Q5HBI1 (Q5HBI1_EHRRW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aspartate aminotransferase (Transaminase A) EMBL CAI26850.1

Submitted name:
Aspartate aminotransferase A EMBL CAH58069.1
EC=2.6.1.1 EMBL CAH58069.1

Gene names

Name:	aatA EMBL CAH58069.1
Ordered Locus Names:	Erum3490, ERWE_CDS_03560

Organism

Ehrlichia ruminantium (strain Welgevonden) [Complete proteome] [HAMAP]

Taxonomic identifier

254945 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000479
Sequence similarities	Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU000479

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000479
Molecular function	Aminotransferase RuleBase RU000481 EMBL CAH58069.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro L-aspartate:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5HBI1 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: DA9938714145A066	FASTA	399	44,268
	10 20 30 40 50 60 MSFLSKRMEC IKPSPTLEIA SQAQKLKMLG RDIISLSAGE PDFDTPEHIK QAAINALNLG 70 80 90 100 110 120 KTKYTAVDGI IELKKAIISR LKQDHNLIYD VSQISVGNGA KQCIYNLFMS TLNDGDEVII 130 140 150 160 170 180 PAPYWVSYPD IVKIAGGNPV IIDCSSTSKL SAELLENAIT DKTKWLILNS PNNPSGLVYT 190 200 210 220 230 240 YDELKDIAQV LLKYSNVHIM TDDIYSKIVY DDLKFFTIAQ VEEDLYSRVF LVNGVSKAYA 250 260 270 280 290 300 MTGWRIGYIA GASEVIKAIS VIQSQSTTNP NSIAQFAAVE ALTGDQKFLE ERNKVFIERR 310 320 330 340 350 360 DIMLDMINNT PLLSAEKPQG AFYVFISCKE LIGRTTKSGF CITSAMDFTK YLLEDYNIAV 370 380 390 VPGEAFGVQG FFRVSYATST QCVSEACDRI LTACNELIY

References

[1]

"The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number." Collins N.E., Liebenberg J., de Villiers E.P., Brayton K.A., Louw E., Pretorius A., Faber F.E., van Heerden H., Josemans A., van Kleef M., Steyn H.C., van Strijp M.F., Zweygarth E., Jongejan F., Maillard J.C., Berthier D., Botha M., Joubert F. , Corton C.H., Thomson N.R., Allsopp M.T., Allsopp B.A. Proc. Natl. Acad. Sci. U.S.A. 102:838-843(2005) [PubMed: 15637156] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [ARC-OVI].

[2]

"Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity." Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D. J. Bacteriol. 188:2533-2542(2006) [PubMed: 16547041] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [CIRAD].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR767821 Genomic DNA. Translation: CAH58069.1. CR925678 Genomic DNA. Translation: CAI26850.1.
RefSeq	YP_180213.1. NC_005295.2. YP_197232.1. NC_006832.1.
3D structure databases
ProteinModelPortal	Q5HBI1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5HBI1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3233266. 3261117.
GenomeReviews	Gene locus Erum3490 in contig CR767821_GR. Gene locus ERWE_CDS_03560 in contig CR925678_GR.
KEGG	eru:Erum3490. erw:ERWE_CDS_03560.
PATRIC	20580520. VBIEhrRum92411_0380.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0436.
HOGENOM	HBG645860.
OMA	MASLDKG.
PhylomeDB	Q5HBI1.
ProtClustDB	CLSK749316.
Family and domain databases
InterPro	IPR001176. ACC_synthase. IPR004839. Aminotransferase_I/II. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00812.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
PRINTS	PR00753. ACCSYNTHASE.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5HBI1_EHRRW

Accession

Primary (citable) accession number: Q5HBI1
Secondary accession number(s): Q5FEG7

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)