Q5HE02 (Q5HE02_STAAC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hyaluronate lyase EMBL AAW37070.1
EC=4.2.2.1 EMBL AAW37070.1

Gene names

Name:	hysA EMBL AAW37070.1
Ordered Locus Names:	SACOL2194

Organism

Staphylococcus aureus (strain COL) [Complete proteome] [HAMAP] EMBL AAW37070.1

Taxonomic identifier

93062 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	807 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Lyase EMBL AAW37070.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	carbohydrate binding Inferred from electronic annotation. Source: InterPro hyaluronate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5HE02 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: FFE88EDC07418EB4	FASTA	807	91,985
	10 20 30 40 50 60 MTYRIKKWQK LSTITLLMAG VITLNGGEFR SVDKHQIAVA DTNVQTPDYE KLRNTWLDVN 70 80 90 100 110 120 YGYDKYDENN PDMKKKFDAT EKEATNLLKE MKTESGRKYL WSGAETLETN SSHMTRTYRN 130 140 150 160 170 180 IEKIAEAMRN PKTTLNTDEN KKKVKDALEW LHKNAYGKEP DKKVKELSEN FTKTTGKNTN 190 200 210 220 230 240 LNWWDYEIGT PKSLTNTLIL LNDQFSNEEK KKFTAPIKTF APDSDKILSS VGKAELAKGG 250 260 270 280 290 300 NLVDISKVKL LECIIEEDKD MMKKSIDSFN KVFTYVQDSA TGKERNGFYK DGSYIDHQDV 310 320 330 340 350 360 PYTGAYGVVL LEGISQMMPM IKETPFNDKT QNDTTLKSWI DDGFMPLIYK GEMMDLSRGR 370 380 390 400 410 420 AISRENETSH SASATVMKSL LRLSDAMDDS TKAKYKKIVK SSVESDSSYK QNDYLNSYSD 430 440 450 460 470 480 IDKMKSLMTD NSISKNGLTQ QLKIYNDMDR VTYHNKDLDF AFGLSMTSKN VARYESINGE 490 500 510 520 530 540 NLKGWHTGAG MSYLYNSDVK HYHDNFWVTA DMKRLSGTTT LDNEILKDTD DKKSSKTFVG 550 560 570 580 590 600 GTKVDDQHAS IGMDFENQDK TLTAKKSYFI LNDKIVFLGT GIKSTDSSKN PVTTIENRKA 610 620 630 640 650 660 NGYTLYTDDK QTTNSDNQEN NSVFLESTDT KKNIGYHFLN KPKITVKKES HTGKWKEINK 670 680 690 700 710 720 SQKDTQKTDE YYEVTQKHSN SDNKYGYVLY PGLSKDVFKT KKDEVTVVKQ EDDFHVVKDN 730 740 750 760 770 780 ESVWAGVNYS NSTQTFDINN TKVEVKAKGM FILKKKDDNT YECSFYNPES TNSASDIESK 790 800 ISMTGYSITN KNTSTSNESG VHFELTK

References

[1]

"Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain." Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J., Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J., Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H., Vamathevan J.J., Khouri H. , Utterback T.R., Lee C., Dimitrov G., Jiang L., Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E., Fraser C.M. J. Bacteriol. 187:2426-2438(2005) [PubMed: 15774886] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000046 Genomic DNA. Translation: AAW37070.1.
RefSeq	YP_187005.1. NC_002951.2.
3D structure databases
ProteinModelPortal	Q5HE02.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5HE02.
Protein family/group databases
CAZy	PL8. Polysaccharide Lyase Family 8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000010527; EBSTAP00000010262; EBSTAG00000010526.
GeneID	3238658.
GenomeReviews	Gene locus SACOL2194 in contig CP000046_GR.
KEGG	sac:SACOL2194.
PATRIC	19530674. VBIStaAur112458_2139.
TIGR	SACOL2194.
Phylogenomic databases
eggNOG	NOG04835.
GeneTree	EBGT00050000023753.
HOGENOM	HBG693731.
OMA	GSYIDHT.
ProtClustDB	CLSK885824.
Enzyme and pathway databases
BioCyc	SAUR93062:SACOL2194-MONOMER.
Family and domain databases
InterPro	IPR008929. Chondroitin_lyas. IPR011013. Glyco_hydro-type_carb-bd. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR011071. Lyase_8-like_C. IPR012970. Lyase_8_alpha_N. IPR004103. Lyase_8_C. IPR003159. Lyase_8_central_dom. IPR012329. Lyase_8_N. [Graphical view]
Gene3D	G3DSA:2.70.98.10. Glyco_hydro_42_D5. 1 hit. G3DSA:2.60.220.10. Lyase_8_C. 1 hit. G3DSA:1.50.10.100. Lyase_8_N. 1 hit.
KO	K01727.
Pfam	PF02278. Lyase_8. 1 hit. PF02884. Lyase_8_C. 1 hit. PF08124. Lyase_8_N. 1 hit. [Graphical view]
SUPFAM	SSF48230. Chondroitin_lyas. 1 hit. SSF74650. Gal_mut_like. 1 hit. SSF49863. Lyase_like_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5HE02_STAAC

Accession

Primary (citable) accession number: Q5HE02

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)