Q5HAI2 (Q5HAI2_EHRRW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase HAMAP MF_00146
Short name=dCTP deaminase HAMAP MF_00146
EC=3.5.4.13 HAMAP MF_00146

Gene names

Name:	probable dcd EMBL CAH58431.1
Synonyms:	dcd HAMAP MF_00146 EMBL CAI27228.1
Ordered Locus Names:	Erum6990, ERWE_CDS_07340

Organism

Ehrlichia ruminantium (strain Welgevonden) [Complete proteome] [HAMAP]

Taxonomic identifier

254945 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Ehrlichia

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. SAAS SAAS011962 HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. SAAS SAAS011962 HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family. HAMAP MF_00146

Ontologies

Keywords
Biological process	Nucleotide metabolism SAAS SAAS011962 HAMAP MF_00146
Molecular function	Hydrolase SAAS SAAS011962 HAMAP MF_00146 EMBL CAH58431.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5HAI2 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: BFAD7DEFB25A8D86	FASTA	185	20,669
	10 20 30 40 50 60 MSVMPDHWIK DKAIKDKMIN PFTDHKKSSG VLSYGLSSYG YDARIDNKFK IFTNVNSVTV 70 80 90 100 110 120 DPKNFPLGSF VNKEEDVCII PPNSFVLAKT VEYFRIPKDV LVICVGKSTY ARCGIIVNVT 130 140 150 160 170 180 PLEPGWEGYV TLEFSNTTPL PAKIYAFEGA CQFIFLKGDS ECSASYNELK GKYMNQLGVT LPIVK

References

[1]

"The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number." Collins N.E., Liebenberg J., de Villiers E.P., Brayton K.A., Louw E., Pretorius A., Faber F.E., van Heerden H., Josemans A., van Kleef M., Steyn H.C., van Strijp M.F., Zweygarth E., Jongejan F., Maillard J.C., Berthier D., Botha M., Joubert F. , Corton C.H., Thomson N.R., Allsopp M.T., Allsopp B.A. Proc. Natl. Acad. Sci. U.S.A. 102:838-843(2005) [PubMed: 15637156] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [ARC-OVI].

[2]

"Comparative genomic analysis of three strains of Ehrlichia ruminantium reveals an active process of genome size plasticity." Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y., Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D. J. Bacteriol. 188:2533-2542(2006) [PubMed: 16547041] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Welgevonden [CIRAD].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR767821 Genomic DNA. Translation: CAH58431.1. CR925678 Genomic DNA. Translation: CAI27228.1.
RefSeq	YP_180562.1. NC_005295.2. YP_197610.1. NC_006832.1.
3D structure databases
ProteinModelPortal	Q5HAI2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5HAI2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3233486. 3261037.
GenomeReviews	Gene locus Erum6990 in contig CR767821_GR. Gene locus ERWE_CDS_07340 in contig CR925678_GR.
KEGG	eru:Erum6990. erw:ERWE_CDS_07340.
PATRIC	20581344. VBIEhrRum92411_0778.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	IFRHIPG.
PhylomeDB	Q5HAI2.
ProtClustDB	PRK00416.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. [Graphical view]
KO	K01494.
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5HAI2_EHRRW

Accession

Primary (citable) accession number: Q5HAI2
Secondary accession number(s): Q5FDH7

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	December 14, 2011
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)