Reviewed, UniProtKB/Swiss-Prot Q5FWU3 (ATG9A_RAT)

Names and origin

Protein names

Recommended name:
    Autophagy-related protein 9A
Alternative name(s):
    APG9-like 1

Gene names

Name:	Atg9a
Synonyms:	Apg9l1

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	839 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Plays a role in autophagy By similarity.
Subcellular location	Cytoplasmic vesicle › autophagosome membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the ATG9 family.

Ontologies

Keywords
Biological process	Autophagy Protein transport Transport
Cellular component	Cytoplasmic vesicle Membrane
Domain	Transmembrane
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	autophagy Inferred from expression pattern. Source: RGD protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	autophagic vacuole membrane Inferred from electronic annotation. Source: UniProtKB-SubCell cytoplasmic vesicle Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 839	839	Autophagy-related protein 9A		PRO_0000119823
Regions
	Topological domain	1 – 66	66	Cytoplasmic By similarity
	Transmembrane	67 – 87	21	Potential
	Topological domain	88 – 131	44	Lumenal By similarity
	Transmembrane	132 – 152	21	Potential
	Topological domain	153 – 289	137	Cytoplasmic By similarity
	Transmembrane	290 – 310	21	Potential
	Topological domain	311 – 371	61	Lumenal By similarity
	Transmembrane	372 – 392	21	Potential
	Topological domain	393 – 400	8	Cytoplasmic By similarity
	Transmembrane	401 – 421	21	Potential
	Topological domain	422 – 473	52	Lumenal By similarity
	Transmembrane	474 – 494	21	Potential
	Topological domain	495 – 839	345	Cytoplasmic By similarity
Amino acid modifications
	Modified residue	14	1	Phosphoserine By similarity
	Modified residue	18	1	Phosphoserine By similarity
	Modified residue	656	1	Phosphoserine By similarity
	Modified residue	735	1	Phosphoserine By similarity
	Modified residue	738	1	Phosphoserine By similarity
	Modified residue	741	1	Phosphoserine By similarity
	Modified residue	828	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5FWU3-1 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: 18E9A65B55E03C14	FASTA	839	94,488
	10 20 30 40 50 60 MAQFDTEYQR LEASYSDSPP GEEDLLVHVA EGSKSPWHHI ENLDLFFSRV YNLHQKNGFT 70 80 90 100 110 120 CMLIGEIFEL MQFLFVVAFT TFLVSCVDYD ILFANKMVNH SLHPTEPVKV TLPDAFLPAQ 130 140 150 160 170 180 VCSARIQENG SLITILVIAG VFWIHRLIKF IYNICCYWEI HSFYLHALRI PMSALPYCTW 190 200 210 220 230 240 QEVQARIVQT QKEHQICIHK RELTELDIYH RILRFQNYMV ALVNKSLLPL RFRLPGLGEV 250 260 270 280 290 300 VFFTRGLKYN FELILFWGPG SLFLNEWSLK AEYKRGGQRL ELAQRLSNRI LWIGIANFLL 310 320 330 340 350 360 CPLILIWQIL YAFFSYAEVL KREPGALGAR CWSLYGRCYL RHFNELEHEL QSRLNRGYKP 370 380 390 400 410 420 ASKYMNCFLS PLLTLLAKNG AFFAGSILAV LIALTIYDED VLAVEHVLTT VTLLGVTVTV 430 440 450 460 470 480 CRSFIPDQHM VFCPEQLLRV ILAHIHYMPD HWQGNAHRSQ TRDEFAQLFQ YKAVFILEEL 490 500 510 520 530 540 LSPIVTPLIL IFCLRPRALE IIDFFRNFTV EVVGVGDTCS FAQMDVRQHG HPQWLSGGQT 550 560 570 580 590 600 EASVYQQAED GKTELSLMHF AITNPGWQPP RESTAFLGFL KEQVQRDGAA AGLAQGGLLP 610 620 630 640 650 660 ENALFTSIQS LQSESEPLSL IANVVAGSSC RGPPLSRDLQ GSRHRADVAS ALRSFSPLQP 670 680 690 700 710 720 GQAPQGRVPS TMTGSGVDAR TASSGSSVWE GQLQSLVLSE YASTEMSLHA LYMHQLHKQQ 730 740 750 760 770 780 TQAEPERHVW HRRESDESGE SAPEEGGEGA RAPQPIPRSA SYPCATPRPG APETTALHGG 790 800 810 820 830 FQRRYGGITD PGTVPRAPSH FSRLPLGGWA EDGQPASRHP EPVPEEGSED ELPPQVHKV

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Heart.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BC089204 mRNA. Translation: AAH89204.1.
IPI	IPI00366973.
RefSeq	NP_001014240.1.
UniGene	Rn.35248
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSRNOG00000018975. Rattus norvegicus. [Contig view]
GeneID	363254.
KEGG	rno:363254.
Organism-specific databases
RGD	1310450. Atg9a.
Phylogenomic databases
HOVERGEN	Q5FWU3.
Gene expression databases
ArrayExpress	Q5FWU3.
GermOnline	ENSRNOG00000018975. Rattus norvegicus.
Family and domain databases
InterPro	IPR007241. Autophagy-rel_prot_9. [Graphical view]
PANTHER	PTHR13038. APG9. 1 hit.
Pfam	PF04109. APG9. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	683017.

Entry information

Entry name

ATG9A_RAT

Accession

Primary (citable) accession number: Q5FWU3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 12, 2005
Last sequence update:	March 1, 2005
Last modified:	June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)