Q5HBF5 (Q5HBF5_EHRRW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyguanosinetriphosphate triphosphohydrolase-like protein HAMAP MF_01212

Gene names

Ordered Locus Names:

Erum3740, ERWE_CDS_03860

Organism

Ehrlichia ruminantium (strain Welgevonden) [Complete proteome] [HAMAP]

Taxonomic identifier

254945 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length	403 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dGTPase family. Type 2 subfamily. HAMAP MF_01212

Ontologies

Keywords
Molecular function	Hydrolase SAAS SAAS023293 HAMAP MF_01212 EMBL CAH58096.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	GTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dGTPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5HBF5 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 9D0FC9F3753A26DA	FASTA	403	47,354
	10 20 30 40 50 60 MSNYKLMLDL VKYACDPLET RGRVFPESED PYRSCYQRDR DRIIYSGAFR KLQYKTQVFI 70 80 90 100 110 120 NYENDYYRTR LTHSLEVAQI ARSLSRRLCV NEDLTEAISL AHDLGHPPFG HAGEEALNEM 130 140 150 160 170 180 TQHYLGFDHN VQALRILTFL EKRYLKFDGI NLTWESLEGI AKHNGPITGK HCVNPIKRVH 190 200 210 220 230 240 KFILDYDRDY KLDLDNFSSA EAQIAAISDD IAYNMHDIDD GIRAKILVVD ELLELPLIGR 250 260 270 280 290 300 ILKKIIDENT NYDISDNKVI HEFLRKTVDT MIEDVVYQVK SNVREYNIYS QSDIRNLGKV 310 320 330 340 350 360 FVTFSAEMMQ YHASIKNFLR SKLYNYYKVK RVKNKVKRII KELFKAFYED PQILPPDWSI 370 380 390 400 KAMNTDLLGK SIVVCDFISG MTDRFAIQEH RRIFDTKYEM QLF

References

[1]

"The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number." Collins N.E., Liebenberg J., de Villiers E.P., Brayton K.A., Louw E., Pretorius A., Faber F.E., van Heerden H., Josemans A., van Kleef M., Steyn H.C., van Strijp M.F., Zweygarth E., Jongejan F., Maillard J.C., Berthier D., Botha M., Joubert F. , Corton C.H., Thomson N.R., Allsopp M.T., Allsopp B.A. Proc. Natl. Acad. Sci. U.S.A. 102:838-843(2005) [PubMed: 15637156] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [ARC-OVI].

[2]

"Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity." Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D. J. Bacteriol. 188:2533-2542(2006) [PubMed: 16547041] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [CIRAD].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR767821 Genomic DNA. Translation: CAH58096.1. CR925678 Genomic DNA. Translation: CAI26880.1.
RefSeq	YP_180239.1. NC_005295.2. YP_197262.1. NC_006832.1.
3D structure databases
ProteinModelPortal	Q5HBF5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5HBF5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3233003. 3261323.
GenomeReviews	Gene locus Erum3740 in contig CR767821_GR. Gene locus ERWE_CDS_03860 in contig CR925678_GR.
KEGG	eru:Erum3740. erw:ERWE_CDS_03860.
PATRIC	20580583. VBIEhrRum92411_0410.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0232.
HOGENOM	HBG500914.
OMA	QVFINYE.
PhylomeDB	Q5HBF5.
ProtClustDB	CLSK749306.
Family and domain databases
HAMAP	MF_01212. dGTPase_type2. [Tree]
InterPro	IPR006261. dGTP_triP_hydro. IPR023293. dGTP_triP_hydro_central. IPR023023. dGTP_triP_hydro_type2. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. [Graphical view]
Gene3D	G3DSA:1.10.3410.10. G3DSA:1.10.3410.10. 1 hit. G3DSA:1.10.3210.10. HD. 1 hit.
KO	K01129.
Pfam	PF01966. HD. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01353. DGTP_triPase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5HBF5_EHRRW

Accession

Primary (citable) accession number: Q5HBF5
Secondary accession number(s): Q5FDU9

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)