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Q5HH75 (Q5HH75_STAAC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Enoyl-[acyl-carrier-protein] reductase [NADPH] PIRNR PIRNR000094

Short name=ENR PIRNR PIRNR000094
EC=1.3.1.10 PIRNR PIRNR000094
Gene names
Name:fabI EMBL AAW36482.1
Ordered Locus Names:SACOL1016
OrganismStaphylococcus aureus (strain COL) [Complete proteome] [HAMAP] EMBL AAW36482.1
Taxonomic identifier93062 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesStaphylococcus

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acyl-[acyl-carrier-protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADPH. PIRNR PIRNR000094

Pathway

Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1571Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

Sequence LengthMass (Da)Tools
Q5HH75 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 69487F3F410B9A15

FASTA25627,992
        10         20         30         40         50         60 
MLNLENKTYV IMGIANKRSI AFGVAKVLDQ LGAKLVFTYR KERSRKELEK LLEQLNQPEA 

        70         80         90        100        110        120 
HLYQIDVQSD EEVINGFEQI GKDVGNIDGV YHSIAFANME DLRGRFSETS REGFLLAQDI 

       130        140        150        160        170        180 
SSYSLTIVAH EAKKLMPEGG SIVATTYLGG EFAVQNYNVM GVAKASLEAN VKYLALDLGP 

       190        200        210        220        230        240 
DNIRVNAISA GPIRTLSAKG VGGFNTILKE IEERAPLKRN VDQVEVGKTA AYLLSDLSSG 

       250 
VTGENIHVDS GFHAIK 

« Hide

References

[1]"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. expand/collapse author list , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
J. Bacteriol. 187:2426-2438(2005) [PubMed: 15774886] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000046 Genomic DNA. Translation: AAW36482.1.
RefSeqYP_185882.1. NC_002951.2.

3D structure databases

ProteinModelPortalQ5HH75.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5HH75.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000010896; EBSTAP00000010631; EBSTAG00000010895.
GeneID3237502.
GenomeReviewsGene locus SACOL1016 in contig CP000046_GR.
KEGGsac:SACOL1016.
PATRIC19528270. VBIStaAur112458_0990.
TIGRSACOL1016.

Phylogenomic databases

eggNOGCOG0623.
GeneTreeEBGT00050000023865.
HOGENOMHBG750976.
OMAKKWDGLD.
PhylomeDBQ5HH75.
ProtClustDBPRK08594.

Enzyme and pathway databases

BioCycSAUR93062:SACOL1016-MONOMER.

Family and domain databases

InterProIPR002198. DH_sc/Rdtase_SDR.
IPR014358. Enoyl-ACP_Rdtase_NADH.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00208.
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFPIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTSPR00081. GDHRDH.
ProtoNetSearch...

Entry information

Entry nameQ5HH75_STAAC
AccessionPrimary (citable) accession number: Q5HH75
Entry history
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)