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Protein
Submitted name:

Heparin-binding EGF-like growth factor

Gene

Hbegf

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Heparin-binding EGF-like growth factorImported
Gene namesi
Name:HbegfImported
ORF Names:mCG_121963Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96070. Hbegf.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei162 – 18423HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 208185Sequence analysisPRO_5007924821Add
BLAST

Expressioni

Gene expression databases

BgeeiENSMUSG00000024486.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025363.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini104 – 14441EGF-likeInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IMHM. Eukaryota.
ENOG41120D3. LUCA.
GeneTreeiENSGT00530000063708.
HOVERGENiHBG053952.
KOiK08523.
OMAiYSYDHTT.
OrthoDBiEOG091G0RK4.

Family and domain databases

InterProiIPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR015497. EGF_rcpt_ligand.
[Graphical view]
PANTHERiPTHR10740. PTHR10740. 1 hit.
PfamiPF00008. EGF. 1 hit.
[Graphical view]
PROSITEiPS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FW64-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLPSVMLK LFLAAVLSAL VTGESLERLR RGLAAATSNP DPPTGSTNQL
60 70 80 90 100
LPTGGDRAQG VQDLEGTDLN LFKVAFSSKP QGLATPSKER NGKKKKKGKG
110 120 130 140 150
LGKKRDPCLR KYKDYCIHGE CRYLQEFRTP SCKCLPGYHG HRCHGLTLPV
160 170 180 190 200
ENPLYTYDHT TVLAVVAVVL SSVCLLVIVG LLMFRYHRRG GYDLESEEKV

KLGVASSH
Length:208
Mass (Da):22,808
Last modified:May 10, 2005 - v1
Checksum:i7086934E23D25F8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089607 mRNA. Translation: AAH89607.1.
AK145548 mRNA. Translation: BAE26501.1.
AK160575 mRNA. Translation: BAE35883.1.
AK164309 mRNA. Translation: BAE37729.1.
CH466557 Genomic DNA. Translation: EDK97159.1.
RefSeqiNP_034545.1. NM_010415.2.
UniGeneiMm.289681.

Genome annotation databases

GeneIDi15200.
KEGGimmu:15200.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089607 mRNA. Translation: AAH89607.1.
AK145548 mRNA. Translation: BAE26501.1.
AK160575 mRNA. Translation: BAE35883.1.
AK164309 mRNA. Translation: BAE37729.1.
CH466557 Genomic DNA. Translation: EDK97159.1.
RefSeqiNP_034545.1. NM_010415.2.
UniGeneiMm.289681.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000025363.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi15200.
KEGGimmu:15200.

Organism-specific databases

CTDi1839.
MGIiMGI:96070. Hbegf.

Phylogenomic databases

eggNOGiENOG410IMHM. Eukaryota.
ENOG41120D3. LUCA.
GeneTreeiENSGT00530000063708.
HOVERGENiHBG053952.
KOiK08523.
OMAiYSYDHTT.
OrthoDBiEOG091G0RK4.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024486.

Family and domain databases

InterProiIPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR015497. EGF_rcpt_ligand.
[Graphical view]
PANTHERiPTHR10740. PTHR10740. 1 hit.
PfamiPF00008. EGF. 1 hit.
[Graphical view]
PROSITEiPS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5FW64_MOUSE
AccessioniPrimary (citable) accession number: Q5FW64
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.