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Q5FW78

- Q5FW78_MOUSE

UniProt

Q5FW78 - Q5FW78_MOUSE

Protein
Submitted name:

Il7r protein

Gene

Il7r

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (01 Mar 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cytokine receptor activity Source: InterPro

    GO - Biological processi

    1. B cell proliferation Source: MGI
    2. cell growth Source: MGI
    3. cell morphogenesis Source: MGI
    4. homeostasis of number of cells Source: MGI
    5. immunoglobulin production Source: MGI
    6. lymph node development Source: MGI
    7. negative regulation of T cell mediated cytotoxicity Source: MGI
    8. positive regulation of gene expression Source: MGI
    9. positive regulation of T cell differentiation in thymus Source: MGI
    10. regulation of cell size Source: MGI
    11. T cell differentiation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Il7r proteinImported
    Gene namesi
    Name:Il7rImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:96562. Il7r.

    Subcellular locationi

    GO - Cellular componenti

    1. external side of plasma membrane Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ5FW78.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5FW78.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG055773.
    InParanoidiQ5FW78.
    KOiK05072.

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR003961. Fibronectin_type3.
    IPR003531. Hempt_rcpt_S_F1_CS.
    IPR013783. Ig-like_fold.
    [Graphical view]
    PfamiPF00041. fn3. 1 hit.
    [Graphical view]
    SMARTiSM00060. FN3. 1 hit.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 1 hit.
    PROSITEiPS01355. HEMATOPO_REC_S_F1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5FW78-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMALGRAFAI VFCLIQAVSG ESGNAQDGDL EDADADDHSF WCHSQLEVDG    50
    SQHLLTCAFN DSDINTANLE FQICGALLRV KCLTLNKLQD IYFIKTSEFL 100
    LIGSSNICVK LGQKNLTCKN MAINTIVKAE APSDLKVVYR KEANDFLVTF 150
    NAPHLKKKYL KKVKHDVAYR PARGESNWTH VSLFHTRTTI PQRKLRPKAM 200
    YEIKVRSIPH NDYFKGFWSE WSPSSTFETP EPKNQGGWDP VLPSVTILSL 250
    FSAFLLVILA HVLWKKRIKP VVWPSLPDHK KTLEQL 286
    Length:286
    Mass (Da):32,417
    Last modified:March 1, 2005 - v1
    Checksum:iA96E8356467974A3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC089571 mRNA. Translation: AAH89571.1.
    RefSeqiNP_032398.3. NM_008372.4.
    UniGeneiMm.389.

    Genome annotation databases

    GeneIDi16197.
    KEGGimmu:16197.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC089571 mRNA. Translation: AAH89571.1 .
    RefSeqi NP_032398.3. NM_008372.4.
    UniGenei Mm.389.

    3D structure databases

    ProteinModelPortali Q5FW78.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 16197.
    KEGGi mmu:16197.

    Organism-specific databases

    CTDi 3575.
    MGIi MGI:96562. Il7r.

    Phylogenomic databases

    HOVERGENi HBG055773.
    InParanoidi Q5FW78.
    KOi K05072.

    Miscellaneous databases

    ChiTaRSi IL7R. mouse.
    NextBioi 289125.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q5FW78.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR003961. Fibronectin_type3.
    IPR003531. Hempt_rcpt_S_F1_CS.
    IPR013783. Ig-like_fold.
    [Graphical view ]
    Pfami PF00041. fn3. 1 hit.
    [Graphical view ]
    SMARTi SM00060. FN3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 1 hit.
    PROSITEi PS01355. HEMATOPO_REC_S_F1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: HeartImported.

    Entry informationi

    Entry nameiQ5FW78_MOUSE
    AccessioniPrimary (citable) accession number: Q5FW78
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2005
    Last sequence update: March 1, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)