Q5HBR7 (Q5HBR7_EHRRW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Probable ubiquinone biosynthesis protein EMBL CAI26757.1

Submitted name:
Putative ubiquinone biosynthesis protein UbiB EMBL CAH57977.1

Gene names

Name:	probable ubiB EMBL CAH57977.1
Synonyms:	ubiB EMBL CAI26757.1
Ordered Locus Names:	Erum2600, ERWE_CDS_02630

Organism

Ehrlichia ruminantium (strain Welgevonden) [Complete proteome] [HAMAP]

Taxonomic identifier

254945 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia › canis group › Ehrlichia ruminantium

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis By similarity. SAAS SAAS004147
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity. Cell inner membrane; Single-pass membrane protein By similarity.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis SAAS SAAS004147
Cellular component	Cell inner membrane SAAS SAAS004147 Cell membrane Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004147
Ligand	Ubiquinone EMBL CAH57977.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ubiquinone biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5HBR7 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 964D4C012D5D3E6A	FASTA	480	55,489
	10 20 30 40 50 60 MLNVFSHIFS ILGIFSVLVR YNVLPYTYLL AKRSVRKRPK GEKITMALQK LGPIFIKFGQ 70 80 90 100 110 120 SISSRGDIIG EEIANHLLFL CDKLPAFSYS DVVRTIEEDF KCAISEIFCE FDEVPIAAAS 130 140 150 160 170 180 ISQVHKAKDI DGNIRAVKIL RPKIDQIFEK NIKLMFWIAK IAQHFQSLRR FQLLELVQTF 190 200 210 220 230 240 HEICKMEIDL RFEAANADEL RGNMQDDSAC YIPQVDWNRT TRRVLTLEWV DAIPIYNFYN 250 260 270 280 290 300 LENNEALVKN LIFCFCNQVY RDRLFHADMH PGNLMVDTNG KIVIIDFGIV GRLDKATCMY 310 320 330 340 350 360 VTEILVGFIK RDYQYVADVH YRAGYVDAKY SSFITACRAI GEPIVGKNTD NISIAALLSQ 370 380 390 400 410 420 LFKVTADFDM KLQPQLFLLQ KTTVLVEGVC RQLSPSINMW KVAELWMEKY AVDKNKYLKK 430 440 450 460 470 480 LRKSCLYQTM YDVTSFMKKV DRSLDIINNY DEINHSKYSI SRDLMWAIIV IVLVIKIIIG

References

[1]

"The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number." Collins N.E., Liebenberg J., de Villiers E.P., Brayton K.A., Louw E., Pretorius A., Faber F.E., van Heerden H., Josemans A., van Kleef M., Steyn H.C., van Strijp M.F., Zweygarth E., Jongejan F., Maillard J.C., Berthier D., Botha M., Joubert F. , Corton C.H., Thomson N.R., Allsopp M.T., Allsopp B.A. Proc. Natl. Acad. Sci. U.S.A. 102:838-843(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [ARC-OVI].

[2]

"Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity." Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D. J. Bacteriol. 188:2533-2542(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [CIRAD].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR767821 Genomic DNA. Translation: CAH57977.1. CR925678 Genomic DNA. Translation: CAI26757.1.
RefSeq	YP_180127.1. NC_005295.2. YP_197139.1. NC_006832.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	254945.Erum2600.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAH57977; CAH57977; Erum2600. CAI26757; CAI26757; ERWE_CDS_02630.
GeneID	3232619. 3260694.
KEGG	eru:Erum2600. erw:ERWE_CDS_02630.
PATRIC	20580316. VBIEhrRum92411_0281.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0661.
HOGENOM	HOG000264438.
KO	K03688.
OMA	FITACRA.
ProtClustDB	CLSK749567.
Enzyme and pathway databases
BioCyc	ERUM254945:GJ2L-279-MONOMER.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR018934. RIO-like_kinase. IPR010232. UbiB. IPR004147. UbiB_dom. [Graphical view]
Pfam	PF03109. ABC1. 1 hit. PF01163. RIO1. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR01982. UbiB. 1 hit.
PROSITE	PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5HBR7_EHRRW

Accession

Primary (citable) accession number: Q5HBR7
Secondary accession number(s): Q5FE67

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)