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Protein

XK-related protein 9

Gene

XKR9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Protein family/group databases

TCDBi2.A.112.1.12. 2.a.112. the kx blood-group antigen (kxa) family.

Names & Taxonomyi

Protein namesi
Recommended name:
XK-related protein 9
Gene namesi
Name:XKR9
Synonyms:XRG9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:20937. XKR9.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2821HelicalSequence analysisAdd
BLAST
Transmembranei38 – 5821HelicalSequence analysisAdd
BLAST
Transmembranei166 – 18621HelicalSequence analysisAdd
BLAST
Transmembranei203 – 22321HelicalSequence analysisAdd
BLAST
Transmembranei224 – 24421HelicalSequence analysisAdd
BLAST
Transmembranei256 – 27621HelicalSequence analysisAdd
BLAST
Transmembranei295 – 31521HelicalSequence analysisAdd
BLAST
Transmembranei318 – 33821HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670567.

Polymorphism and mutation databases

BioMutaiXKR9.
DMDMi74707815.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 373373XK-related protein 9PRO_0000190796Add
BLAST

Proteomic databases

PaxDbiQ5GH70.
PeptideAtlasiQ5GH70.
PRIDEiQ5GH70.

PTM databases

iPTMnetiQ5GH70.

Expressioni

Gene expression databases

BgeeiQ5GH70.
CleanExiHS_XKR9.
ExpressionAtlasiQ5GH70. baseline and differential.

Organism-specific databases

HPAiHPA044430.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000386141.

Structurei

3D structure databases

ProteinModelPortaliQ5GH70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XK family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4790. Eukaryota.
ENOG410YRUD. LUCA.
GeneTreeiENSGT00530000062854.
HOGENOMiHOG000060276.
HOVERGENiHBG055839.
InParanoidiQ5GH70.
OMAiLVVQCFS.
PhylomeDBiQ5GH70.
TreeFamiTF316454.

Family and domain databases

InterProiIPR018629. XK_fam.
[Graphical view]
PfamiPF09815. XK-related. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5GH70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKYTKQNFMM SVLGIIIYVT DLIVDIWVSV RFFHEGQYVF SALALSFMLF
60 70 80 90 100
GTLVAQCFSY SWFKADLKKA GQESQHCFLL LHCLQGGVFT RYWFALKRGY
110 120 130 140 150
HAAFKYDSNT SNFVEEQIDL HKEVIDRVTD LSMLRLFETY LEGCPQLILQ
160 170 180 190 200
LYILLEHGQA NFSQYAAIMV SCCAISWSTV DYQVALRKSL PDKKLLNGLC
210 220 230 240 250
PKITYLFYKL FTLLSWMLSV VLLLFLNVKI ALFLLLFLWL LGIIWAFKNN
260 270 280 290 300
TQFCTCISME FLYRIVVGFI LIFTFFNIKG QNTKCPMSCY YIVRVLGTLG
310 320 330 340 350
ILTVFWVCPL TIFNPDYFIP ISITIVLTLL LGILFLIVYY GSFHPNRSAE
360 370
TKCDEIDGKP VLRECRMRYF LME
Length:373
Mass (Da):43,406
Last modified:March 1, 2005 - v1
Checksum:iE6B9AF692FED626D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY534247 mRNA. Translation: AAT07096.1.
BC137104 mRNA. Translation: AAI37105.1.
BC137105 mRNA. Translation: AAI37106.1.
CCDSiCCDS34905.1.
RefSeqiNP_001011720.1. NM_001011720.1.
NP_001274187.1. NM_001287258.1.
NP_001274188.1. NM_001287259.1.
NP_001274189.1. NM_001287260.1.
XP_011515826.1. XM_011517524.1.
XP_011515827.1. XM_011517525.1.
UniGeneiHs.458938.

Genome annotation databases

EnsembliENST00000408926; ENSP00000386141; ENSG00000221947.
ENST00000520030; ENSP00000431088; ENSG00000221947.
GeneIDi389668.
KEGGihsa:389668.
UCSCiuc003xyq.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY534247 mRNA. Translation: AAT07096.1.
BC137104 mRNA. Translation: AAI37105.1.
BC137105 mRNA. Translation: AAI37106.1.
CCDSiCCDS34905.1.
RefSeqiNP_001011720.1. NM_001011720.1.
NP_001274187.1. NM_001287258.1.
NP_001274188.1. NM_001287259.1.
NP_001274189.1. NM_001287260.1.
XP_011515826.1. XM_011517524.1.
XP_011515827.1. XM_011517525.1.
UniGeneiHs.458938.

3D structure databases

ProteinModelPortaliQ5GH70.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000386141.

Protein family/group databases

TCDBi2.A.112.1.12. 2.a.112. the kx blood-group antigen (kxa) family.

PTM databases

iPTMnetiQ5GH70.

Polymorphism and mutation databases

BioMutaiXKR9.
DMDMi74707815.

Proteomic databases

PaxDbiQ5GH70.
PeptideAtlasiQ5GH70.
PRIDEiQ5GH70.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000408926; ENSP00000386141; ENSG00000221947.
ENST00000520030; ENSP00000431088; ENSG00000221947.
GeneIDi389668.
KEGGihsa:389668.
UCSCiuc003xyq.3. human.

Organism-specific databases

CTDi389668.
GeneCardsiXKR9.
HGNCiHGNC:20937. XKR9.
HPAiHPA044430.
neXtProtiNX_Q5GH70.
PharmGKBiPA142670567.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4790. Eukaryota.
ENOG410YRUD. LUCA.
GeneTreeiENSGT00530000062854.
HOGENOMiHOG000060276.
HOVERGENiHBG055839.
InParanoidiQ5GH70.
OMAiLVVQCFS.
PhylomeDBiQ5GH70.
TreeFamiTF316454.

Miscellaneous databases

GenomeRNAii389668.
PROiQ5GH70.

Gene expression databases

BgeeiQ5GH70.
CleanExiHS_XKR9.
ExpressionAtlasiQ5GH70. baseline and differential.

Family and domain databases

InterProiIPR018629. XK_fam.
[Graphical view]
PfamiPF09815. XK-related. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A superfamily of XK-related genes (XRG) widely expressed in vertebrates and invertebrates."
    Huang C.-H., Chen Y.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiXKR9_HUMAN
AccessioniPrimary (citable) accession number: Q5GH70
Secondary accession number(s): B2RNS9, B9EH74
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: March 1, 2005
Last modified: July 6, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.