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Q5HGK3 (FABD_STAAC) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Malonyl CoA-acyl carrier protein transacylase

Short name=MCT
EC=2.3.1.39
Gene names
Name:fabD
Ordered Locus Names:SACOL1244
OrganismStaphylococcus aureus (strain COL) [Complete proteome] [HAMAP]
Taxonomic identifier93062 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length308 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Malonyl-CoA + [acyl-carrier-protein] = CoA + malonyl-[acyl-carrier-protein].

Pathway

Lipid metabolism; fatty acid biosynthesis.

Sequence similarities

Belongs to the FabD family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 308308Malonyl CoA-acyl carrier protein transacylase
PRO_0000194221

Sites

Active site891 By similarity
Active site1991 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5HGK3 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: C28AEC6CC50805C2

FASTA30833,635
        10         20         30         40         50         60 
MSKTAIIFPG QGAQKVGMAQ DLFNNNDQAT EILTSAANTL DFDILETMFT DEEGKLGETE 

        70         80         90        100        110        120 
NTQPALLTHS SALLAALKNL NPDFTMGHSL GEYSSLVAAD VLSFEDAVKI VRKRGQLMAQ 

       130        140        150        160        170        180 
AFPTGVGSMA AVLGLDFDKV DEICKSLSSD DKIIEPANIN CPGQIVVSGH KALIDELVEK 

       190        200        210        220        230        240 
GKSLGAKRVM PLAVSGPFHS SLMKVIEEDF SSYINQFEWR DAKFPVVQNV NAQGETDKEV 

       250        260        270        280        290        300 
IKSNMVKQLY SPVQFINSTE WLIDQGVDHF IEIGPGKVLS GLIKKINRDV KLTSIQTLED 


VKGWNEND 

« Hide

References

[1]"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. expand/collapse author list , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: COL.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000046 Genomic DNA. Translation: AAW38078.1.
RefSeqYP_186104.1. NC_002951.2.

3D structure databases

ProteinModelPortalQ5HGK3.
SMRQ5HGK3. Positions 2-305.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING93062.SACOL1244.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW38078; AAW38078; SACOL1244.
GeneID3238625.
KEGGsac:SACOL1244.
PATRIC19528733. VBIStaAur112458_1219.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0331.
HOGENOMHOG000036504.
KOK00645.
OMAPVVTNVE.
OrthoDBEOG6W19KW.
ProtClustDBCLSK885219.

Enzyme and pathway databases

BioCycSAUR93062:GCEP-1227-MONOMER.
UniPathwayUPA00094.

Family and domain databases

Gene3D3.40.366.10. 2 hits.
InterProIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFPIRSF000446. Mct. 1 hit.
SUPFAMSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsTIGR00128. fabD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFABD_STAAC
AccessionPrimary (citable) accession number: Q5HGK3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: February 15, 2005
Last modified: November 13, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways