGGNAE AAQSEPTKTE EGSNVKAAQS EPTKAEEGSN 

       190        200        210        220        230        240 
AEAPQSEPTK TEEGSNAKAA QSEPTKAEEG GNAEAAQSEP TKTEEGSNAE APQSEPTKAE 

       250        260        270        280        290        300 
EGGNAEAPQS EPTKTEEGGN AEAPNVPTIK ANSDNDTQTQ FSEAPTRNDL ARKEDIPAVS 

       310        320        330        340        350        360 
KNEELQSSQP NTDSKIEPTT SEPVNLNYSS PFMSLLSMPA DSSSNNTKNT IDIPPTTVKG 

       370        380        390        400        410        420 
RDNYDFYGRV DIESNPTDLN ATNLTRYNYG QPPGTTTAGA VQFKNQVSFD KDFDFNIRVA 

       430        440        450        460        470        480 
NNRQSNTTGA DGWGFMFSKK DGDDFLKNGG ILREKGTPSA AGFRIDTGYY NNDPLDKIQK 

       490        500        510        520        530        540 
QAGQGYRGYG TFVKNDSQGN TSKVGSGTPS TDFLNYADNT TNDLDGKFHG QKLNNVNLKY 

       550        560        570        580        590        600 
NASNQTFTAT YAGKTWTATL SELGLSPTDS YNFLVTSSQY GNGNSGTYAS GVMRADLDGA 

       610        620        630        640        650        660 
TLTYTPKAVD GDPIISTKEI PFNKKREFDP NLAPGTEKVV QKGEPGIETT TTPTYVNPNT 

       670        680        690        700        710        720 
GEKVGEGEPT EKITKQPVDE IVHYGGEEIK PGHKDEFDPN APKGSQTTQP GKPGVKNPDT 

       730        740        750        760        770        780 
GEVVTPPVDD VTKYGPVDGD PITSTEEIPF DKKREFNPDL KPGEERVKQK GEPGTKTITT 

       790        800        810        820        830        840 
PTTKNPLTGE KVGEGEPTEK ITKQPVDEIT EYGGEEIKPG HKDEFDPNAP KGSQEDVPGK 

       850        860        870        880        890        900 
PGVKNPDTGE VVTPPVDDVT KYGPVDGDPI TSTEEIPFDK KREFNPDLKP GEERVKQKGE 

       910        920        930        940        950        960 
PGTKTITTPT TKNPLTGEKV GEGEPTEKVT KQPVDEITEY GGEEIKPGHK DEFDPNAPKG 

       970        980        990       1000       1010       1020 
SQEDVPGKPG VKNPDTGEVV TPPVDDVTKY GPVDGDPITS TEEIPFDKKR EFDPNLAPGT 

      1030       1040       1050       1060       1070       1080 
EKVVQKGEPG TKTITTPTTK NPLTGEKVGE GEPTEKVTKQ PVDEIVHYGG EEIKPGHKDE 

      1090       1100       1110       1120       1130       1140 
FDPNAPKGSQ EDVPGKPGVK NPDTGEVVTP PVDDVTKYGP VDGDPITSTE EIPFDKKREF 

      1150       1160       1170       1180       1190       1200 
DPNLAPGTEK VVQKGEPGTK TITTPTTKNP LTGEKVGEGE PTEKVTKQPV DEIVHYGGEE 

      1210       1220       1230       1240       1250       1260 
IKPGHKDEFD PNAPKGSQED VPGKPGVKNP DTGEVVTPPV DDVTKYGPVD GDPITSTEEI 

      1270       1280       1290       1300       1310       1320 
PFDKKREFNP DLKPGEERVK QKGEPGTKTI TTPTTKNPLT GEKVGEGEPT EKITKQPVDE 

      1330       1340       1350       1360       1370       1380 
ITEYGGEEIK PGHKDEFDPN APKGSQTTQP GKPGVKNPDT GEVVTPPVDD VTKYGPVDGD 

      1390       1400       1410       1420       1430       1440 
PITSTEEIPF DKKREFNPDL KPGEERVKQK GEPGTKTITT PTTKNPLTGE KVGEGEPTEK 

      1450       1460       1470       1480       1490       1500 
ITKQPVDEIT EYGGEEIKPG HKDEFDPNAP KGSQEDVPGK PGVKNPDTGE VVTPPVDDVT 

      1510       1520       1530       1540       1550       1560 
KYGPVDGDPI TSTEEIPFDK KREFNPDLKP GEERVKQKGE PGTKTITTPT TKNPLTGEKV 

      1570       1580       1590       1600       1610       1620 
GEGEPTEKIT KQPVDEITEY GGEEIKPGHK DEFDPNAPKG SQEDVPGKPG VKNPDTGEVV 

      1630       1640       1650       1660       1670       1680 
TPPVDDVTKY GPVDGDPITS TEEIPFDKKR EFDPNLAPGT EKVVQKGEPG TKTITTPTTK 

      1690       1700       1710       1720       1730       1740 
NPLTGEKVGE GEPTEKITKQ PVDEITEYGG EEIKPGHKDE FDPNAPKGSQ EDVPGKPGVK 

      1750       1760       1770       1780       1790       1800 
NPDTGEVVTP PVDDVTKYGP VDGDPITSTE EIPFDKKREF DPNLAPGTEK VVQKGEPGTK 

      1810       1820       1830       1840       1850       1860 
TITTPTTKNP LTGEKVGEGE PTEKITKQPV DEIVHYGGEE IKTGHKDEFD PNAPKGSQTT 

      1870       1880       1890       1900       1910       1920 
QPGKPGVKNP DTGEVVTPPV DDVTKYGPVD GDPITSTEEI PFDKKREFDP NLAPGTEKVV 

      1930       1940       1950       1960       1970       1980 
QKGEPGTKTI TTPTTKNPLT GEKVGEGEPT EKITKQPVDE IVHYGGEEIK PGHKDEFDPN 

      1990       2000       2010       2020       2030       2040 
APKGSQEDVP GKPGVKNPDT GEVVTPPVDD VTKYGPVDGD SITSTEEIPF DKKREFDPNL 

      2050       2060       2070       2080       2090       2100 
APGTEKVVQK GEPGTKTITT PTTKNPLTGE KVGEGEPTEK ITKQPVDEIV HYGGEQIPQG 

      2110       2120       2130       2140       2150       2160 
HKDEFDPNAP VDSKTEVPGK PGVKNPDTGE VVTPPVDDVT KYGPVDGDSI TSTEEIPFDK 

      2170       2180       2190       2200       2210       2220 
KREFDPNLAP GTEKVVQKGE PGTKTITTPT TKNPLTGEKV GEGKSTEKVT KQPVDEIVEY 

      2230       2240       2250       2260       2270       2280 
GPTKAEPGKP AEPGKPAEPG KPAEPGTPAE PGKPAEPGTP AEPGKPAEPG KPAEPGKPAE 

      2290       2300       2310       2320       2330       2340 
PGKPAEPGTP AEPGTPAEPG KPAEPGTPAE PGKPAEPGTP AEPGKPAESG KPVEPGTPAQ 

      2350       2360       2370       2380       2390 
SGAPEQPNRS MHSTDNKNQL PDTGENRQAN EGTLVGSLLA IVGSLFIFGR RKKGNEK 

« Hide

References

« Hide 'large scale' references
[1]"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., Deboy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L., Beanan M., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J., Khouri H. expand/collapse author list , Utterback T., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K., Hance I.R., Nelson K.E., Fraser C.M.
J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35984 / RP62A.
[2]"Structural basis for Zn2+-dependent intercellular adhesion in staphylococcal biofilms."
Conrady D.G., Wilson J.J., Herr A.B.
Proc. Natl. Acad. Sci. U.S.A. 110:E202-E211(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.97 ANGSTROMS) OF 2017-2223 IN COMPLEX WITH ZINC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000029 Genomic DNA. Translation: AAW53239.1.
RefSeqYP_189945.1. NC_002976.3.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4FUMX-ray2.40A2017-2223[»]
4FUNX-ray2.31A2017-2223[»]
4FUOX-ray1.97A2017-2223[»]
4FUPX-ray2.51A/B2017-2223[»]
ProteinModelPortalQ5HKE8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING176279.SERP2398.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW53239; AAW53239; SERP2398.
GeneID3242404.
KEGGser:SERP2398.
PATRIC19615683. VBIStaEpi130894_2329.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG12793.
KOK14195.
OMAQSEPTKA.

Enzyme and pathway databases

BioCycSEPI176279:GJJB-2476-MONOMER.

Family and domain databases

InterProIPR011098. G5_dom.
IPR005877. Gpos_YSIRK.
IPR019948. Gram-positive_anchor.
IPR019931. LPXTG_anchor.
[Graphical view]
PfamPF07501. G5. 13 hits.
PF00746. Gram_pos_anchor. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
TIGRFAMsTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEPS51109. G5. 13 hits.
PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5HKE8_STAEQ
AccessionPrimary (citable) accession number: Q5HKE8
Entry history
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)