Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative pyruvate, phosphate dikinase regulatory protein

Gene

SACOL1620

Organism
Staphylococcus aureus (strain COL)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.UniRule annotation

Catalytic activityi

ADP + [pyruvate, phosphate dikinase] = AMP + [pyruvate, phosphate dikinase] phosphate.UniRule annotation
[Pyruvate, phosphate dikinase] phosphate + phosphate = [pyruvate, phosphate dikinase] + diphosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi151 – 1588ADPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

Nucleotide-binding

Enzyme and pathway databases

BioCyciSAUR93062:GCEP-1586-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pyruvate, phosphate dikinase regulatory proteinUniRule annotation (EC:2.7.11.32UniRule annotation, EC:2.7.4.27UniRule annotation)
Short name:
PPDK regulatory proteinUniRule annotation
Gene namesi
Ordered Locus Names:SACOL1620
OrganismiStaphylococcus aureus (strain COL)
Taxonomic identifieri93062 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000530 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 272272Putative pyruvate, phosphate dikinase regulatory proteinPRO_0000196715Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi93062.SACOL1620.

Structurei

3D structure databases

ProteinModelPortaliQ5HFJ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CF9. Bacteria.
COG1806. LUCA.
HOGENOMiHOG000218052.
KOiK09773.
OMAiYAQCEFE.
OrthoDBiEOG6KHG2N.

Family and domain databases

HAMAPiMF_00921. PDRP.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026565. PPDK_reg.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5HFJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKIKIIVAS DSIGETAELV ARAGISQFNP KQCKNELLRY PYIESFEDVD
60 70 80 90 100
EVIQVAKDTN AIIVYTLIKP EMKQYMSEKV AEFQLKSVDI MGPLMDLLSA
110 120 130 140 150
SVEEKPYNEP GIVHRLDDAY FKKIDAIEFA VKYDDGKDPK GLPKADIVLL
160 170 180 190 200
GISRTSKTPL SQYLAHKSYK VMNVPIVPEV TPPDGLYDIN PKKCIALKIS
210 220 230 240 250
EEKLNRIRKE RLKQLGLGDT ARYATEARIQ EELNYFEEIV SEIGCPVIDV
260 270
SQKAIEETAN DIIHYIEQNK SK
Length:272
Mass (Da):30,784
Last modified:February 15, 2005 - v1
Checksum:i8120C7BFF18BDB65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA. Translation: AAW38236.1.
RefSeqiWP_000411299.1. NC_002951.2.

Genome annotation databases

EnsemblBacteriaiAAW38236; AAW38236; SACOL1620.
KEGGisac:SACOL1620.
PATRICi19529441. VBIStaAur112458_1575.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA. Translation: AAW38236.1.
RefSeqiWP_000411299.1. NC_002951.2.

3D structure databases

ProteinModelPortaliQ5HFJ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93062.SACOL1620.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW38236; AAW38236; SACOL1620.
KEGGisac:SACOL1620.
PATRICi19529441. VBIStaAur112458_1575.

Phylogenomic databases

eggNOGiENOG4105CF9. Bacteria.
COG1806. LUCA.
HOGENOMiHOG000218052.
KOiK09773.
OMAiYAQCEFE.
OrthoDBiEOG6KHG2N.

Enzyme and pathway databases

BioCyciSAUR93062:GCEP-1586-MONOMER.

Family and domain databases

HAMAPiMF_00921. PDRP.
InterProiIPR005177. Kinase-pyrophosphorylase.
IPR026565. PPDK_reg.
[Graphical view]
PfamiPF03618. Kinase-PPPase. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain."
    Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H.
    , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M.
    J. Bacteriol. 187:2426-2438(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: COL.

Entry informationi

Entry nameiPDRP_STAAC
AccessioniPrimary (citable) accession number: Q5HFJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: February 15, 2005
Last modified: March 16, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.