Q5H737A0A484G1I9N4VN37TRMB_COLORtRNA (guanine-N(7)-)-methyltransferase2.1.1.33Appressorial penetration into host protein 1Transfer RNA methyltransferase 8tRNA (guanine(46)-N(7))-methyltransferasetRNA(m7G46)-methyltransferaseTRM8APH1Cob_06482Cob_v002187Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)Cucumber anthracnose fungusColletotrichum lagenariumEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeGlomerellalesGlomerellaceaeColletotrichumColletotrichum orbiculare species complexA gene involved in modifying transfer RNA is required for fungal pathogenicity and stress tolerance of Colletotrichum lagenarium.NUCLEOTIDE SEQUENCE [GENOMIC DNA]DISRUPTION PHENOTYPEComparative genomic and transcriptomic analyses reveal the hemibiotrophic stage shift of Colletotrichum fungi.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Genome sequence resources for four phytopathogenic fungi from the Colletotrichum orbiculare species complex.GENOME REANNOTATIONCatalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteinetRNA modification; N(7)-methylguanine-tRNA biosynthesis.Forms a complex with TRM82.NucleusSignificant reduction in pathogenicity on the host plants. Mutants develop penetration hyphae into cellophane, suggesting that appressoria of the mutants retain basic function for penetration. However, they fail to develop intracellular penetration hyphae into epidermis of the host plants.Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.MethyltransferaseNucleusReference proteomeRNA-bindingS-adenosyl-L-methionineTransferasetRNA processingtRNA-bindingS-adenosyl-L-methionineS-adenosyl-L-methionineS-adenosyl-L-methionineS-adenosyl-L-methionineS-adenosyl-L-methionineMGRARPKSQKRGDYRVSRSQENAAELPKKKFYRQRAHANPFSDHHLVYPACPDEMDWTLYYPAFPTQGETLPNHIFTHNQSCMRISDSTRSGSLQKNIEVVDIGCGFGGLLVALAPLMPETLALGLEIRTSVTEYVQEKIRALRAQNEGTGLYQNIGCIRANSMKFLPNFLRKSQLSKIFICFPDPHFKARKHKARIVSATLNSEYAFALRPGGIVYTITDVEPLHQWMAEHFVAHPSFERLSQEEEEADECVQVMKSETEEGRKVTRNQGQKFVALFRRIEDPPW
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