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Q5H0A0

- GCH4_XANOR

UniProt

Q5H0A0 - GCH4_XANOR

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 2 (12 Apr 2005)
      Previous versions | rss
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    • Comment

    Functioni

    Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei154 – 1541May be catalytically importantUniRule annotation

    GO - Molecular functioni

    1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciXORY291331:GJBV-2215-MONOMER.
    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
    Gene namesi
    Name:folE2UniRule annotation
    Ordered Locus Names:XOO2367
    OrganismiXanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
    Taxonomic identifieri291331 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
    ProteomesiUP000006735: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306GTP cyclohydrolase FolE2PRO_0000147735Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi291331.XOO2367.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5H0A0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase IV family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1469.
    HOGENOMiHOG000247517.
    KOiK09007.
    OrthoDBiEOG6X6RBH.

    Family and domain databases

    HAMAPiMF_01527_B. GTP_cyclohydrol_B.
    InterProiIPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view]
    PfamiPF02649. GCHY-1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5H0A0-1 [UniParc]FASTAAdd to Basket

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    MSATLPDVAV TEAFTLSAPL RWVGMQDIAI PVHLDAASGS GLAARASVQV    50
    DLPRAELKGI HMSRLYRLLD LHLQRPLSPA MLPQLLQALI ESHADCASRA 100
    ARLTLSFALM LRMPALRSEG LSGWRAYPVR IAAQCRAGRT TIQLQVEVLY 150
    ASTCPCSAAL SRQLLSDAFV QQHAWCDALP LQDVAQWLQD HGSYATPHSQ 200
    RSVAQVCVDL PADTQGFAIQ ELIGLCEQAL ATPVQAAVRR PDEQAFARLN 250
    GANLMYVEDA ARRLRKQLAE HYATFHVAVR HLESLHAHDA VAETGSDDET 300
    FFPAAL 306
    Length:306
    Mass (Da):33,383
    Last modified:April 12, 2005 - v2
    Checksum:i7F85C6A280357FCF
    GO

    Sequence cautioni

    The sequence AAW75621.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013598 Genomic DNA. Translation: AAW75621.1. Different initiation.
    RefSeqiYP_201006.1. NC_006834.1.

    Genome annotation databases

    EnsemblBacteriaiAAW75621; AAW75621; XOO2367.
    GeneIDi3261679.
    KEGGixoo:XOO2367.
    PATRICi24104002. VBIXanOry111333_2633.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE013598 Genomic DNA. Translation: AAW75621.1 . Different initiation.
    RefSeqi YP_201006.1. NC_006834.1.

    3D structure databases

    ProteinModelPortali Q5H0A0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 291331.XOO2367.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW75621 ; AAW75621 ; XOO2367 .
    GeneIDi 3261679.
    KEGGi xoo:XOO2367.
    PATRICi 24104002. VBIXanOry111333_2633.

    Phylogenomic databases

    eggNOGi COG1469.
    HOGENOMi HOG000247517.
    KOi K09007.
    OrthoDBi EOG6X6RBH.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .
    BioCyci XORY291331:GJBV-2215-MONOMER.

    Family and domain databases

    HAMAPi MF_01527_B. GTP_cyclohydrol_B.
    InterProi IPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view ]
    Pfami PF02649. GCHY-1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KACC10331 / KXO85.

    Entry informationi

    Entry nameiGCH4_XANOR
    AccessioniPrimary (citable) accession number: Q5H0A0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 12, 2005
    Last sequence update: April 12, 2005
    Last modified: October 1, 2014
    This is version 55 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3