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Q5HII8 (Q5HII8_STAAC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877
Gene names
Name:rsmI HAMAP MF_01877
Ordered Locus Names:SACOL0531
OrganismStaphylococcus aureus (strain COL) [Complete proteome] [HAMAP] EMBL AAW37650.1
Taxonomic identifier93062 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length279 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877

Subcellular location

Cytoplasm By similarity HAMAP MF_01877.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
   Biological processrRNA processing HAMAP MF_01877
   Cellular componentCytoplasm HAMAP MF_01877
   LigandS-adenosyl-L-methionine HAMAP MF_01877
   Molecular functionMethyltransferase HAMAP MF_01877 EMBL AAW37650.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processenzyme-directed rRNA 2'-O-methylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionrRNA (cytosine-2'-O-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q5HII8 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 322A75B31B97C4E6

FASTA27931,275
        10         20         30         40         50         60 
MAVLYLVGTP IGNLADITYR AVDVLKRVDM IACEDTRVTS KLCNHYDIPT PLKSYHEHNK 

        70         80         90        100        110        120 
DKQTAFIIEQ LELGLDVALV SDAGLPLISD PGYELVVAAR EANIKVETVP GPNAGLTALM 

       130        140        150        160        170        180 
ASGLPSYVYT FLGFLPRKEK EKSAVLEQRM HENSTLIIYE SPHRVTDTLK TIAKIDATRQ 

       190        200        210        220        230        240 
VSLGRELTKK FEQIVTDDVT QLQALIQQGD VPLKGEFVIL IEGAKANNEI SWFDDLSINE 

       250        260        270 
HVDHYIQTSQ MKPKQAIKKV AEERQLKTNE VYNIYHQIS

« Hide

References

[1]"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. expand/collapse author list , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
J. Bacteriol. 187:2426-2438(2005) [PubMed: 15774886] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000046 Genomic DNA. Translation: AAW37650.1.
RefSeqYP_185419.1. NC_002951.2.

3D structure databases

ProteinModelPortalQ5HII8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5HII8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000008862; EBSTAP00000008597; EBSTAG00000008861.
GeneID3237106.
GenomeReviewsGene locus SACOL0531 in contig CP000046_GR.
KEGGsac:SACOL0531.
PATRIC19527312. VBIStaAur112458_0518.
TIGRSACOL0531.

Phylogenomic databases

eggNOGCOG0313.
GeneTreeEBGT00050000024705.
HOGENOMHBG529058.
OMAGREMTKI.
PhylomeDBQ5HII8.
ProtClustDBCLSK884689.

Enzyme and pathway databases

BioCycSAUR93062:SACOL0531-MONOMER.

Family and domain databases

HAMAPMF_01877. 16SrRNA_methyltr_I.
[Tree]
InterProIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
Gene3DG3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
KOK07056.
PANTHERPTHR21091:SF18. PTHR21091:SF18. 1 hit.
PfamPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFPIRSF005917. MTase_YraL. 1 hit.
SUPFAMSSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMsTIGR00096. TIGR00096. 1 hit.
PROSITEPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5HII8_STAAC
AccessionPrimary (citable) accession number: Q5HII8
Entry history
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info