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Protein
Submitted name:

Zbtb7b protein

Gene

Zbtb7b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. metal ion binding Source: InterPro
  3. protein homodimerization activity Source: MGI
  4. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. positive regulation of gene expression Source: MGI
  2. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  3. regulation of CD4-positive, alpha-beta T cell differentiation Source: MGI
  4. regulation of CD8-positive, alpha-beta T cell differentiation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Zbtb7b proteinImported
Gene namesi
Name:Zbtb7bImported
Synonyms:ThpokImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:102755. Zbtb7b.

Subcellular locationi

GO - Cellular componenti

  1. nucleoplasm Source: MGI
  2. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ5FWV9.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103056.

Structurei

3D structure databases

ProteinModelPortaliQ5FWV9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000082521.
HOVERGENiHBG059461.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5FWV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
EGGGGTVMGT GGGGTASGGA GAGVCELDFV GPEALGALLE FAYTATLTTS
60 70 80 90 100
SANMPAVLQA ARLLEIPCVI AACMEILQGS GLEAPSPDED DCERARQYLE
110 120 130 140 150
AFATATTTAS TSGMPNGEDS PPQVPLLPPP PPPPRPVARR SRKPRKAFLQ
160 170 180 190 200
TKGARANHLV PEAPTVLTHP LTYEEEEMVG RLGNSGGSGL GDSYSPPTGA
210 220 230 240 250
ASPAEGPLNY EVFEGEEEEE EMAYPPGYGL AQSNEPSLSP EELGSDEDPI
260 270 280 290 300
DPDLMAYLSS LHQDALTPGL DGQDKLVRKR RSQMPQECPV CHKIIHGAGK
310 320 330 340 350
LPRHMRTHTG EKPFACEVCG VRFTRNDKLK IHMRKHTGER PYSCPHCPAR
360 370 380 390 400
FLHSYDLKNH MHLHTGDHHL IPCWPRPFQW PPGHLPPLSG SILGAVGHHG

TPSHYTRAP
Length:409
Mass (Da):43,713
Last modified:March 1, 2005 - v1
Checksum:iF98B5B3B52C05E2F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089185 mRNA. Translation: AAH89185.1.
UniGeneiMm.262184.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089185 mRNA. Translation: AAH89185.1.
UniGeneiMm.262184.

3D structure databases

ProteinModelPortaliQ5FWV9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:102755. Zbtb7b.

Phylogenomic databases

HOGENOMiHOG000082521.
HOVERGENiHBG059461.

Miscellaneous databases

ChiTaRSiZbtb7b. mouse.
SOURCEiSearch...

Gene expression databases

GenevestigatoriQ5FWV9.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR011333. BTB/POZ_fold.
IPR013069. BTB_POZ.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: NMRIImported.
    Tissue: Mammary tumor. WAP-Tag model. 5 months oldImported.

Entry informationi

Entry nameiQ5FWV9_MOUSE
AccessioniPrimary (citable) accession number: Q5FWV9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: March 4, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.