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Protein
Submitted name:

Ribonuclease 17

Gene

Rnase17

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Enzyme and pathway databases

ReactomeiR-RNO-6798695. Neutrophil degranulation.
R-RNO-6803157. Antimicrobial peptides.

Names & Taxonomyi

Protein namesi
Submitted name:
Ribonuclease 17Imported
Gene namesi
Name:Rnase17Imported
Synonyms:R17Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi1359245. Rnase17.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25UniRule annotationAdd BLAST25
ChainiPRO_500936880226 – 155UniRule annotationAdd BLAST130

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000050295.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050225.

Structurei

3D structure databases

ProteinModelPortaliQ5GAM2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 155RNAse_PcInterPro annotationAdd BLAST129

Sequence similaritiesi

Belongs to the pancreatic ribonuclease family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410JDT3. Eukaryota.
ENOG411136R. LUCA.
GeneTreeiENSGT00840000129759.
HOGENOMiHOG000276882.
HOVERGENiHBG008396.
OMAiNQSIRCP.
OrthoDBiEOG091G0SFK.
TreeFamiTF333393.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiView protein in InterPro
IPR001427. RNaseA.
IPR023411. RNaseA_AS.
IPR023412. RNaseA_domain.
PANTHERiPTHR11437. PTHR11437. 1 hit.
PfamiView protein in Pfam
PF00074. RnaseA. 1 hit.
PRINTSiPR00794. RIBONUCLEASE.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000535. RNaseA. 1 hit.
SMARTiView protein in SMART
SM00092. RNAse_Pc. 1 hit.
SUPFAMiSSF54076. SSF54076. 1 hit.
PROSITEiView protein in PROSITE
PS00127. RNASE_PANCREATIC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5GAM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLKLLESRL CLLLLLGLVL MLASCQPPTP SQWFEIQHIY NRAYPRCNDA
60 70 80 90 100
MRHRNRFTRH CKDKNTFLHT SFASVVGVCG NRNIPCRNRR YRNCHNSPYR
110 120 130 140 150
VSITFCNLTT PARIYTQCRY QTTRSRKFYT VGCDPRTPRD SPMYPVVPVH

LDRIF
Length:155
Mass (Da):18,242
Last modified:March 1, 2005 - v1
Checksum:iBE683A340881B12A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC094516 Genomic DNA. No translation available.
AY665830 Genomic DNA. Translation: AAV87197.1.
RefSeqiNP_001012232.1. NM_001012232.1.
XP_008768783.1. XM_008770561.1.
UniGeneiRn.142436.

Genome annotation databases

EnsembliENSRNOT00000048941; ENSRNOP00000050225; ENSRNOG00000050295.
GeneIDi497195.
KEGGirno:497195.
UCSCiRGD:1359245. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC094516 Genomic DNA. No translation available.
AY665830 Genomic DNA. Translation: AAV87197.1.
RefSeqiNP_001012232.1. NM_001012232.1.
XP_008768783.1. XM_008770561.1.
UniGeneiRn.142436.

3D structure databases

ProteinModelPortaliQ5GAM2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000050225.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000048941; ENSRNOP00000050225; ENSRNOG00000050295.
GeneIDi497195.
KEGGirno:497195.
UCSCiRGD:1359245. rat.

Organism-specific databases

CTDi497195.
RGDi1359245. Rnase17.

Phylogenomic databases

eggNOGiENOG410JDT3. Eukaryota.
ENOG411136R. LUCA.
GeneTreeiENSGT00840000129759.
HOGENOMiHOG000276882.
HOVERGENiHBG008396.
OMAiNQSIRCP.
OrthoDBiEOG091G0SFK.
TreeFamiTF333393.

Enzyme and pathway databases

ReactomeiR-RNO-6798695. Neutrophil degranulation.
R-RNO-6803157. Antimicrobial peptides.

Gene expression databases

BgeeiENSRNOG00000050295.

Family and domain databases

Gene3Di3.10.130.10. 1 hit.
InterProiView protein in InterPro
IPR001427. RNaseA.
IPR023411. RNaseA_AS.
IPR023412. RNaseA_domain.
PANTHERiPTHR11437. PTHR11437. 1 hit.
PfamiView protein in Pfam
PF00074. RnaseA. 1 hit.
PRINTSiPR00794. RIBONUCLEASE.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD000535. RNaseA. 1 hit.
SMARTiView protein in SMART
SM00092. RNAse_Pc. 1 hit.
SUPFAMiSSF54076. SSF54076. 1 hit.
PROSITEiView protein in PROSITE
PS00127. RNASE_PANCREATIC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5GAM2_RAT
AccessioniPrimary (citable) accession number: Q5GAM2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: April 12, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.