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Protein
Submitted name:

Adaptor protein complex AP-2, mu1

Gene

Ap2m1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei341Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei343Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei345Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei354Phosphatidylinositol lipid headgroupUniRule annotation1
Binding sitei356Phosphatidylinositol lipid headgroupUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transportSAAS annotation, Transport
LigandLipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adaptor protein complex AP-2, mu1Imported
Gene namesi
Name:Ap2m1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1298405 Ap2m1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiQ5FWI9
PRIDEiQ5FWI9

PTM databases

SwissPalmiQ5FWI9

Expressioni

Gene expression databases

BgeeiENSMUSG00000022841
ExpressionAtlasiQ5FWI9 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ5FWI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini170 – 434MHDInterPro annotationAdd BLAST265

Sequence similaritiesi

Belongs to the adaptor complexes medium subunit family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0937 Eukaryota
ENOG410XPFS LUCA
HOVERGENiHBG050516
KOiK11826
OMAiSWRKADV
OrthoDBiEOG091G06XI

Family and domain databases

InterProiView protein in InterPro
IPR036168 AP2_Mu_C_sf
IPR022775 AP_mu_sigma_su
IPR001392 Clathrin_mu
IPR018240 Clathrin_mu_CS
IPR011012 Longin-like_dom_sf
IPR028565 MHD
PfamiView protein in Pfam
PF00928 Adap_comp_sub, 1 hit
PF01217 Clat_adaptor_s, 1 hit
PIRSFiPIRSF005992 Clathrin_mu, 1 hit
PRINTSiPR00314 CLATHRINADPT
SUPFAMiSSF49447 SSF49447, 1 hit
SSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS00990 CLAT_ADAPTOR_M_1, 1 hit
PS00991 CLAT_ADAPTOR_M_2, 1 hit
PS51072 MHD, 1 hit

Sequencei

Sequence statusi: Complete.

Q5FWI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGGLFIYNH KGEVLISRVY RDDIGRNAVD AFRVNVIHAR QQVRSPVTNI
60 70 80 90 100
ARTSFFHVKR SNIWLAAVTK QNVNAAMVFE FLYKMCDVMA AYFGKISEEN
110 120 130 140 150
IKNNFVLIYE LLDEILDFGY PQNSETGALK TFITQQGIKS QHQTKEEQSQ
160 170 180 190 200
ITSQVTGQIG WRREGIKYRR NELFLDVLES VNLLMSPQGQ VLSAHVSGRV
210 220 230 240 250
VMKSYLSGMP ECKFGMNDKI VIEKQGKGTA DETSKSGKQS IAIDDCTFHQ
260 270 280 290 300
CVRLSKFDSE RSISFIPPDG EFELMRYRTT KDIILPFRVI PLVREVGRTK
310 320 330 340 350
LEVKVVIKSN FKPSLLAQKI EVRIPTPLNT SGVQVICMKG KAKYKASENA
360 370 380 390 400
IVWKIKRMAG MKESQISAEI ELLPTNDKKK WARPPISMNF EVPFAPSGLK
410 420 430
VRYLKVFEPK LNYSDHDVIK WVRYIGRSGI YETRC
Length:435
Mass (Da):49,655
Last modified:May 10, 2005 - v1
Checksum:i82803219BA279954
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089342 mRNA Translation: AAH89342.1
BC094510 mRNA Translation: AAH94510.1
AK141862 mRNA Translation: BAE24863.1
AK146517 mRNA Translation: BAE27229.1
RefSeqiNP_001289899.1, NM_001302970.1
NP_033809.1, NM_009679.3
UniGeneiMm.18946

Genome annotation databases

GeneIDi11773
KEGGimmu:11773

Similar proteinsi

Entry informationi

Entry nameiQ5FWI9_MOUSE
AccessioniPrimary (citable) accession number: Q5FWI9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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