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Q5H9F3 (BCORL_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (6) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
BCL-6 corepressor-like protein 1

Short name=BCoR-L1
Short name=BCoR-like protein 1
Gene names
Name:BCORL1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1711 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Ref.5

Subunit structure

Interacts with CTBP1. Interacts with HDAC4, HDAC5 and HDAC7. Interacts with PCGF1; the interaction is direct. Ref.5 Ref.7

Subcellular location

Nucleus Ref.5.

Tissue specificity

Detected in testis and prostate. Detected at lower levels in peripheral blood leukocytes and spleen. Ref.5

Sequence similarities

Belongs to the BCOR family.

Contains 3 ANK repeats.

Sequence caution

The sequence BAC85922.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q5H9F3-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q5H9F3-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1230-1359: Missing.
Isoform 3 (identifier: Q5H9F3-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1434-1434: A → AKGKGRWSQQ...LLQRAARLGY
Note: Contains a phosphoserine at position 1476.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 17111711BCL-6 corepressor-like protein 1
PRO_0000312268

Regions

Repeat1455 – 148430ANK 1
Repeat1488 – 151730ANK 2
Repeat1521 – 154929ANK 3
Motif1328 – 13369Nuclear localization signal Potential
Compositional bias198 – 649452Pro-rich

Amino acid modifications

Modified residue6131Phosphoserine Ref.6
Modified residue10331Phosphoserine Ref.6
Modified residue11621Phosphoserine Ref.6

Natural variations

Alternative sequence1230 – 1359130Missing in isoform 2.
VSP_029778
Alternative sequence14341A → AKGKGRWSQQKTRSPKSPTP VKPTEPCTPSKSRSASSEEA SESPTARQIPPEARRLIVNK NAGETLLQRAARLGY in isoform 3.
VSP_029779
Natural variant1111F → L. Ref.2
Corresponds to variant rs4830173 [ dbSNP | Ensembl ].
VAR_061020
Natural variant2091G → S.
Corresponds to variant rs5932715 [ dbSNP | Ensembl ].
VAR_037467
Natural variant8201N → S Found in a patient with severe intellectual disability, coarse face and hypotonia; unknown pathological significance. Ref.9
VAR_070559
Natural variant8321G → D in a breast cancer sample; somatic mutation. Ref.8
VAR_037468

Experimental info

Mutagenesis623 – 6242DL → AS: Strongly reduced repressor activity. Interferes with CTBP1 binding. Ref.5
Mutagenesis16651L → D or R: Slightly inhibits interaction with PCGF1. Ref.5 Ref.7
Sequence conflict15641V → A in BAC85922. Ref.4

Secondary structure

....................... 1711
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: DD78A00598703C53

FASTA1,711182,526
        10         20         30         40         50         60 
MISTAPLYSG VHNWTSSDRI RMCGINEERR APLSDEESTT GDCQHFGSQE FCVSSSFSKV 

        70         80         90        100        110        120 
ELTAVGSGSN ARGADPDGSA TEKLGHKSED KPDDPQPKMD YAGNVAEAEG FLVPLSSPGD 

       130        140        150        160        170        180 
GLKLPASDSA EASNSRADCS WTPLNTQMSK QVDCSPAGVK ALDSRQGVGE KNTFILATLG 

       190        200        210        220        230        240 
TGVPVEGTLP LVTTNFSPLP APICPPAPGS ASVPHSVPDA FQVPLSVPAP VPHSGLVPVQ 

       250        260        270        280        290        300 
VATSVPAPSP PLAPVPALAP APPSVPTLIS DSNPLSVSAS VLVPVPASAP PSGPVPLSAP 

       310        320        330        340        350        360 
APAPLSVPVS APPLALIQAP VPPSAPTLVL APVPTPVLAP MPASTPPAAP APPSVPMPTP 

       370        380        390        400        410        420 
TPSSGPPSTP TLIPAFAPTP VPAPTPAPIF TPAPTPMPAA TPAAIPTSAP IPASFSLSRV 

       430        440        450        460        470        480 
CFPAAQAPAM QKVPLSFQPG TVLTPSQPLV YIPPPSCGQP LSVATLPTTL GVSSTLTLPV 

       490        500        510        520        530        540 
LPSYLQDRCL PGVLASPELR SYPYAFSVAR PLTSDSKLVS LEVNRLPCTS PSGSTTTQPA 

       550        560        570        580        590        600 
PDGVPGPLAD TSLVTASAKV LPTPQPLLPA PSGSSAPPHP AKMPSGTEQQ TEGTSVTFSP 

       610        620        630        640        650        660 
LKSPPQLERE MASPPECSEM PLDLSSKSNR QKLPLPNQRK TPPMPVLTPV HTSSKALLST 

       670        680        690        700        710        720 
VLSRSQRTTQ AAGGNVTSCL GSTSSPFVIF PEIVRNGDPS TWVKNSTALI STIPGTYVGV 

       730        740        750        760        770        780 
ANPVPASLLL NKDPNLGLNR DPRHLPKQEP ISIIDQGEPK GTGATCGKKG SQAGAEGQPS 

       790        800        810        820        830        840 
TVKRYTPARI APGLPGCQTK ELSLWKPTGP ANIYPRCSVN GKPTSTQVLP VGWSPYHQAS 

       850        860        870        880        890        900 
LLSIGISSAG QLTPSQGAPI RPTSVVSEFS GVPSLSSSEA VHGLPEGQPR PGGSFVPEQD 

       910        920        930        940        950        960 
PVTKNKTCRI AAKPYEEQVN PVLLTLSPQT GTLALSVQPS GGDIRMNQGP EESESHLCSD 

       970        980        990       1000       1010       1020 
STPKMEGPQG ACGLKLAGDT KPKNQVLATY MSHELVLATP QNLPKMPELP LLPHDSHPKE 

      1030       1040       1050       1060       1070       1080 
LILDVVPSSR RGSSTERPQL GSQVDLGRVK MEKVDGDVVF NLATCFRADG LPVAPQRGQA 

      1090       1100       1110       1120       1130       1140 
EVRAKAGQAR VKQESVGVFA CKNKWQPDDV TESLPPKKMK CGKEKDSEEQ QLQPQAKAVV 

      1150       1160       1170       1180       1190       1200 
RSSHRPKCRK LPSDPQESTK KSPRGASDSG KEHNGVRGKH KHRKPTKPES QSPGKRADSH 

      1210       1220       1230       1240       1250       1260 
EEGSLEKKAK SSFRDFIPVV LSTRTRSQSG SICSSFAGMA DSDMGSQEVF PTEEEEEVTP 

      1270       1280       1290       1300       1310       1320 
TPAKRRKVRK TQRDTQYRSH HAQDKSLLSQ GRRHLWRARE MPWRTEAARQ MWDTNEEEEE 

      1330       1340       1350       1360       1370       1380 
EEEEGLLKRK KRRRQKSRKY QTGEYLTEQE DEQRRKGRAD LKARKQKTSS SQSLEHRLRN 

      1390       1400       1410       1420       1430       1440 
RNLLLPNKVQ GISDSPNGFL PNNLEEPACL ENSEKPSGKR KCKTKHMATV SEEAKDVVLY 

      1450       1460       1470       1480       1490       1500 
CLQKDSEDVN HRDNAGYTAL HEACSRGWTD ILNILLEHGA NVNCSAQDGT RPVHDAVVND 

      1510       1520       1530       1540       1550       1560 
NLETIWLLLS YGADPTLATY SGQTAMKLAS SDTMKRFLSD HLSDLQGRAE GDPGVSWDFY 

      1570       1580       1590       1600       1610       1620 
SSSVLEEKDG FACDLLHNPP GSSDQEGDDP MEEDDFMFEL SDKPLLPCYN LQVSVSRGPC 

      1630       1640       1650       1660       1670       1680 
NWFLFSDVLK RLKLSSRIFQ ARFPHFEITT MPKAEFYRQV ASSQLLTPAE RPGGLDDRSP 

      1690       1700       1710 
PGSSETVELV RYEPDLLRLL GSEVEFQSCN S 

« Hide

Isoform 2 [UniParc].

Checksum: 08F656081607E8C7
Show »

FASTA1,581166,958
Isoform 3 [UniParc].

Checksum: 28D139925EE1E2CD
Show »

FASTA1,785190,595

References

« Hide 'large scale' references
[1]"The DNA sequence of the human X chromosome."
Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. expand/collapse author list , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
[2]"Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones."
Jikuya H., Takano J., Kikuno R., Hirosawa M., Nagase T., Nomura N., Ohara O.
DNA Res. 10:49-57(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 16-1711 (ISOFORM 1), VARIANT LEU-111.
Tissue: Spleen.
[3]Rhodes S.
Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 566-1435 (ISOFORM 2).
[4]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1265-1711 (ISOFORM 2).
Tissue: Amygdala.
[5]"A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP."
Pagan J.K., Arnold J., Hanchard K.J., Kumar R., Bruno T., Jones M.J., Richard D.J., Forrest A., Spurdle A., Verdin E., Crossley M., Fanciulli M., Chenevix-Trench G., Young D.B., Khanna K.K.
J. Biol. Chem. 282:15248-15257(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH CTBP1; HDAC4; HDAC5 AND HDAC7, MUTAGENESIS OF 623-ASP-LEU-624, TISSUE SPECIFICITY.
[6]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-613; SER-1033 AND SER-1162, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1476 (ISOFORM 3), IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
[7]"Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs."
Junco S.E., Wang R., Gaipa J.C., Taylor A.B., Schirf V., Gearhart M.D., Bardwell V.J., Demeler B., Hart P.J., Kim C.A.
Structure 21:665-671(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 1634-1748 IN COMPLEX WITH PCGF1, INTERACTION WITH PCGF1, MUTAGENESIS OF LEU-1665.
[8]"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E.
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANT [LARGE SCALE ANALYSIS] ASP-832.
[9]"Identification of pathogenic gene variants in small families with intellectually disabled siblings by exome sequencing."
Schuurs-Hoeijmakers J.H., Vulto-van Silfhout A.T., Vissers L.E., van de Vondervoort I.I., van Bon B.W., de Ligt J., Gilissen C., Hehir-Kwa J.Y., Neveling K., del Rosario M., Hira G., Reitano S., Vitello A., Failla P., Greco D., Fichera M., Galesi O., Kleefstra T. expand/collapse author list , Greally M.T., Ockeloen C.W., Willemsen M.H., Bongers E.M., Janssen I.M., Pfundt R., Veltman J.A., Romano C., Willemsen M.A., van Bokhoven H., Brunner H.G., de Vries B.B., de Brouwer A.P.
J. Med. Genet. 50:802-811(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANT SER-820.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL034405 Genomic DNA. No translation available.
Z82208, AL136450 Genomic DNA. Translation: CAI42768.1.
Z82208, AL136450 Genomic DNA. Translation: CAI42769.1.
Z82208 Genomic DNA. Translation: CAI42770.1.
AL136450, Z82208 Genomic DNA. Translation: CAI42885.1.
AL136450, Z82208 Genomic DNA. Translation: CAI42884.1.
AK074089 mRNA. Translation: BAB84915.1.
AL096777 mRNA. Translation: CAB46626.1.
AK124676 mRNA. Translation: BAC85922.1. Different initiation.
RefSeqNP_068765.3. NM_021946.4.
UniGeneHs.496748.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4HPMX-ray1.85A/C1594-1711[»]
ProteinModelPortalQ5H9F3.
SMRQ5H9F3. Positions 1429-1577, 1594-1711.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid121961. 12 interactions.
DIPDIP-60148N.
STRING9606.ENSP00000218147.

PTM databases

PhosphoSiteQ5H9F3.

Polymorphism databases

DMDM74762178.

Proteomic databases

PaxDbQ5H9F3.
PRIDEQ5H9F3.

Protocols and materials databases

DNASU63035.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000218147; ENSP00000218147; ENSG00000085185. [Q5H9F3-1]
ENST00000303743; ENSP00000307541; ENSG00000085185. [Q5H9F3-3]
ENST00000359304; ENSP00000352253; ENSG00000085185. [Q5H9F3-2]
ENST00000540052; ENSP00000437775; ENSG00000085185. [Q5H9F3-1]
GeneID63035.
KEGGhsa:63035.
UCSCuc010nrd.1. human. [Q5H9F3-2]
uc022cdu.1. human. [Q5H9F3-1]

Organism-specific databases

CTD63035.
GeneCardsGC0XP129115.
HGNCHGNC:25657. BCORL1.
HPAHPA031775.
HPA031777.
MIM300688. gene.
neXtProtNX_Q5H9F3.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG300696.
HOVERGENHBG104815.
InParanoidQ5H9F3.
OMASPFVIFP.
OrthoDBEOG7KWSGQ.
PhylomeDBQ5H9F3.
TreeFamTF333317.

Gene expression databases

ArrayExpressQ5H9F3.
BgeeQ5H9F3.
CleanExHS_BCORL1.
GenevestigatorQ5H9F3.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamPF12796. Ank_2. 1 hit.
[Graphical view]
SMARTSM00248. ANK. 2 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSBCORL1. human.
GenomeRNAi63035.
NextBio65531.
PROQ5H9F3.
SOURCESearch...

Entry information

Entry nameBCORL_HUMAN
AccessionPrimary (citable) accession number: Q5H9F3
Secondary accession number(s): B5MDQ8 expand/collapse secondary AC list , Q5H9F2, Q5H9F4, Q6ZVE0, Q8TEN3, Q9Y528
Entry history
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: February 15, 2005
Last modified: April 16, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome X

Human chromosome X: entries, gene names and cross-references to MIM