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Q5GAM7

- RNS13_MOUSE

UniProt

Q5GAM7 - RNS13_MOUSE

Protein

Probable inactive ribonuclease-like protein 13

Gene

Rnase13

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Mar 2005)
      Previous versions | rss
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    Functioni

    Does not exhibit any ribonuclease activity.Curated

    GO - Molecular functioni

    1. endoribonuclease activity, producing 3'-phosphomonoesters Source: InterPro
    2. nucleic acid binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable inactive ribonuclease-like protein 13
    Gene namesi
    Name:Rnase13
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:3528592. Rnase13.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Sequence AnalysisAdd
    BLAST
    Chaini23 – 153131Probable inactive ribonuclease-like protein 13PRO_0000308706Add
    BLAST

    Proteomic databases

    PRIDEiQ5GAM7.

    PTM databases

    PhosphoSiteiQ5GAM7.

    Expressioni

    Gene expression databases

    CleanExiMM_RNASE13.
    GenevestigatoriQ5GAM7.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000087203.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5GAM7.
    SMRiQ5GAM7. Positions 25-140.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pancreatic ribonuclease family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG80038.
    GeneTreeiENSGT00390000015830.
    HOGENOMiHOG000008687.
    HOVERGENiHBG095659.
    InParanoidiQ5GAM7.
    OMAiRLYLLCS.
    OrthoDBiEOG78H3VP.
    PhylomeDBiQ5GAM7.
    TreeFamiTF343810.

    Family and domain databases

    Gene3Di3.10.130.10. 1 hit.
    InterProiIPR001427. RNaseA.
    IPR023412. RNaseA_domain.
    [Graphical view]
    PANTHERiPTHR11437. PTHR11437. 1 hit.
    PfamiPF00074. RnaseA. 1 hit.
    [Graphical view]
    ProDomiPD000535. RNaseA. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF54076. SSF54076. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q5GAM7-1 [UniParc]FASTAAdd to Basket

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    MAPDVAWLLV LPLVFRPTLV TGITIQTAIK NFRTLHVDYP MVNYPKGFHG    50
    YCNGLMAYVR GKLQDWYCPK IHYVVHAPLE DIQKFCKYSE SFCENYNEYC 100
    TLTQNSFPVT ICTLVHQQAP TSCSYNSTLT NQRLYLLCSR KHDAEPIGII 150
    GLY 153
    Length:153
    Mass (Da):17,592
    Last modified:March 1, 2005 - v1
    Checksum:iAE5215027F005AC8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY665825 Genomic DNA. Translation: AAV87192.1.
    BC132614 mRNA. Translation: AAI32615.1.
    BC132616 mRNA. Translation: AAI32617.1.
    CCDSiCCDS27048.1.
    RefSeqiNP_001011687.1. NM_001011687.2.
    XP_006519281.1. XM_006519218.1.
    XP_006519282.1. XM_006519219.1.
    XP_006534720.1. XM_006534657.1.
    XP_006534721.1. XM_006534658.1.
    UniGeneiMm.378602.

    Genome annotation databases

    EnsembliENSMUST00000089771; ENSMUSP00000087203; ENSMUSG00000068392.
    GeneIDi497071.
    KEGGimmu:497071.
    UCSCiuc007tnn.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY665825 Genomic DNA. Translation: AAV87192.1 .
    BC132614 mRNA. Translation: AAI32615.1 .
    BC132616 mRNA. Translation: AAI32617.1 .
    CCDSi CCDS27048.1.
    RefSeqi NP_001011687.1. NM_001011687.2.
    XP_006519281.1. XM_006519218.1.
    XP_006519282.1. XM_006519219.1.
    XP_006534720.1. XM_006534657.1.
    XP_006534721.1. XM_006534658.1.
    UniGenei Mm.378602.

    3D structure databases

    ProteinModelPortali Q5GAM7.
    SMRi Q5GAM7. Positions 25-140.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000087203.

    PTM databases

    PhosphoSitei Q5GAM7.

    Proteomic databases

    PRIDEi Q5GAM7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000089771 ; ENSMUSP00000087203 ; ENSMUSG00000068392 .
    GeneIDi 497071.
    KEGGi mmu:497071.
    UCSCi uc007tnn.2. mouse.

    Organism-specific databases

    CTDi 440163.
    MGIi MGI:3528592. Rnase13.

    Phylogenomic databases

    eggNOGi NOG80038.
    GeneTreei ENSGT00390000015830.
    HOGENOMi HOG000008687.
    HOVERGENi HBG095659.
    InParanoidi Q5GAM7.
    OMAi RLYLLCS.
    OrthoDBi EOG78H3VP.
    PhylomeDBi Q5GAM7.
    TreeFami TF343810.

    Miscellaneous databases

    NextBioi 411776.
    PROi Q5GAM7.
    SOURCEi Search...

    Gene expression databases

    CleanExi MM_RNASE13.
    Genevestigatori Q5GAM7.

    Family and domain databases

    Gene3Di 3.10.130.10. 1 hit.
    InterProi IPR001427. RNaseA.
    IPR023412. RNaseA_domain.
    [Graphical view ]
    PANTHERi PTHR11437. PTHR11437. 1 hit.
    Pfami PF00074. RnaseA. 1 hit.
    [Graphical view ]
    ProDomi PD000535. RNaseA. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF54076. SSF54076. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories."
      Cho S., Beintema J.J., Zhang J.
      Genomics 85:208-220(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: C57BL/6J.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain.

    Entry informationi

    Entry nameiRNS13_MOUSE
    AccessioniPrimary (citable) accession number: Q5GAM7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: March 1, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3