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Q5HIB4

- SDRC_STAAC

UniProt

Q5HIB4 - SDRC_STAAC

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Protein

Serine-aspartate repeat-containing protein C

Gene

sdrC

Organism
Staphylococcus aureus (strain COL)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cell surface-associated protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes. May bind calcium (By similarity).By similarity

GO - Biological processi

  1. cell adhesion Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Calcium

Enzyme and pathway databases

BioCyciSAUR93062:GCEP-606-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine-aspartate repeat-containing protein C
Gene namesi
Name:sdrC
Ordered Locus Names:SACOL0608
OrganismiStaphylococcus aureus (strain COL)
Taxonomic identifieri93062 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000530: Chromosome

Subcellular locationi

Secretedcell wall PROSITE-ProRule annotation; Peptidoglycan-anchor PROSITE-ProRule annotation

GO - Cellular componenti

  1. cell wall Source: UniProtKB-KW
  2. extracellular region Source: UniProtKB-KW
  3. membrane Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 5050Sequence AnalysisAdd
BLAST
Chaini51 – 913863Serine-aspartate repeat-containing protein CPRO_0000281390Add
BLAST
Propeptidei914 – 94734Removed by sortasePROSITE-ProRule annotationPRO_0000281391Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei913 – 9131Pentaglycyl murein peptidoglycan amidated threoninePROSITE-ProRule annotation

Keywords - PTMi

Peptidoglycan-anchor

Interactioni

Protein-protein interaction databases

STRINGi93062.SACOL0608.

Structurei

3D structure databases

ProteinModelPortaliQ5HIB4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini496 – 606111CNA-B 1Add
BLAST
Domaini607 – 717111CNA-B 2Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni51 – 495445Ligand binding A regionAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi910 – 9145LPXTG sorting signalPROSITE-ProRule annotation

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi65 – 167103Thr-richAdd
BLAST
Compositional biasi718 – 887170Asp/Ser-richAdd
BLAST

Sequence similaritiesi

Contains 2 CNA-B domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000279832.
KOiK14194.
OMAiDNTSVKE.
OrthoDBiEOG6RNQ8T.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
2.60.40.1280. 1 hit.
2.60.40.1290. 1 hit.
InterProiIPR011266. Adhesin_Fg-bd_dom_2.
IPR008966. Adhesion_dom.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR011252. Fibrogen-bd_dom1.
IPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR019931. LPXTG_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view]
PfamiPF05738. Cna_B. 2 hits.
PF00746. Gram_pos_anchor. 1 hit.
PF10425. SdrG_C_C. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view]
SUPFAMiSSF49401. SSF49401. 2 hits.
TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5HIB4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNKKTATNR KGMIPNRLNK FSIRKYSVGT ASILVGTTLI FGLSGHEAKA
60 70 80 90 100
AEHTNGELNQ SKNETTAPSE NKTTKKVDSR QLKDNTQTAT ADQPKVTMSD
110 120 130 140 150
SATVKETSSN MQSPQNATAN QSTTKTSNVT TNDKSSTTYS NETDKSNLTQ
160 170 180 190 200
AKDVSTTPKT TTIKPRTLNR MAVNTVAAPQ QGTNVNDKVH FSNIDIAIDK
210 220 230 240 250
GHVNQTTGKT EFWATSSDVL KLKANYTIDD SVKEGDTFTF KYGQYFRPGS
260 270 280 290 300
VRLPSQTQNL YNAQGNIIAK GIYDSTTNTT TYTFTNYVDQ YTNVRGSFEQ
310 320 330 340 350
VAFAKRKNAT TDKTAYKMEV TLGNDTYSEE IIVDYGNKKA QPLISSTNYI
360 370 380 390 400
NNEDLSRNMT AYVNQPKNTY TKQTFVTNLT GYKFNPNAKN FKIYEVTDQN
410 420 430 440 450
QFVDSFTPDT SKLKDVTDQF DVIYSNDNKT ATVDLMKGQT SSNKQYIIQQ
460 470 480 490 500
VAYPDNSSTD NGKIDYTLDT DKTKYSWSNS YSNVNGSSTA NGDQKKYNLG
510 520 530 540 550
DYVWEDTNKD GKQDANEKGI KGVYVILKDS NGKELDRTTT DENGKYQFTG
560 570 580 590 600
LSNGTYSVEF STPAGYTPTT ANVGTDDAVD SDGLTTTGVI KDADNMTLDS
610 620 630 640 650
GFYKTPKYSL GDYVWYDSNK DGKQDSTEKG IKGVKVTLQN EKGEVIGTTE
660 670 680 690 700
TDENGKYRFD NLDSGKYKVI FEKPAGLTQT GTNTTEDDKD ADGGEVDVTI
710 720 730 740 750
TDHDDFTLDN GYYEEETSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS
760 770 780 790 800
DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS
810 820 830 840 850
DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS DSDSDSDSDS
860 870 880 890 900
DSDSDSDSDS DSDSDSDSDS DSDSDNDSDS DSDSDSDAGK HTPAKPMSTV
910 920 930 940
KDQHKTAKAL PETGSENNNS NNGTLFGGLF AALGSLLLFG RRKKQNK
Length:947
Mass (Da):102,916
Last modified:February 15, 2005 - v1
Checksum:i389C5E6432A97F5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA. Translation: AAW37717.1.
RefSeqiYP_185493.1. NC_002951.2.

Genome annotation databases

EnsemblBacteriaiAAW37717; AAW37717; SACOL0608.
GeneIDi3236353.
KEGGisac:SACOL0608.
PATRICi19527476. VBIStaAur112458_0591.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA. Translation: AAW37717.1 .
RefSeqi YP_185493.1. NC_002951.2.

3D structure databases

ProteinModelPortali Q5HIB4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 93062.SACOL0608.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAW37717 ; AAW37717 ; SACOL0608 .
GeneIDi 3236353.
KEGGi sac:SACOL0608.
PATRICi 19527476. VBIStaAur112458_0591.

Phylogenomic databases

eggNOGi NOG12793.
HOGENOMi HOG000279832.
KOi K14194.
OMAi DNTSVKE.
OrthoDBi EOG6RNQ8T.

Enzyme and pathway databases

BioCyci SAUR93062:GCEP-606-MONOMER.

Miscellaneous databases

PROi Q5HIB4.

Family and domain databases

Gene3Di 2.60.40.10. 2 hits.
2.60.40.1280. 1 hit.
2.60.40.1290. 1 hit.
InterProi IPR011266. Adhesin_Fg-bd_dom_2.
IPR008966. Adhesion_dom.
IPR008454. Collagen-bd_Cna-like_B-typ_dom.
IPR011252. Fibrogen-bd_dom1.
IPR019948. Gram-positive_anchor.
IPR013783. Ig-like_fold.
IPR019931. LPXTG_anchor.
IPR005877. YSIRK_signal_dom.
[Graphical view ]
Pfami PF05738. Cna_B. 2 hits.
PF00746. Gram_pos_anchor. 1 hit.
PF10425. SdrG_C_C. 1 hit.
PF04650. YSIRK_signal. 1 hit.
[Graphical view ]
SUPFAMi SSF49401. SSF49401. 2 hits.
TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
TIGR01168. YSIRK_signal. 1 hit.
PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
    Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H.
    , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
    J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: COL.

Entry informationi

Entry nameiSDRC_STAAC
AccessioniPrimary (citable) accession number: Q5HIB4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: February 15, 2005
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3