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Q5GRV2

- PGK_WOLTR

UniProt

Q5GRV2 - PGK_WOLTR

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Wolbachia sp. subsp. Brugia malayi (strain TRS)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 70 (01 Oct 2014)
      Sequence version 1 (01 Mar 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei37 – 371SubstrateUniRule annotation
    Binding sitei118 – 1181SubstrateUniRule annotation
    Binding sitei151 – 1511SubstrateUniRule annotation
    Binding sitei201 – 2011ATPUniRule annotation
    Binding sitei322 – 3221ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi352 – 3554ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciWEND292805:GH18-793-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:Wbm0684
    OrganismiWolbachia sp. subsp. Brugia malayi (strain TRS)
    Taxonomic identifieri292805 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeWolbachieaeWolbachia
    ProteomesiUP000000534: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 399399Phosphoglycerate kinasePRO_1000096392Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi292805.Wbm0684.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5GRV2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni22 – 243Substrate bindingUniRule annotation
    Regioni60 – 634Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiMSIRYID.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5GRV2-1 [UniParc]FASTAAdd to Basket

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    MMNIPNIENC DLHGKAVLLR VDFNIPIKNG KVHDATRVLR SLPTIRHLVN    50
    AGAKVIIISH FGRPRAKDNN LSLKNVVKTL SQLLNKEVKF VDDCIGKKVQ 100
    KVVNAIAIRD VILLENLRFY KEEEQNDANF AKQLASLADV YVNDAFSCSH 150
    RAHASISRIT EFLPSYAGFC LQDELRYLEK AVSFEAKPIT AIVGGAKIST 200
    KIKMLIRLAE KVDYLVLGGA IANNFLLFNK VNIGKSFFQN GVDSLLHDVV 250
    KIADKNNCKI VIPEDVLIAV NSDYSTCILR KTESVLDNDV ILDIGPQTLS 300
    TISSIVASSK ALLWNGPIGV FEHSAFANGT IEVMKVVSDS THKGKLTSVI 350
    GGGDSLSAIN AAGLTDKDFT YVSTGGGAFL SWLSGDKMPG IAALQSMLN 399
    Length:399
    Mass (Da):43,398
    Last modified:March 1, 2005 - v1
    Checksum:i890AE5E64AC2D999
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017321 Genomic DNA. Translation: AAW71272.1.
    RefSeqiWP_011256881.1. NC_006833.1.
    YP_198514.1. NC_006833.1.

    Genome annotation databases

    EnsemblBacteriaiAAW71272; AAW71272; Wbm0684.
    GeneIDi3266961.
    KEGGiwbm:Wbm0684.
    PATRICi24033507. VBIWolEnd7741_1112.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017321 Genomic DNA. Translation: AAW71272.1 .
    RefSeqi WP_011256881.1. NC_006833.1.
    YP_198514.1. NC_006833.1.

    3D structure databases

    ProteinModelPortali Q5GRV2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 292805.Wbm0684.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW71272 ; AAW71272 ; Wbm0684 .
    GeneIDi 3266961.
    KEGGi wbm:Wbm0684.
    PATRICi 24033507. VBIWolEnd7741_1112.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi MSIRYID.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci WEND292805:GH18-793-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TRS.

    Entry informationi

    Entry nameiPGK_WOLTR
    AccessioniPrimary (citable) accession number: Q5GRV2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: March 1, 2005
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3