Q5GAM7 (RNS13_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable inactive ribonuclease-like protein 13

Gene names

Name:

Rnase13

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	153 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Does not exhibit any ribonuclease activity Potential.
Subcellular location	Secreted Probable.
Sequence similarities	Belongs to the pancreatic ribonuclease family.

Ontologies

Keywords
Cellular component	Secreted
Domain	Signal
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nucleic acid binding Inferred from electronic annotation. Source: InterPro pancreatic ribonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Chain	23 – 153	131	Probable inactive ribonuclease-like protein 13		PRO_0000308706

Sequences

	Sequence		Length	Mass (Da)
	Q5GAM7 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: AE5215027F005AC8	FASTA	153	17,592
	10 20 30 40 50 60 MAPDVAWLLV LPLVFRPTLV TGITIQTAIK NFRTLHVDYP MVNYPKGFHG YCNGLMAYVR 70 80 90 100 110 120 GKLQDWYCPK IHYVVHAPLE DIQKFCKYSE SFCENYNEYC TLTQNSFPVT ICTLVHQQAP 130 140 150 TSCSYNSTLT NQRLYLLCSR KHDAEPIGII GLY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories." Cho S., Beintema J.J., Zhang J. Genomics 85:208-220(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: C57BL/6J.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY665825 Genomic DNA. Translation: AAV87192.1. BC132614 mRNA. Translation: AAI32615.1. BC132616 mRNA. Translation: AAI32617.1.
IPI	IPI00553291.
RefSeq	NP_001011687.1. NM_001011687.2.
UniGene	Mm.378602.
3D structure databases
ProteinModelPortal	Q5GAM7.
SMR	Q5GAM7. Positions 26-152.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000087203.
PTM databases
PhosphoSite	Q5GAM7.
Proteomic databases
PRIDE	Q5GAM7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000089771; ENSMUSP00000087203; ENSMUSG00000068392.
GeneID	497071.
KEGG	mmu:497071.
UCSC	uc007tnn.2. mouse.
Organism-specific databases
CTD	440163.
MGI	MGI:3528592. Rnase13.
Phylogenomic databases
eggNOG	NOG80038.
GeneTree	ENSGT00390000015830.
HOGENOM	HOG000008687.
HOVERGEN	HBG095659.
InParanoid	Q5GAM7.
OMA	FQGYCNG.
OrthoDB	EOG4W0XFF.
Gene expression databases
CleanEx	MM_RNASE13.
Genevestigator	Q5GAM7.
Family and domain databases
Gene3D	3.10.130.10. 1 hit.
InterPro	IPR001427. RNaseA. IPR023412. RNaseA_domain. [Graphical view]
PANTHER	PTHR11437. PTHR11437. 1 hit.
Pfam	PF00074. RnaseA. 1 hit. [Graphical view]
ProDom	PD000535. RNaseA. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF54076. RNaseA. 1 hit.
ProtoNet	Search...
Other
NextBio	411776.
SOURCE	Search...

Entry information

Entry name

RNS13_MOUSE

Accession

Primary (citable) accession number: Q5GAM7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	March 1, 2005
Last modified:	April 3, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program