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Protein

Serine protease HtrA-like

Gene

SACOL1028

Organism
Staphylococcus aureus (strain COL)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei504Charge relay systemSequence analysis1
Active sitei534Charge relay systemSequence analysis1
Active sitei619Charge relay systemSequence analysis1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Names & Taxonomyi

Protein namesi
Recommended name:
Serine protease HtrA-like (EC:3.4.21.-)
Gene namesi
Ordered Locus Names:SACOL1028
OrganismiStaphylococcus aureus (strain COL)
Taxonomic identifieri93062 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000530 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei410 – 430HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002524651 – 769Serine protease HtrA-likeAdd BLAST769

Proteomic databases

PRIDEiQ5HH63

Interactioni

Protein-protein interaction databases

STRINGi93062.SACOL1028

Structurei

3D structure databases

ProteinModelPortaliQ5HH63
SMRiQ5HH63
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini680 – 733PDZAdd BLAST54

Sequence similaritiesi

Belongs to the peptidase S1C family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C0H Bacteria
COG0265 LUCA
HOGENOMiHOG000279952
OMAiRNMAIND

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
IPR009003 Peptidase_S1_PA
IPR001940 Peptidase_S1C
PfamiView protein in Pfam
PF13180 PDZ_2, 1 hit
PRINTSiPR00834 PROTEASES2C
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
SSF50494 SSF50494, 1 hit

Sequencei

Sequence statusi: Complete.

Q5HH63-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIGKKHVIP KSQYRRKRRE FFHNEDREEN LNQHQDKQNI DNTTSKKADK
60 70 80 90 100
QIHKDSIDKH ERFKNSLSSH LEQRNRDVNE NKAEESKSNQ DSKSAYNRDH
110 120 130 140 150
YLTDDVSKKQ NSLDSVDQDT EKSKYYEQNS EATLSTKSTD KVESTEMRKL
160 170 180 190 200
SSDKNKVGHE EQHVLSKPSE HDKETRIDSE SSRTDSDSSM QTEKIKKDSS
210 220 230 240 250
DGNKSSNLKS EVISDKSNTV PKLSESDDEV NNQKPLTLPE EQKLKRQQSQ
260 270 280 290 300
NEQTKTYTYG DSEQNDKSNH ENDLSHHIPS ISDDKDNVMR ENHIVDDNPD
310 320 330 340 350
NDINTPSLSK TDDDRKLDEK IHVEDKHKQN ADSSETVGYQ SQSTASHRST
360 370 380 390 400
EKRNISINDH DKLNGQKTNT KTSANNNQKK ATSKLNKGRA TNNNYSDILK
410 420 430 440 450
KFWMMYWPKL VILMGIIILI VILNAIFNNV NKNDRMNDNN DADAQKYTTT
460 470 480 490 500
MKNANNTVKS VVTVENETSK DSSLPKDKAS QDEVGSGVVY KKSGDTLYIV
510 520 530 540 550
TNAHVVGDKE NQKITFSNNK SVVGKVLGKD KWSDLAVVKA TSSDSSVKEI
560 570 580 590 600
AIGDSNNLVL GEPILVVGNP LGVDFKGTVT EGIISGLNRN VPIDFDKDNK
610 620 630 640 650
YDMLMKAFQI DASVNPGNSG GAVVNREGKL IGVVAAKISM PNVENMSFAI
660 670 680 690 700
PVNEVQKIVK DLETKGKIDY PDVGVKMKNI ASLNSFERQA VKLPGKVKNG
710 720 730 740 750
VVVDQVDNNG LADQSGLKKG DVITELDGKL LEDDLRFRQI IFSHKDDLKS
760
ITAKIYRDGK EKEINIKLK
Length:769
Mass (Da):86,432
Last modified:February 15, 2005 - v1
Checksum:i7948E23EAD17CEBB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA Translation: AAW36494.1

Genome annotation databases

EnsemblBacteriaiAAW36494; AAW36494; SACOL1028
KEGGisac:SACOL1028

Similar proteinsi

Entry informationi

Entry nameiHTRAL_STAAC
AccessioniPrimary (citable) accession number: Q5HH63
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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