Q5FVM7 (DJC16_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DnaJ homolog subfamily C member 16

Gene names

Name:

Dnajc16

Organism

Rattus norvegicus (Rat)

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	771 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Single-pass type IV membrane protein Potential.
Sequence similarities	Contains 1 J domain. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Membrane
Domain	Signal Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro protein folding Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	heat shock protein binding Inferred from electronic annotation. Source: InterPro unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 771	746	DnaJ homolog subfamily C member 16		PRO_0000236686
Regions
	Topological domain	26 – 532	507	Cytoplasmic Potential
	Transmembrane	533 – 553	21	Helical; Anchor for type IV membrane protein; Potential
	Topological domain	554 – 771	218	Extracellular Potential
	Domain	29 – 93	65	J
	Domain	116 – 244	129	Thioredoxin
Amino acid modifications
	Glycosylation	628	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5FVM7 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: F9B65C08A01D4C63	FASTA	771	88,870
	10 20 30 40 50 60 MELKRLSISW QFLIVLVLIL QSLSALDFDP YRVLGVSRTA SQADIKKAYK KLAREWHPDK 70 80 90 100 110 120 NKDPGAEDKF IQISKAYEIL SNEEKRTNYD HYGDAGENQG YQQQREYRFR HFHENFYFDE 130 140 150 160 170 180 SFFHFPFNSE RRDSIDEKYL LHFSHYVNEV VPDSFKKPYL IKITSDWCFS CIHIEPIWKE 190 200 210 220 230 240 VVQELEGLGV GIGVVHAGYE RRLAHHLGAH STPSILGIIN GKISFFHNAV VHENLRQFVE 250 260 270 280 290 300 SLLPGNLVEK VTNKNYVRFL SGWQQENKPH ALLFGQTPAA PLLYKLTAFA YKDYVSFGYV 310 320 330 340 350 360 YVGLRGVEEM TRQYNVNIYA PTMLIFKEHI NKPADAIQAR GLKKQVIEDF ITQNKYLLAS 370 380 390 400 410 420 RLTSQKLFHE LCPVKRSHRQ RKYCVVLLTA EANKLSKPFD AFLSFALANT QDTVRFVHVY 430 440 450 460 470 480 SSRQQEFAST LLPDIEAFQG KSGVSILERR NTAGRVVFKT LEDPWTGSES DKFVLLGYLD 490 500 510 520 530 540 QLRKDPAFLS SEAVLPDLTD ELAPVFLLRW LYSVSDYLSD FWESLLHSNW REMMPLLSLI 550 560 570 580 590 600 FSALFILFGT VIVQAFSDSN EERESHPPDK EEVPEKAGKT EPSFTKESSS KIPKKGFVEV 610 620 630 640 650 660 TELTDVTYTS NLVRLRPGHM NVVLILSNST KTSLLQKFAL EVYTFTGSSS LHFSFLTLDK 670 680 690 700 710 720 HREWLEYLLE FAQDAAPIPN QYDKHFMERD YTGYVLALNG HKKYFCLFKP LKTVDEETVG 730 740 750 760 770 SCDLDSSRGK PPCGLGPKPL KGKLSKLSLW MERLLEGSLQ RFYIPSWPEL D

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Liver.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC089875 mRNA. Translation: AAH89875.1.
IPI	IPI00359144.
RefSeq	NP_001014216.1. NM_001014194.1.
UniGene	Rn.198307.
3D structure databases
ProteinModelPortal	Q5FVM7.
SMR	Q5FVM7. Positions 19-100.
ModBase	Search...
Proteomic databases
PRIDE	Q5FVM7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000017247; ENSRNOP00000017247; ENSRNOG00000012503.
GeneID	362652.
KEGG	rno:362652.
NMPDR	fig|10116.3.peg.24291.
UCSC	NM_001014194. rat.
Organism-specific databases
CTD	23341.
RGD	1359395. Dnajc16.
Phylogenomic databases
eggNOG	roNOG10127.
GeneTree	ENSGT00550000074587.
HOVERGEN	HBG055742.
InParanoid	Q5FVM7.
OMA	KLTAFAY.
OrthoDB	EOG4SQWW3.
Gene expression databases
Genevestigator	Q5FVM7.
GermOnline	ENSRNOG00000012503. Rattus norvegicus.
Family and domain databases
InterPro	IPR001623. DnaJ_N. IPR018253. Heat_shock_DnaJ_CS. IPR003095. Hsp_DnaJ. IPR012336. Thioredoxin-like_fold. IPR013766. Thioredoxin_domain. [Graphical view]
Gene3D	G3DSA:1.10.287.110. DnaJ_N. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
KO	K09536.
Pfam	PF00226. DnaJ. 1 hit. PF00085. Thioredoxin. 1 hit. [Graphical view]
PRINTS	PR00625. JDOMAIN.
SMART	SM00271. DnaJ. 1 hit. [Graphical view]
SUPFAM	SSF46565. DnaJ_N. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS00636. DNAJ_1. 1 hit. PS50076. DNAJ_2. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	680755.

Entry information

Entry name

DJC16_RAT

Accession

Primary (citable) accession number: Q5FVM7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	March 1, 2005
Last modified:	November 16, 2011
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program