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Q5GAM2

- Q5GAM2_RAT

UniProt

Q5GAM2 - Q5GAM2_RAT

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Protein
Submitted name: Protein Rnase17
Gene
Rnase17, R17
Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. endoribonuclease activity, producing 3'-phosphomonoesters Source: InterPro
  2. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

EndonucleaseUniRule annotationSAAS annotations, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Rnase17Imported
Submitted name:
Ribonuclease 17Imported
Gene namesi
Name:Rnase17Imported
Synonyms:R17Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 15

Organism-specific databases

RGDi1359245. Rnase17.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

GenevestigatoriQ5GAM2.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050225.

Structurei

3D structure databases

ProteinModelPortaliQ5GAM2.
SMRiQ5GAM2. Positions 26-155.

Family & Domainsi

Sequence similaritiesi

Belongs to the pancreatic ribonuclease family.UniRule annotation

Phylogenomic databases

eggNOGiNOG118739.
GeneTreeiENSGT00390000007840.
HOGENOMiHOG000276882.
HOVERGENiHBG008396.
InParanoidiQ5GAM2.
OMAiNISRNCH.
OrthoDBiEOG7KDFCP.
TreeFamiTF333393.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiIPR001427. RNaseA.
IPR023411. RNaseA_AS.
IPR023412. RNaseA_domain.
[Graphical view]
PANTHERiPTHR11437. PTHR11437. 1 hit.
PfamiPF00074. RnaseA. 1 hit.
[Graphical view]
PRINTSiPR00794. RIBONUCLEASE.
ProDomiPD000535. RNaseA. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00092. RNAse_Pc. 1 hit.
[Graphical view]
SUPFAMiSSF54076. SSF54076. 1 hit.
PROSITEiPS00127. RNASE_PANCREATIC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5GAM2-1 [UniParc]FASTAAdd to Basket

« Hide

MGLKLLESRL CLLLLLGLVL MLASCQPPTP SQWFEIQHIY NRAYPRCNDA    50
MRHRNRFTRH CKDKNTFLHT SFASVVGVCG NRNIPCRNRR YRNCHNSPYR 100
VSITFCNLTT PARIYTQCRY QTTRSRKFYT VGCDPRTPRD SPMYPVVPVH 150
LDRIF 155
Length:155
Mass (Da):18,242
Last modified:March 1, 2005 - v1
Checksum:iBE683A340881B12A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06082831 Genomic DNA. No translation available.
AY665830 Genomic DNA. Translation: AAV87197.1.
RefSeqiNP_001012232.1. NM_001012232.1.
XP_006251959.1. XM_006251897.1.
UniGeneiRn.142436.

Genome annotation databases

EnsembliENSRNOT00000048941; ENSRNOP00000050225; ENSRNOG00000050295.
GeneIDi497195.
KEGGirno:497195.
UCSCiRGD:1359245. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AABR06082831 Genomic DNA. No translation available.
AY665830 Genomic DNA. Translation: AAV87197.1 .
RefSeqi NP_001012232.1. NM_001012232.1.
XP_006251959.1. XM_006251897.1.
UniGenei Rn.142436.

3D structure databases

ProteinModelPortali Q5GAM2.
SMRi Q5GAM2. Positions 26-155.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000050225.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000048941 ; ENSRNOP00000050225 ; ENSRNOG00000050295 .
GeneIDi 497195.
KEGGi rno:497195.
UCSCi RGD:1359245. rat.

Organism-specific databases

CTDi 497195.
RGDi 1359245. Rnase17.

Phylogenomic databases

eggNOGi NOG118739.
GeneTreei ENSGT00390000007840.
HOGENOMi HOG000276882.
HOVERGENi HBG008396.
InParanoidi Q5GAM2.
OMAi NISRNCH.
OrthoDBi EOG7KDFCP.
TreeFami TF333393.

Miscellaneous databases

NextBioi 697703.

Gene expression databases

Genevestigatori Q5GAM2.

Family and domain databases

Gene3Di 3.10.130.10. 1 hit.
InterProi IPR001427. RNaseA.
IPR023411. RNaseA_AS.
IPR023412. RNaseA_domain.
[Graphical view ]
PANTHERi PTHR11437. PTHR11437. 1 hit.
Pfami PF00074. RnaseA. 1 hit.
[Graphical view ]
PRINTSi PR00794. RIBONUCLEASE.
ProDomi PD000535. RNaseA. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00092. RNAse_Pc. 1 hit.
[Graphical view ]
SUPFAMi SSF54076. SSF54076. 1 hit.
PROSITEi PS00127. RNASE_PANCREATIC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Rat Genome Sequencing Project Consortium
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Brown NorwayImported.
  2. "The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories."
    Cho S., Beintema J.J., Zhang J.
    Genomics 85:208-220(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Ensembl
    Submitted (JUN-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Brown NorwayImported.

Entry informationi

Entry nameiQ5GAM2_RAT
AccessioniPrimary (citable) accession number: Q5GAM2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: September 3, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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