SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5H9L2

- TCAL5_HUMAN

UniProt

Q5H9L2 - TCAL5_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Transcription elongation factor A protein-like 5
Gene
TCEAL5
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

May be involved in transcriptional regulation.

GO - Molecular functioni

  1. protein binding Source: IntAct

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription elongation factor A protein-like 5
Short name:
TCEA-like protein 5
Alternative name(s):
Transcription elongation factor S-II protein-like 5
Gene namesi
Name:TCEAL5
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:22282. TCEAL5.

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134950668.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 206206Transcription elongation factor A protein-like 5
PRO_0000239211Add
BLAST

Proteomic databases

PaxDbiQ5H9L2.
PRIDEiQ5H9L2.

PTM databases

PhosphoSiteiQ5H9L2.

Expressioni

Gene expression databases

BgeeiQ5H9L2.
CleanExiHS_TCEAL5.
GenevestigatoriQ5H9L2.

Organism-specific databases

HPAiHPA045564.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
NR4A2P433542EBI-2681773,EBI-2681738

Protein-protein interaction databases

BioGridi131070. 1 interaction.
IntActiQ5H9L2. 4 interactions.
STRINGi9606.ENSP00000361765.

Structurei

3D structure databases

ProteinModelPortaliQ5H9L2.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi2 – 8180Glu-rich
Add
BLAST

Sequence similaritiesi

Belongs to the TFS-II family. TFA subfamily.

Phylogenomic databases

eggNOGiNOG85288.
HOGENOMiHOG000231342.
HOVERGENiHBG055896.
InParanoidiQ5H9L2.
OMAiPENKGRA.
OrthoDBiEOG7QNVNM.
PhylomeDBiQ5H9L2.
TreeFamiTF336871.

Family and domain databases

InterProiIPR021156. TF_A-like/BEX-like.
IPR010370. TFA.
[Graphical view]
PANTHERiPTHR14754. PTHR14754. 1 hit.
PfamiPF04538. BEX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5H9L2-1 [UniParc]FASTAAdd to Basket

« Hide

MEKLYKENEG KPENERNLES EGKPEDEGST EDEGKSDEEE KPDMEGKTEC    50
EGKREDEGEP GDEGQLEDEG NQEKQGKSEG EDKPQSEGKP ASQAKPESQP 100
RAAEKRPAED YVPRKAKRKT DRGTDDSPKD SQEDLQERHL SSEEMMRECG 150
DVSRAQEELR KKQKMGGFHW MQRDVQDPFA PRGQRGVRGV RGGGRGQKDL 200
EDVPYV 206
Length:206
Mass (Da):23,307
Last modified:February 15, 2005 - v1
Checksum:iCCDB6A1ACCCE3BAD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z68694 Genomic DNA. Translation: CAI41976.1.
CH471190 Genomic DNA. Translation: EAW54717.1.
BC132922 mRNA. Translation: AAI32923.1.
BC132924 mRNA. Translation: AAI32925.1.
CCDSiCCDS35356.1.
RefSeqiNP_001012997.1. NM_001012979.2.
UniGeneiHs.403462.

Genome annotation databases

EnsembliENST00000372680; ENSP00000361765; ENSG00000204065.
GeneIDi340543.
KEGGihsa:340543.
UCSCiuc004ejz.2. human.

Polymorphism databases

DMDMi74762182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z68694 Genomic DNA. Translation: CAI41976.1 .
CH471190 Genomic DNA. Translation: EAW54717.1 .
BC132922 mRNA. Translation: AAI32923.1 .
BC132924 mRNA. Translation: AAI32925.1 .
CCDSi CCDS35356.1.
RefSeqi NP_001012997.1. NM_001012979.2.
UniGenei Hs.403462.

3D structure databases

ProteinModelPortali Q5H9L2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 131070. 1 interaction.
IntActi Q5H9L2. 4 interactions.
STRINGi 9606.ENSP00000361765.

PTM databases

PhosphoSitei Q5H9L2.

Polymorphism databases

DMDMi 74762182.

Proteomic databases

PaxDbi Q5H9L2.
PRIDEi Q5H9L2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000372680 ; ENSP00000361765 ; ENSG00000204065 .
GeneIDi 340543.
KEGGi hsa:340543.
UCSCi uc004ejz.2. human.

Organism-specific databases

CTDi 340543.
GeneCardsi GC0XM102528.
HGNCi HGNC:22282. TCEAL5.
HPAi HPA045564.
neXtProti NX_Q5H9L2.
PharmGKBi PA134950668.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG85288.
HOGENOMi HOG000231342.
HOVERGENi HBG055896.
InParanoidi Q5H9L2.
OMAi PENKGRA.
OrthoDBi EOG7QNVNM.
PhylomeDBi Q5H9L2.
TreeFami TF336871.

Miscellaneous databases

GenomeRNAii 340543.
NextBioi 97916.
PROi Q5H9L2.

Gene expression databases

Bgeei Q5H9L2.
CleanExi HS_TCEAL5.
Genevestigatori Q5H9L2.

Family and domain databases

InterProi IPR021156. TF_A-like/BEX-like.
IPR010370. TFA.
[Graphical view ]
PANTHERi PTHR14754. PTHR14754. 1 hit.
Pfami PF04538. BEX. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiTCAL5_HUMAN
AccessioniPrimary (citable) accession number: Q5H9L2
Secondary accession number(s): A2RUJ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: February 15, 2005
Last modified: July 9, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi