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Q5FW78

- Q5FW78_MOUSE

UniProt

Q5FW78 - Q5FW78_MOUSE

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Protein
Submitted name:

Il7r protein

Gene

Il7r

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cytokine receptor activity Source: InterPro

GO - Biological processi

  1. B cell proliferation Source: MGI
  2. cell growth Source: MGI
  3. cell morphogenesis Source: MGI
  4. homeostasis of number of cells Source: MGI
  5. immunoglobulin production Source: MGI
  6. lymph node development Source: MGI
  7. negative regulation of T cell mediated cytotoxicity Source: MGI
  8. positive regulation of gene expression Source: MGI
  9. positive regulation of T cell differentiation in thymus Source: MGI
  10. regulation of cell size Source: MGI
  11. T cell differentiation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Il7r proteinImported
Gene namesi
Name:Il7rImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96562. Il7r.

Subcellular locationi

GO - Cellular componenti

  1. external side of plasma membrane Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ5FW78.

Structurei

3D structure databases

ProteinModelPortaliQ5FW78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG055773.
KOiK05072.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR003961. Fibronectin_type3.
IPR003531. Hempt_rcpt_S_F1_CS.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF00041. fn3. 1 hit.
[Graphical view]
SMARTiSM00060. FN3. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 1 hit.
PROSITEiPS01355. HEMATOPO_REC_S_F1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FW78 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMALGRAFAI VFCLIQAVSG ESGNAQDGDL EDADADDHSF WCHSQLEVDG
60 70 80 90 100
SQHLLTCAFN DSDINTANLE FQICGALLRV KCLTLNKLQD IYFIKTSEFL
110 120 130 140 150
LIGSSNICVK LGQKNLTCKN MAINTIVKAE APSDLKVVYR KEANDFLVTF
160 170 180 190 200
NAPHLKKKYL KKVKHDVAYR PARGESNWTH VSLFHTRTTI PQRKLRPKAM
210 220 230 240 250
YEIKVRSIPH NDYFKGFWSE WSPSSTFETP EPKNQGGWDP VLPSVTILSL
260 270 280
FSAFLLVILA HVLWKKRIKP VVWPSLPDHK KTLEQL
Length:286
Mass (Da):32,417
Last modified:March 1, 2005 - v1
Checksum:iA96E8356467974A3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC089571 mRNA. Translation: AAH89571.1.
RefSeqiNP_032398.3. NM_008372.4.
UniGeneiMm.389.

Genome annotation databases

GeneIDi16197.
KEGGimmu:16197.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC089571 mRNA. Translation: AAH89571.1 .
RefSeqi NP_032398.3. NM_008372.4.
UniGenei Mm.389.

3D structure databases

ProteinModelPortali Q5FW78.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 16197.
KEGGi mmu:16197.

Organism-specific databases

CTDi 3575.
MGIi MGI:96562. Il7r.

Phylogenomic databases

HOVERGENi HBG055773.
KOi K05072.

Miscellaneous databases

ChiTaRSi IL7R. mouse.
NextBioi 289125.
SOURCEi Search...

Gene expression databases

Genevestigatori Q5FW78.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR003961. Fibronectin_type3.
IPR003531. Hempt_rcpt_S_F1_CS.
IPR013783. Ig-like_fold.
[Graphical view ]
Pfami PF00041. fn3. 1 hit.
[Graphical view ]
SMARTi SM00060. FN3. 1 hit.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 1 hit.
PROSITEi PS01355. HEMATOPO_REC_S_F1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: HeartImported.

Entry informationi

Entry nameiQ5FW78_MOUSE
AccessioniPrimary (citable) accession number: Q5FW78
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)