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Protein

ATP-dependent Clp protease ATP-binding subunit ClpL

Gene

clpL

Organism
Staphylococcus aureus (strain COL)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for the development of induced thermotolerance.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi126 – 133ATPSequence analysis8
Nucleotide bindingi457 – 464ATPSequence analysis8

GO - Molecular functioni

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent Clp protease ATP-binding subunit ClpL
Gene namesi
Name:clpL
Ordered Locus Names:SACOL2563
OrganismiStaphylococcus aureus (strain COL)
Taxonomic identifieri93062 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000530 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002694971 – 701ATP-dependent Clp protease ATP-binding subunit ClpLAdd BLAST701

Interactioni

Protein-protein interaction databases

STRINGi93062.SACOL2563.

Structurei

3D structure databases

ProteinModelPortaliQ5HD02.
SMRiQ5HD02.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini336 – 371UVRAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni81 – 332IAdd BLAST252
Regioni383 – 575IIAdd BLAST193

Sequence similaritiesi

Belongs to the ClpA/ClpB family. ClpL subfamily.Curated

Phylogenomic databases

eggNOGiCOG0542. LUCA.
HOGENOMiHOG000218211.
KOiK04086.
OMAiKRMFTPE.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR001270. ClpA/B.
IPR027417. P-loop_NTPase.
IPR001943. UVR_dom.
PfamiView protein in Pfam
PF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF02151. UVR. 1 hit.
PRINTSiPR00300. CLPPROTEASEA.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5HD02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNGFFNSDF DSIFRRMMKD MQGSNQVGNK KYYINGKEVS PEELAQLTQQ
60 70 80 90 100
GGNHSAEQSA QAFQQAAQRQ QGQQGGNGNY LEQIGRNLTQ EARDGLLDPV
110 120 130 140 150
IGRDKEIQET AEVLSRRTKN NPILVGEAGV GKTAIVEGLA QAIVEGNVPA
160 170 180 190 200
AIKDKEIISV DISSLEAGTQ YRGAFEENIQ KLIEGVKSSQ NAVLFFDEIH
210 220 230 240 250
QIIGSGATGS DSGSKGLSDI LKPALSRGEI SIIGATTQDE YRNNILKDAA
260 270 280 290 300
LTRRFNEVLV NEPSAKDTVE ILKGIREKFE EHHQVKLPDD VLKACVDLSI
310 320 330 340 350
QYIPQRLLPD KAIDVLDITA AHLSAQSPAV DKVETEKRIS ELENDKRKAV
360 370 380 390 400
SAEEYKKADD IQNEIKSLQD KLENSNGEHT AVATVHDISD TIQRLTGIPV
410 420 430 440 450
SQMDDNDIER LKNISNRLRS KIIGQDQAVE MVSRAIRRNR AGFDDGNRPI
460 470 480 490 500
GSFLFVGPTG VGKTELAKQL AIDLFGNKDA LIRLDMSEYS DTTAVSKMIG
510 520 530 540 550
TTAGYVGYDD NSNTLTEKVR RNPYSVILFD EIEKANPQIL TLLLQVMDDG
560 570 580 590 600
NLTDGQGNVI NFKNTIIICT SNAGFGNGND AEEKDIMHEM KKFFRPEFLN
610 620 630 640 650
RFNGIVEFLH LDKDALQDIV NLLLDDVQVT LDKKGITMDV SQDAKDWLIE
660 670 680 690 700
EGYDEELGAR PLRRIVEQQV RDKITDYYLD HTDVKHVDID VEDNELVVKG

K
Length:701
Mass (Da):77,836
Last modified:February 15, 2005 - v1
Checksum:iFBC87C248EE580B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000046 Genomic DNA. Translation: AAW37339.1.
RefSeqiWP_001058981.1. NC_002951.2.

Genome annotation databases

EnsemblBacteriaiAAW37339; AAW37339; SACOL2563.
KEGGisac:SACOL2563.

Similar proteinsi

Entry informationi

Entry nameiCLPL_STAAC
AccessioniPrimary (citable) accession number: Q5HD02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: February 15, 2005
Last modified: June 7, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families