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Q5GSU2

- EFTU1_WOLTR

UniProt

Q5GSU2 - EFTU1_WOLTR

Protein

Elongation factor Tu 1

Gene

tuf1

Organism
Wolbachia sp. subsp. Brugia malayi (strain TRS)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Mar 2005)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi26 – 338GTPUniRule annotation
    Nucleotide bindingi83 – 875GTPUniRule annotation
    Nucleotide bindingi138 – 1414GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciWEND292805:GH18-388-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor Tu 1UniRule annotation
    Short name:
    EF-Tu 1UniRule annotation
    Gene namesi
    Name:tuf1UniRule annotation
    Ordered Locus Names:Wbm0343
    OrganismiWolbachia sp. subsp. Brugia malayi (strain TRS)
    Taxonomic identifieri292805 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
    ProteomesiUP000000534: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 399399Elongation factor Tu 1PRO_0000337573Add
    BLAST

    Proteomic databases

    PRIDEiQ5GSU2.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi292805.Wbm0343.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5GSU2.
    SMRiQ5GSU2. Positions 17-396.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini17 – 208192tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni26 – 338G1By similarity
    Regioni62 – 665G2By similarity
    Regioni83 – 864G3By similarity
    Regioni138 – 1414G4By similarity
    Regioni175 – 1773G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiISAPAAC.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5GSU2-1 [UniParc]FASTAAdd to Basket

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    MTTAVEATAQ VVEAFGKPHV NVGTIGHVDH GKTTLTAAIT KHYGNFVAYD    50
    QIDKAPEERK RGITIATAHV EYQTEKRHYA HVDCPGHADY VKNMIVGAAQ 100
    MDAAILVVSG VDGPMPQTRE HILLAKQVGV GYIVVYINKA DVSDPDMIGL 150
    VEMEVRELLS KYGFPGDEVP VVIGSALKAL EDDDGEYGKK SIDKLMERLD 200
    DYVEVPPRSV DLPFLLPIED VFSISGRGTV VTGRIEKGEI KIGDEIEIIG 250
    LKATQKTTCT GVEMFKKLLE KGSAGLNVGI LLRGTKREEV ERGQVLAKPG 300
    TITPHRKFKA EVYILKKEEG GRHTPFFANY QPQFYLRTTD VTGSIKLLEG 350
    KEMVMPGDNV SIEVELQVPI AMDKGLRFAI REGGRTVGSG VVSEILEWV 399
    Length:399
    Mass (Da):43,712
    Last modified:March 1, 2005 - v1
    Checksum:i3814F7364E3118E1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017321 Genomic DNA. Translation: AAW70932.1.
    RefSeqiYP_198174.1. NC_006833.1.

    Genome annotation databases

    EnsemblBacteriaiAAW70932; AAW70932; Wbm0343.
    GeneIDi3266987.
    KEGGiwbm:Wbm0343.
    PATRICi24032317. VBIWolEnd7741_0536.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017321 Genomic DNA. Translation: AAW70932.1 .
    RefSeqi YP_198174.1. NC_006833.1.

    3D structure databases

    ProteinModelPortali Q5GSU2.
    SMRi Q5GSU2. Positions 17-396.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 292805.Wbm0343.

    Proteomic databases

    PRIDEi Q5GSU2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW70932 ; AAW70932 ; Wbm0343 .
    GeneIDi 3266987.
    KEGGi wbm:Wbm0343.
    PATRICi 24032317. VBIWolEnd7741_0536.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi ISAPAAC.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci WEND292805:GH18-388-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TRS.

    Entry informationi

    Entry nameiEFTU1_WOLTR
    AccessioniPrimary (citable) accession number: Q5GSU2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: March 1, 2005
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3