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Protein

Probable inactive ribonuclease-like protein 13

Gene

Rnase13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Does not exhibit any ribonuclease activity.Curated

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Probable inactive ribonuclease-like protein 13
Gene namesi
Name:Rnase13
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:3528592. Rnase13.

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 153131Probable inactive ribonuclease-like protein 13PRO_0000308706Add
BLAST

Proteomic databases

PRIDEiQ5GAM7.

PTM databases

PhosphoSiteiQ5GAM7.

Expressioni

Gene expression databases

CleanExiMM_RNASE13.
GenevestigatoriQ5GAM7.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000087203.

Structurei

3D structure databases

ProteinModelPortaliQ5GAM7.
SMRiQ5GAM7. Positions 25-140.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pancreatic ribonuclease family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG80038.
GeneTreeiENSGT00390000015830.
HOGENOMiHOG000008687.
HOVERGENiHBG095659.
InParanoidiQ5GAM7.
OMAiFQGYCNG.
OrthoDBiEOG78H3VP.
PhylomeDBiQ5GAM7.
TreeFamiTF343810.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiIPR029739. RNASE13.
IPR001427. RNaseA.
IPR023412. RNaseA_domain.
[Graphical view]
PANTHERiPTHR11437. PTHR11437. 1 hit.
PTHR11437:SF11. PTHR11437:SF11. 1 hit.
PfamiPF00074. RnaseA. 1 hit.
[Graphical view]
ProDomiPD000535. RNaseA. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54076. SSF54076. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5GAM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPDVAWLLV LPLVFRPTLV TGITIQTAIK NFRTLHVDYP MVNYPKGFHG
60 70 80 90 100
YCNGLMAYVR GKLQDWYCPK IHYVVHAPLE DIQKFCKYSE SFCENYNEYC
110 120 130 140 150
TLTQNSFPVT ICTLVHQQAP TSCSYNSTLT NQRLYLLCSR KHDAEPIGII

GLY
Length:153
Mass (Da):17,592
Last modified:February 28, 2005 - v1
Checksum:iAE5215027F005AC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY665825 Genomic DNA. Translation: AAV87192.1.
BC132614 mRNA. Translation: AAI32615.1.
BC132616 mRNA. Translation: AAI32617.1.
CCDSiCCDS27048.1.
RefSeqiNP_001011687.1. NM_001011687.2.
XP_006519281.1. XM_006519218.1.
XP_006519282.1. XM_006519219.1.
XP_006534720.1. XM_006534657.2.
XP_006534721.1. XM_006534658.2.
UniGeneiMm.378602.

Genome annotation databases

EnsembliENSMUST00000089771; ENSMUSP00000087203; ENSMUSG00000068392.
GeneIDi497071.
KEGGimmu:497071.
UCSCiuc007tnn.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY665825 Genomic DNA. Translation: AAV87192.1.
BC132614 mRNA. Translation: AAI32615.1.
BC132616 mRNA. Translation: AAI32617.1.
CCDSiCCDS27048.1.
RefSeqiNP_001011687.1. NM_001011687.2.
XP_006519281.1. XM_006519218.1.
XP_006519282.1. XM_006519219.1.
XP_006534720.1. XM_006534657.2.
XP_006534721.1. XM_006534658.2.
UniGeneiMm.378602.

3D structure databases

ProteinModelPortaliQ5GAM7.
SMRiQ5GAM7. Positions 25-140.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000087203.

PTM databases

PhosphoSiteiQ5GAM7.

Proteomic databases

PRIDEiQ5GAM7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000089771; ENSMUSP00000087203; ENSMUSG00000068392.
GeneIDi497071.
KEGGimmu:497071.
UCSCiuc007tnn.2. mouse.

Organism-specific databases

CTDi440163.
MGIiMGI:3528592. Rnase13.

Phylogenomic databases

eggNOGiNOG80038.
GeneTreeiENSGT00390000015830.
HOGENOMiHOG000008687.
HOVERGENiHBG095659.
InParanoidiQ5GAM7.
OMAiFQGYCNG.
OrthoDBiEOG78H3VP.
PhylomeDBiQ5GAM7.
TreeFamiTF343810.

Miscellaneous databases

NextBioi411776.
PROiQ5GAM7.
SOURCEiSearch...

Gene expression databases

CleanExiMM_RNASE13.
GenevestigatoriQ5GAM7.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiIPR029739. RNASE13.
IPR001427. RNaseA.
IPR023412. RNaseA_domain.
[Graphical view]
PANTHERiPTHR11437. PTHR11437. 1 hit.
PTHR11437:SF11. PTHR11437:SF11. 1 hit.
PfamiPF00074. RnaseA. 1 hit.
[Graphical view]
ProDomiPD000535. RNaseA. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54076. SSF54076. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories."
    Cho S., Beintema J.J., Zhang J.
    Genomics 85:208-220(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiRNS13_MOUSE
AccessioniPrimary (citable) accession number: Q5GAM7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 22, 2007
Last sequence update: February 28, 2005
Last modified: March 31, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.