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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Ehrlichia ruminantium (strain Welgevonden)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi8Divalent metal cationUniRule annotation1
Metal bindingi9Divalent metal cationUniRule annotation1
Metal bindingi42Divalent metal cationUniRule annotation1
Metal bindingi94Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandMetal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:Erum3050, ERWE_CDS_03100
OrganismiEhrlichia ruminantium (strain Welgevonden)
Taxonomic identifieri254945 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
Proteomesi
  • UP000001021 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002356151 – 2525'-nucleotidase SurEAdd BLAST252

Interactioni

Protein-protein interaction databases

STRINGi254945.ERWE_CDS_03100.

Structurei

3D structure databases

ProteinModelPortaliQ5HBM5.
SMRiQ5HBM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OrthoDBiPOG091H01CP.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE. 1 hit.
InterProiView protein in InterPro
IPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
IPR036523. SurE-like_sf.
PfamiView protein in Pfam
PF01975. SurE. 1 hit.
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5HBM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLLSNDDG FHANGIKALK EIVIKSGIAS EIWVVAPLNN CSGSGRSVGL
60 70 80 90 100
NVKVQVSKVS DTEFIVDSTP STSVFLALRK IMNYKPDLIL SGINHGVNIG
110 120 130 140 150
NDVWYSGTVA AAAEGAAINI PSIAISQEYD NKSGEINWVN PQRFLKQIIE
160 170 180 190 200
MLMNVSFWNK STVMNVNFPL MPAKGIKFTD QGKYVPCNEI EKNESSDDSN
210 220 230 240 250
VSYTITRITP NKKNRAQCDG SIKAIDEGYI TITPLKFDMT DFDVLTSLNS

LK
Length:252
Mass (Da):27,644
Last modified:February 15, 2005 - v1
Checksum:i9ACBA0F99EE3B957
GO

Sequence cautioni

The sequence CAI26804 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR767821 Genomic DNA. Translation: CAH58022.1.
CR925678 Genomic DNA. Translation: CAI26804.1. Different initiation.

Genome annotation databases

EnsemblBacteriaiCAH58022; CAH58022; Erum3050.
CAI26804; CAI26804; ERWE_CDS_03100.
KEGGieru:Erum3050.
erw:ERWE_CDS_03100.

Similar proteinsi

Entry informationi

Entry nameiSURE_EHRRW
AccessioniPrimary (citable) accession number: Q5HBM5
Secondary accession number(s): Q5FEB8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: February 15, 2005
Last modified: November 22, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families