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Protein

F-box only protein 48

Gene

FBXO48

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
F-box only protein 48
Gene namesi
Name:FBXO48
Synonyms:FBX48
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000204923.3
HGNCiHGNC:33857 FBXO48
neXtProtiNX_Q5FWF7

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204923
PharmGKBiPA162388158

Polymorphism and mutation databases

BioMutaiFBXO48
DMDMi74755340

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003356771 – 155F-box only protein 48Add BLAST155

Proteomic databases

MaxQBiQ5FWF7
PaxDbiQ5FWF7
PeptideAtlasiQ5FWF7
PRIDEiQ5FWF7

PTM databases

iPTMnetiQ5FWF7
PhosphoSitePlusiQ5FWF7

Expressioni

Gene expression databases

BgeeiENSG00000204923
CleanExiHS_FBXO48

Organism-specific databases

HPAiHPA049775
HPA054782

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
SKP1P632086EBI-11961122,EBI-307486

Protein-protein interaction databases

IntActiQ5FWF7, 1 interactor
STRINGi9606.ENSP00000367193

Structurei

3D structure databases

ProteinModelPortaliQ5FWF7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 79F-boxPROSITE-ProRule annotationAdd BLAST48

Phylogenomic databases

eggNOGiENOG410IX69 Eukaryota
ENOG41125II LUCA
GeneTreeiENSGT00390000012248
HOGENOMiHOG000007150
HOVERGENiHBG094843
InParanoidiQ5FWF7
OMAiLPEKIMY
OrthoDBiEOG091G1A1M
PhylomeDBiQ5FWF7
TreeFamiTF332573

Family and domain databases

InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SUPFAMiSSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit

Sequencei

Sequence statusi: Complete.

Q5FWF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHKNSKRNNN LRVSHTEANS VDAEKEKNES QNNFFELLPA EITFKIFSQL
60 70 80 90 100
DIRSLCRASL TCRSWNDTIR NSDSLWKPHC MTVRAVCRRE IDDDLESGYS
110 120 130 140 150
WRVILLRNYQ KSKVKHEWLS GRYSNICSPI SLPEKIMYPM DADTWGEILE

AELER
Length:155
Mass (Da):18,241
Last modified:March 1, 2005 - v1
Checksum:i135851156496E816
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_04346616T → I. Corresponds to variant dbSNP:rs12614904Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ904332 mRNA Translation: ABI98402.1
BC089423 mRNA Translation: AAH89423.1
CCDSiCCDS33213.1
RefSeqiNP_001019851.1, NM_001024680.2
XP_005264464.1, XM_005264407.2
XP_016859926.1, XM_017004437.1
UniGeneiHs.164117

Genome annotation databases

EnsembliENST00000377957; ENSP00000367193; ENSG00000204923
GeneIDi554251
KEGGihsa:554251
UCSCiuc002seo.5 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiFBX48_HUMAN
AccessioniPrimary (citable) accession number: Q5FWF7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 1, 2005
Last modified: March 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

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