Q5FW59 (Q5FW59_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Natriuretic peptide type A EMBL AAH89615.1

Submitted name:
Natriuretic peptide type A, isoform CRA_b EMBL EDL14792.1
Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000099520

Gene names

Name:	Nppa MGI 97367 EMBL EDL14792.1 Ensembl ENSMUSP00000099520
ORF Names:	mCG_11724 EMBL EDL14792.1, RP23-128E8.2-001 EMBL CAM14483.1

Organism

Mus musculus (Mouse) EMBL AAH89615.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Secreted By similarity RuleBase RU003686.
Sequence similarities	Belongs to the natriuretic peptide family. RuleBase RU003686

Ontologies

Keywords
Molecular function	Vasoactive SAAS SAAS000663 RuleBase RU003686
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of blood vessel size Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5FW59 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: 1693D134B5FCA23D	FASTA	152	16,572
	10 20 30 40 50 60 MGSFSITLGF FLVLAFWLPG HIGANPVYSA VSNTDLMDFK NLLDHLEEKM PVEDEVMPPQ 70 80 90 100 110 120 ALSEQTEEAG AALSSLPEVP PWTGEVNPPL RDGSALGRSP WDPSDRSALL KSKLRALLAG 130 140 150 PRSLRRSSCF GGRIDRIGAQ SGLGCNSFRY RR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed: 16141073] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[2]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed: 11076861] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[3]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed: 12040188] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL14792.1.
[4]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000099520.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[6]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed: 10349636] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[7]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed: 11042159] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[8]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[9]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[10]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Heart EMBL AAH89615.1.
[11]	Howden P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[12]	Garner P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[13]	Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y. Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAE27742.1. Tissue: Heart EMBL BAE27742.1.
[14]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000099520.
[15]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL14792.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC089615 mRNA. Translation: AAH89615.1. AK147180 mRNA. Translation: BAE27742.1. AL714013 Genomic DNA. Translation: CAM14483.1. CU210867 Genomic DNA. Translation: CAQ52160.1. CH466594 Genomic DNA. Translation: EDL14792.1.
IPI	IPI00553811.
RefSeq	NP_032751.1. NM_008725.2.
UniGene	Mm.482123.
3D structure databases
ProteinModelPortal	Q5FW59.
SMR	Q5FW59. Positions 121-149.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5FW59.
Proteomic databases
PRIDE	Q5FW59.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000103230; ENSMUSP00000099520; ENSMUSG00000041616.
GeneID	230899.
KEGG	mmu:230899.
UCSC	uc008vtq.1. mouse.
Organism-specific databases
CTD	4878.
MGI	MGI:97367. Nppa.
Phylogenomic databases
GeneTree	ENSGT00510000048659.
HOVERGEN	HBG004227.
InParanoid	Q5FW59.
OMA	EVPPWTG.
PhylomeDB	Q5FW59.
Gene expression databases
ArrayExpress	Q5FW59.
Bgee	Q5FW59.
Genevestigator	Q5FW59.
Family and domain databases
InterPro	IPR000663. Natr_peptide. IPR002407. Natriuretic_peptide_atrial. [Graphical view]
KO	K12334.
Pfam	PF00212. ANP. 1 hit. [Graphical view]
PRINTS	PR00711. ANATPEPTIDE. PR00710. NATPEPTIDES.
SMART	SM00183. NAT_PEP. 1 hit. [Graphical view]
PROSITE	PS00263. NATRIURETIC_PEPTIDE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	380268.
SOURCE	Search...

Entry information

Entry name

Q5FW59_MOUSE

Accession

Primary (citable) accession number: Q5FW59

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2005
Last sequence update:	March 1, 2005
Last modified:	November 16, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)