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Protein

Ribonuclease H

Gene

rnhA

Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9Magnesium 1UniRule annotation1
Metal bindingi9Magnesium 2UniRule annotation1
Metal bindingi47Magnesium 1UniRule annotation1
Metal bindingi69Magnesium 1UniRule annotation1
Metal bindingi133Magnesium 2UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease HUniRule annotation (EC:3.1.26.4UniRule annotation)
Short name:
RNase HUniRule annotation
Gene namesi
Name:rnhAUniRule annotation
Ordered Locus Names:XOO1041
OrganismiXanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Taxonomic identifieri291331 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000006735 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001954241 – 150Ribonuclease HAdd BLAST150

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ5H426.
SMRiQ5H426.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 141RNase HUniRule annotationAdd BLAST141

Sequence similaritiesi

Belongs to the RNase H family.UniRule annotation

Phylogenomic databases

KOiK03469.
OMAiMQEIEIF.

Family and domain databases

CDDicd09278. RNase_HI_prokaryote_like. 1 hit.
Gene3Di3.30.420.10. 1 hit.
HAMAPiMF_00042. RNase_H. 1 hit.
InterProiView protein in InterPro
IPR012337. RNaseH-like_sf.
IPR002156. RNaseH_domain.
IPR036397. RNaseH_sf.
IPR022892. RNaseHI.
PfamiView protein in Pfam
PF00075. RNase_H. 1 hit.
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiView protein in PROSITE
PS50879. RNASE_H. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5H426-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSIEVHTDG SCLGNPGPGG WAALLRYNGR EKELAGGEAV STNNRMELMA
60 70 80 90 100
AIMALETLTE PCEIVLHTDS QYVRQGITEW MPGWVRRNWK TAGGDPVKNR
110 120 130 140 150
ELWERLHAAT QRHRIDWRWV KGHNGDPDNE RVDVLARNQA TAQRDGRATS
Length:150
Mass (Da):16,900
Last modified:March 1, 2005 - v1
Checksum:iADE6FC39E0BB35EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013598 Genomic DNA. Translation: AAW74295.1.

Genome annotation databases

EnsemblBacteriaiAAW74295; AAW74295; XOO1041.
KEGGixoo:XOO1041.

Similar proteinsi

Entry informationi

Entry nameiRNH_XANOR
AccessioniPrimary (citable) accession number: Q5H426
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: March 1, 2005
Last modified: October 25, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome