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Protein

DNA-directed RNA polymerase subunit beta'

Gene

rpoC

Organism
Staphylococcus aureus (strain COL)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciSAUR93062:GCEP-587-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit beta'UniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit beta'UniRule annotation
Alternative name(s):
RNA polymerase subunit beta'UniRule annotation
Transcriptase subunit beta'UniRule annotation
Gene namesi
Name:rpoCUniRule annotation
Ordered Locus Names:SACOL0589
OrganismiStaphylococcus aureus (strain COL)
Taxonomic identifieri93062 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000530 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12071207DNA-directed RNA polymerase subunit beta'PRO_0000067792Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi93062.SACOL0589.

Structurei

3D structure databases

ProteinModelPortaliQ5HID2.
SMRiQ5HID2. Positions 4-1193.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D27. Bacteria.
COG0086. LUCA.
HOGENOMiHOG000218387.
KOiK03046.
OMAiYFAAYMI.

Family and domain databases

HAMAPiMF_01322. RNApol_bact_RpoC. 1 hit.
InterProiIPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
PfamiPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 2 hits.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTiSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02386. rpoC_TIGR. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5HID2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDVNNFHYM KIGLASPEKI RSWSFGEVKK PETINYRTLK PEKDGLFCER
60 70 80 90 100
IFGPTKDWEC SCGKYKRVRY KGMVCDRCGV EVTKSKVRRE RMGHIELAAP
110 120 130 140 150
VSHIWYFKGI PSRMGLLLDM SPRALEEVIY FASYVVVDPG PTGLEKKTLL
160 170 180 190 200
SEAEFRDYYD KYPGQFVAKM GAEGIKDLLE EIDLDEELKL LRDELESATG
210 220 230 240 250
QRLTRAIKRL EVVESFRNSG NKPSWMILDV LPIIPPEIRP MVQLDGGRFA
260 270 280 290 300
TSDLNDLYRR VINRNNRLKR LLDLGAPGII VQNEKRMLQE AVDALIDNGR
310 320 330 340 350
RGRPVTGPGN RPLKSLSHML KGKQGRFRQN LLGKRVDYSG RSVIAVGPSL
360 370 380 390 400
KMYQCGLPKE MALELFKPFV MKELVQREIA TNIKNAKSKI ERMDDEVWDV
410 420 430 440 450
LEEVIREHPV LLNRAPTLHR LGIQAFEPTL VEGRAIRLHP LVTTAYNADF
460 470 480 490 500
DGDQMAVHVP LSKEAQAEAR MLMLAAQNIL NPKDGKPVVT PSQDMVLGNY
510 520 530 540 550
YLTLERKDAV NTGAIFNNTN EVLKAYANGF VHLHTRIGVH ASSFNNPTFT
560 570 580 590 600
EEQNKKILAT SVGKIIFNEI IPDSFAYINE PTQENLERKT PNRYFIDPTT
610 620 630 640 650
LGEGGLKEYF ENEELIEPFN KKFLGNIIAE VFNRFSITDT SMMLDRMKDL
660 670 680 690 700
GFKFSSKAGI TVGVADIVVL PDKQQILDEH EKLVDRITKQ FNRGLITEEE
710 720 730 740 750
RYNAVVEIWT DAKDQIQGEL MQSLDKTNPI FMMSDSGARG NASNFTQLAG
760 770 780 790 800
MRGLMAAPSG KIIELPITSS FREGLTVLEY FISTHGARKG LADTALKTAD
810 820 830 840 850
SGYLTRRLVD VAQDVIVREE DCGTDRGLLV SDIKEGTEMI EPFIERIEGR
860 870 880 890 900
YSKETIRHPE TDEIIIRPDE LITPEIAKKI TDAGIEQMYI RSAFTCNARH
910 920 930 940 950
GVCEKCYGKN LATGEKVEVG EAVGTIAAQS IGEPGTQLTM RTFHTGGVAG
960 970 980 990 1000
SDITQGLPRI QEIFEARNPK GQAVITEIEG VVEDIKLAKD RQQEIVVKGA
1010 1020 1030 1040 1050
NETRSYLASG TSRIIVEIGQ PVQRGEVLTE GSIEPKNYLS VAGLNATESY
1060 1070 1080 1090 1100
LLKEVQKVYR MQGVEIDDKH VEVMVRQMLR KVRIIEAGDT KLLPGSLVDI
1110 1120 1130 1140 1150
HNFTDANREA FKHRKRPATA KPVLLGITKA SLETESFLSA ASFQETTRVL
1160 1170 1180 1190 1200
TDAAIKGKRD DLLGLKENVI IGKLIPAGTG MRRYSDVKYE KTAKPVAEVE

SQTEVTE
Length:1,207
Mass (Da):135,409
Last modified:February 15, 2005 - v1
Checksum:i8E87587E6C454003
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA. Translation: AAW37699.1.
RefSeqiWP_000567961.1. NC_002951.2.

Genome annotation databases

EnsemblBacteriaiAAW37699; AAW37699; SACOL0589.
KEGGisac:SACOL0589.
PATRICi19527440. VBIStaAur112458_0573.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA. Translation: AAW37699.1.
RefSeqiWP_000567961.1. NC_002951.2.

3D structure databases

ProteinModelPortaliQ5HID2.
SMRiQ5HID2. Positions 4-1193.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93062.SACOL0589.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW37699; AAW37699; SACOL0589.
KEGGisac:SACOL0589.
PATRICi19527440. VBIStaAur112458_0573.

Phylogenomic databases

eggNOGiENOG4105D27. Bacteria.
COG0086. LUCA.
HOGENOMiHOG000218387.
KOiK03046.
OMAiYFAAYMI.

Enzyme and pathway databases

BioCyciSAUR93062:GCEP-587-MONOMER.

Family and domain databases

HAMAPiMF_01322. RNApol_bact_RpoC. 1 hit.
InterProiIPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
PfamiPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 2 hits.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTiSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02386. rpoC_TIGR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRPOC_STAAC
AccessioniPrimary (citable) accession number: Q5HID2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: February 15, 2005
Last modified: September 7, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.