Q5GT73 (Q5GT73_WOLTR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrodipicolinate synthase, DapA EMBL AAW70801.1

Gene names

Ordered Locus Names:

Wbm0210

Organism

Wolbachia sp. subsp. Brugia malayi (strain TRS) [Complete proteome] [HAMAP]

Taxonomic identifier

292805 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Wolbachieae › Wolbachia

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263
Subcellular location	Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Diaminopimelate biosynthesis SAAS SAAS005263 Lysine biosynthesis SAAS SAAS005263
Cellular component	Cytoplasm SAAS SAAS005263
Ligand	Schiff base SAAS SAAS005263
Molecular function	Lyase SAAS SAAS005263
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	diaminopimelate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	dihydrodipicolinate synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5GT73 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: F57B377AAD0F4697	FASTA	267	29,773
	10 20 30 40 50 60 MQAKAENGVV LLGSTGESLS LTDSEKRTLV EFACKLKLNM KIIIGVPGVN LYQTLEWLNF 70 80 90 100 110 120 CKDIPIHGYL MTTPIYTKPG VMGQTLWFEK LLEKAHVPAM FYNIPSRAGV SLHVETVYNL 130 140 150 160 170 180 SSHERFWAIK DSSGTVDTLI EYKKVAPNVE VFCGDDNMIH DMAAYGTAGL VSVASNAWPH 190 200 210 220 230 240 VAHEYVKQCL NGKSFHADVW QQACKALFIA SNPIPTKALL HGIGLIEHRT VRLPLSTQDL 250 260 PSVDEIKKAT EIILNLEKVN YFYHPMV

References

[1]

"The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode." Foster J., Ganatra M., Kamal I., Ware J., Makarova K., Ivanova N., Bhattacharyya A., Kapatral V., Kumar S., Posfai J., Vincze T., Ingram J., Moran L., Lapidus A., Omelchenko M., Kyrpides N., Ghedin E., Wang S. , Goltsman E., Joukov V., Ostrovskaya O., Tsukerman K., Mazur M., Comb D., Koonin E., Slatko B. PLoS Biol. 3:599-614(2005) [PubMed: 15780005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017321 Genomic DNA. Translation: AAW70801.1.
RefSeq	YP_198043.2. NC_006833.1.
3D structure databases
ProteinModelPortal	Q5GT73.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5GT73.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBWOLT00000002952; EBWOLP00000002647; EBWOLG00000002952.
GeneID	3266864.
GenomeReviews	Gene locus Wbm0210 in contig AE017321_GR.
KEGG	wbm:Wbm0210.
PATRIC	24031945. VBIWolEnd7741_0354.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0329.
GeneTree	EBGT00050000031092.
HOGENOM	HBG358848.
OMA	NITATPY.
ProtClustDB	PRK03170.
Enzyme and pathway databases
BioCyc	WPIP80849:WBM0210-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002220. Dihydrodipicolinate_synth-like. IPR020625. Dihydrodipicolinate_synth_AS. IPR020624. Dihydrodipicolinate_synth_CS. IPR005263. Dihydrodipicolinate_synth_DapA. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01714.
PANTHER	PTHR12128. DHDPS. 1 hit.
Pfam	PF00701. DHDPS. 1 hit. [Graphical view]
PIRSF	PIRSF001365. DHDPS. 1 hit.
PRINTS	PR00146. DHPICSNTHASE.
TIGRFAMs	TIGR00674. DapA. 1 hit.
PROSITE	PS00665. DHDPS_1. 1 hit. PS00666. DHDPS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5GT73_WOLTR

Accession

Primary (citable) accession number: Q5GT73

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2005
Last sequence update:	March 1, 2005
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)