Q5HAS9 (RL16_EHRRW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L16

Gene names

Name:	rplP
Ordered Locus Names:	Erum6000, ERWE_CDS_06310

Organism

Ehrlichia ruminantium (strain Welgevonden) [Complete proteome] [HAMAP]

Taxonomic identifier

254945 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia › canis group › Ehrlichia ruminantium

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs By similarity. HAMAP-Rule MF_01342
Subunit structure	Part of the 50S ribosomal subunit By similarity. HAMAP-Rule MF_01342
Sequence similarities	Belongs to the ribosomal protein L16P family.

Ontologies

Keywords
Domain	Repeat
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 136	136	50S ribosomal protein L16 HAMAP-Rule MF_01342		PRO_0000062098

Sequences

	Sequence		Length	Mass (Da)
	Q5HAS9 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 1EAE7A3764EBD66A	FASTA	136	15,208
	10 20 30 40 50 60 MFIPKKTKYK KDFKGRISGN AKGGYTLAFG TYGLKSLEPG RLTSKQVESA RRSISRTLKR 70 80 90 100 110 120 VGKVWIRVFC HTPVSKKPMD VRMGKGKGSI EMWVCKVKPG KILFEISGVS LNLAKEALQK 130 SQAKLPVKCK FISDEL

References

[1]

"The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number." Collins N.E., Liebenberg J., de Villiers E.P., Brayton K.A., Louw E., Pretorius A., Faber F.E., van Heerden H., Josemans A., van Kleef M., Steyn H.C., van Strijp M.F., Zweygarth E., Jongejan F., Maillard J.C., Berthier D., Botha M., Joubert F. , Corton C.H., Thomson N.R., Allsopp M.T., Allsopp B.A. Proc. Natl. Acad. Sci. U.S.A. 102:838-843(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden.

[2]

"Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity." Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D. J. Bacteriol. 188:2533-2542(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR767821 Genomic DNA. Translation: CAH58332.1. CR925678 Genomic DNA. Translation: CAI27125.1.
RefSeq	YP_180465.1. NC_005295.2. YP_197507.1. NC_006832.1.
3D structure databases
ProteinModelPortal	Q5HAS9.
ModBase	Search...
Protein-protein interaction databases
STRING	254945.Erum6000.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAH58332; CAH58332; Erum6000. CAI27125; CAI27125; ERWE_CDS_06310.
GeneID	3232675. 3260744.
KEGG	eru:Erum6000. erw:ERWE_CDS_06310.
PATRIC	20581112. VBIEhrRum92411_0665.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0197.
HOGENOM	HOG000164573.
KO	K02878.
OMA	GAPEYWV.
ProtClustDB	PRK09203.
Enzyme and pathway databases
BioCyc	ERUM254945:GJ2L-661-MONOMER.
Family and domain databases
Gene3D	3.90.1170.10. 1 hit.
HAMAP	MF_01342. Ribosomal_L16.
InterPro	IPR016180. Ribosomal_L10e/L16. IPR000114. Ribosomal_L16. IPR020798. Ribosomal_L16_CS. [Graphical view]
PANTHER	PTHR12220. PTHR12220. 1 hit.
Pfam	PF00252. Ribosomal_L16. 1 hit. [Graphical view]
PRINTS	PR00060. RIBOSOMALL16.
SUPFAM	SSF54686. Ribosomal_L10e/L16. 1 hit.
TIGRFAMs	TIGR01164. rplP_bact. 1 hit.
PROSITE	PS00586. RIBOSOMAL_L16_1. False negative. PS00701. RIBOSOMAL_L16_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL16_EHRRW

Accession

Primary (citable) accession number: Q5HAS9
Secondary accession number(s): Q5FD65

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
Last sequence update:	February 15, 2005
Last modified:	May 29, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program