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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Ehrlichia ruminantium (strain Welgevonden)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciERUM254945:ERUM_RS02685-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Erum4910, ERWE_CDS_05130
OrganismiEhrlichia ruminantium (strain Welgevonden)
Taxonomic identifieri254945 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeEhrlichia
Proteomesi
  • UP000001021 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420201 – 576Arginine--tRNA ligaseAdd BLAST576

Proteomic databases

PRIDEiQ5HB39

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi254945.ERWE_CDS_05130

Structurei

3D structure databases

ProteinModelPortaliQ5HB39
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q5HB39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVACTIRRH IIEKLHVLNI DNFVVTNESI LAKLIVDYPN NPDHGDLYTN
60 70 80 90 100
AALILSKYIK KNPMDIAKIL VDEFSSIKEI SDINVVKPGF INFNISLDVW
110 120 130 140 150
YEIIISINRL KEKFGHVNFG NGKRVNIEFV SANPTGPMHI GHARGAIFGD
160 170 180 190 200
VLANLLERVG YEVVREYYIN DAGAQIDVLV ESVYLRYKEV LGENIVIGSG
210 220 230 240 250
LYPGLYLKDI GKLLYQEYDS GLLGMDYSQR RRIIRDVSLM YLMKLIKEDL
260 270 280 290 300
ALLGIKHDIF TSESQLQKDN IVQKCVELLQ EKQLIYYGTL DQPKGTEGIN
310 320 330 340 350
WKPRTQMLFK STDFGDDVDR ALQKADGSWT YFANDIAYHF YKISRGFQHM
360 370 380 390 400
ILELGSDHIG YVKRLKAAVK ALSDGNATID IKLHSIVNFL DNGAQVKMSK
410 420 430 440 450
RSGEFLTIKD VIEKVGKDVV RFIMLTRKSD VVLDFDFAKV VEQSKNNPVF
460 470 480 490 500
YVQYAHARVH SLIRNAPKIL EIELVDFSVL SSKEEILLIK LLAKWQDIVE
510 520 530 540 550
ISAKTAEPHR ITFYLIEIAE AFHALWGYGN KSTDMRFIVD NNINLTSARI
560 570
YLAKSVGYVI ASGLTIFSIV PLTEMK
Length:576
Mass (Da):65,451
Last modified:February 15, 2005 - v1
Checksum:i50E4873206E02080
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR767821 Genomic DNA Translation: CAH58219.1
CR925678 Genomic DNA Translation: CAI27007.1
RefSeqiWP_011155172.1, NC_006832.1

Genome annotation databases

EnsemblBacteriaiCAH58219; CAH58219; Erum4910
CAI27007; CAI27007; ERWE_CDS_05130
GeneIDi33058025
KEGGieru:Erum4910
erw:ERWE_CDS_05130

Similar proteinsi

Entry informationi

Entry nameiSYR_EHRRW
AccessioniPrimary (citable) accession number: Q5HB39
Secondary accession number(s): Q5FEH9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 15, 2005
Last modified: June 20, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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