Reviewed, UniProtKB/Swiss-Prot Q5GX78 (DNAE2_XANOR)

Names and origin

Protein names

Recommended name:
    Error-prone DNA polymerase
    EC=2.7.7.7

Gene names

Name:	dnaE2
Ordered Locus Names:	XOO3439

Organism

Xanthomonas oryzae pv. oryzae [Complete proteome] [HAMAP]

Taxonomic identifier

64187 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Xanthomonas

Protein attributes

Sequence length	1083 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity.
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Subcellular location	CytoplasmProbable.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

Ontologies

Keywords
Biological process	DNA damage DNA repair DNA replication
Cellular component	Cytoplasm
Molecular function	DNA-directed DNA polymerase Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: InterPro error-prone DNA repair Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1083	1083	Error-prone DNA polymerase		PRO_0000103407

Sequences

	Sequence		Length	Mass (Da)
	Q5GX78-1 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: 2F19994AA0FB2727	FASTA	1,083	120,455
	10 20 30 40 50 60 MSWDDAIEGV DRDTPGGRMP RAWNVAARLR AANDDISHAH VADGVPTYAE LHCLSDFSFL 70 80 90 100 110 120 RGASSAEQLF ARAQHCGYSA LAITDECSLA GIVRGLEASR VTGVRLIVGS EFTLIDGTRF 130 140 150 160 170 180 VLLVENAHGY PQVCGLVTTA RRAASKGAYR LGRADVEAQF RDVAPGVFAL WLPGVQPQAE 190 200 210 220 230 240 QGAWLQQVFG ERAFLAVELH REQDDGARLQ VLQALAQQLG MTAVASGDVH MAQRRERIVQ 250 260 270 280 290 300 DTLTAIRHTL PLAECGAHLF RNGERHLRTR RALGNIYPDA LLQAAVALAQ RCTFDISKIS 310 320 330 340 350 360 YTYPRELVPE GHTPTSYLRQ LTEAGIRKRW PGGITAKVRE DIEKELALIA LKKYEAFFLT 370 380 390 400 410 420 VQDVVRFARE QNILCQGRGS SANSAVCYAL GITAVNPDET RLLMARFLSE KRDEPPDIDV 430 440 450 460 470 480 DFEHERREEV LQYVYRKYGR ERAALAATVI CYRGKSAVRD VAKAFGLPPD QIALLANCYG 490 500 510 520 530 540 WGNGETPMEQ RIEEAGFDLA NPLINKILLV TEHLRDHPRH LSQHVGGFVI SDEPLSLLVP 550 560 570 580 590 600 VENAAMADRT IIQWDKDDLE TMKLLKVDCL ALGMLTCIRK TLDLVRGHRG RDYSIATLPG 610 620 630 640 650 660 EDLPTYKMIQ RADTVGVFQI ESRAQMAMLP RLKPAEFYDL VIEVAIVRPG PIQGDMVHPY 670 680 690 700 710 720 LRRRQGREDV SYPSPAVEDI LKPTLGVPLF QEQVMELLMH AADYTESEAD NLRRSMAAWR 730 740 750 760 770 780 RGGDMEQHRM RVRERMQGKG YASTFIDQIF EQIKGFGSYG FPQSHAASFA KLVYASCWLK 790 800 810 820 830 840 RHEPAAFACG LLNAQPMGFY SASQIVQDAR RGSPERERVE VLPVDVVHSD WDNTLVGGRP 850 860 870 880 890 900 WRSAADPGEQ PAIRLGMRQV AGLSDVVAQR IVAARTQRAF ADIGDLCLRA ALDEKACLAL 910 920 930 940 950 960 AEAGALQGMV GNRNAARWAM AGVEARRPLL PGSPEERPVA FEAPHAGEEI LADYRSVGLS 970 980 990 1000 1010 1020 LRQHPMALLR PQMRQRRILG LRDLQGRPHG SGVHVAGLVT QRQRPATAKG TIFVTLEDEH 1030 1040 1050 1060 1070 1080 GMINVIVWSH LALRRRRALL ESRLLAVRGR WERVDGVEHL IAGDLHDLSD LLGDMQLPSR DFH

References

[1]

"The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the bacterial blight pathogen of rice." Lee B.-M., Park Y.-J., Park D.-S., Kang H.-W., Kim J.-G., Song E.-S., Park I.-C., Yoon U.-H., Hahn J.-H., Koo B.-S., Lee G.-B., Kim H., Park H.-S., Yoon K.-O., Kim J.-H., Jung C.-H., Koh N.-H., Seo J.-S., Go S.-J. Nucleic Acids Res. 33:577-586(2005) [PubMed: 15673718] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KACC10331 / KXO85.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013598 Genomic DNA. Translation: AAW76693.1.
RefSeq	YP_202078.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3264419.
GenomeReviews	Gene locus XOO3439 in contig AE013598_GR.
KEGG	xoo:XOO3439.
NMPDR	fig|291331.3.peg.3546.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5GX78.
Enzyme and pathway databases
BioCyc	XORY291331:XOO3439-MON.
Family and domain databases
HAMAP	MF_01902. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA_bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. PHP_N. IPR004805. PolC_alpha. [Graphical view]
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DNAE2_XANOR

Accession

Primary (citable) accession number: Q5GX78

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2005
Last sequence update:	March 1, 2005
Last modified:	November 25, 2008
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)