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Protein
Submitted name:

Thromboxane A2 receptor

Gene

Tbxa2r

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Thromboxane A2 receptorImported
Gene namesi
Name:Tbxa2rImported
Synonyms:tpImported
ORF Names:mCG_12133Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98496. Tbxa2r.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 50HelicalSequence analysisAdd BLAST22
Transmembranei62 – 85HelicalSequence analysisAdd BLAST24
Transmembranei105 – 126HelicalSequence analysisAdd BLAST22
Transmembranei147 – 172HelicalSequence analysisAdd BLAST26
Transmembranei192 – 221HelicalSequence analysisAdd BLAST30
Transmembranei242 – 267HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000034881.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100962.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 305G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST265

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG108543.
KOiK04264.
OMAiLCHFMGV.
OrthoDBiEOG091G0DNT.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR008365. Prostanoid_rcpt.
IPR001105. Thbox_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01788. PROSTANOIDR.
PR00429. THROMBOXANER.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FW61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWPNGTSLGA CFRPVNITLQ ERRAIASPWF AASFCALGLG SNLLALSVLA
60 70 80 90 100
GARPGAGPRS SFLALLCGLV LTDFLGLLVT GAIVASQHAA LLDWRATDPS
110 120 130 140 150
CRLCYFMGVA MVFFGLCPLL LGAAMASERF VGITRPFSRP TATSRRAWAT
160 170 180 190 200
VGLVWVAAGA LGLLPLLGLG RYSVQYPGSW CFLTLGTQRG DVVFGLIFAL
210 220 230 240 250
LGSASVGLSL LLNTVSVATL CRVYHTREAT QRPRDCEVEM MVQLVGIMVV
260 270 280 290 300
ATVCWMPLLV FIMQTLLQTP PVMSFSGQLL RATEHQLLIY LRVATWNQIL
310 320 330 340
DPWVYILFRR SVLRRLHPRF SSQLQAVSLR RPPAQAMLSG P
Length:341
Mass (Da):37,098
Last modified:May 10, 2005 - v1
Checksum:iF090F027E7D1F234
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089611 mRNA. Translation: AAH89611.1.
BC138885 mRNA. Translation: AAI38886.1.
BC138886 mRNA. Translation: AAI38887.1.
AK158477 mRNA. Translation: BAE34532.1.
AB115920 mRNA. Translation: BAF82013.1.
CH466553 Genomic DNA. Translation: EDL31427.1.
RefSeqiNP_001264194.1. NM_001277265.1.
NP_033351.1. NM_009325.4.
XP_006513523.1. XM_006513460.3.
UniGeneiMm.4545.

Genome annotation databases

GeneIDi21390.
KEGGimmu:21390.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089611 mRNA. Translation: AAH89611.1.
BC138885 mRNA. Translation: AAI38886.1.
BC138886 mRNA. Translation: AAI38887.1.
AK158477 mRNA. Translation: BAE34532.1.
AB115920 mRNA. Translation: BAF82013.1.
CH466553 Genomic DNA. Translation: EDL31427.1.
RefSeqiNP_001264194.1. NM_001277265.1.
NP_033351.1. NM_009325.4.
XP_006513523.1. XM_006513460.3.
UniGeneiMm.4545.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000100962.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi21390.
KEGGimmu:21390.

Organism-specific databases

CTDi6915.
MGIiMGI:98496. Tbxa2r.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG108543.
KOiK04264.
OMAiLCHFMGV.
OrthoDBiEOG091G0DNT.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034881.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR008365. Prostanoid_rcpt.
IPR001105. Thbox_rcpt.
[Graphical view]
PANTHERiPTHR11866. PTHR11866. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01788. PROSTANOIDR.
PR00429. THROMBOXANER.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5FW61_MOUSE
AccessioniPrimary (citable) accession number: Q5FW61
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 30, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.