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Reviewed, UniProtKB/Swiss-Prot Q5FVM7 (DJC16_RAT)

Last modified May 5, 2009. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    DnaJ homolog subfamily C member 16
Gene names
Name: Dnajc16
OrganismRattus norvegicus (Rat)
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length771 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Subcellular location

Membrane; Single-pass type IV membrane protein Potential.

Sequence similarities

Contains 1 J domain.

Contains 1 thioredoxin domain.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
   PTMGlycoprotein
Gene Ontology (GO)
   Biological processcell redox homeostasis

Inferred from electronic annotation. Source: InterPro

protein folding

Inferred from electronic annotation. Source: InterPro

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionheat shock protein binding

Inferred from electronic annotation. Source: InterPro

unfolded protein binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 771746DnaJ homolog subfamily C member 16
PRO_0000236686

Regions

Topological domain26 – 532507Cytoplasmic Potential
Transmembrane533 – 55321Anchor for type IV membrane protein Potential
Topological domain554 – 771218Extracellular Potential
Domain29 – 9365J
Domain116 – 244129Thioredoxin

Amino acid modifications

Glycosylation6281N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q5FVM7-1 [UniParc].

Last modified March 1, 2005. Version 1.
Checksum: F9B65C08A01D4C63

FASTA77188,870
        10         20         30         40         50         60 
MELKRLSISW QFLIVLVLIL QSLSALDFDP YRVLGVSRTA SQADIKKAYK KLAREWHPDK 

        70         80         90        100        110        120 
NKDPGAEDKF IQISKAYEIL SNEEKRTNYD HYGDAGENQG YQQQREYRFR HFHENFYFDE 

       130        140        150        160        170        180 
SFFHFPFNSE RRDSIDEKYL LHFSHYVNEV VPDSFKKPYL IKITSDWCFS CIHIEPIWKE 

       190        200        210        220        230        240 
VVQELEGLGV GIGVVHAGYE RRLAHHLGAH STPSILGIIN GKISFFHNAV VHENLRQFVE 

       250        260        270        280        290        300 
SLLPGNLVEK VTNKNYVRFL SGWQQENKPH ALLFGQTPAA PLLYKLTAFA YKDYVSFGYV 

       310        320        330        340        350        360 
YVGLRGVEEM TRQYNVNIYA PTMLIFKEHI NKPADAIQAR GLKKQVIEDF ITQNKYLLAS 

       370        380        390        400        410        420 
RLTSQKLFHE LCPVKRSHRQ RKYCVVLLTA EANKLSKPFD AFLSFALANT QDTVRFVHVY 

       430        440        450        460        470        480 
SSRQQEFAST LLPDIEAFQG KSGVSILERR NTAGRVVFKT LEDPWTGSES DKFVLLGYLD 

       490        500        510        520        530        540 
QLRKDPAFLS SEAVLPDLTD ELAPVFLLRW LYSVSDYLSD FWESLLHSNW REMMPLLSLI 

       550        560        570        580        590        600 
FSALFILFGT VIVQAFSDSN EERESHPPDK EEVPEKAGKT EPSFTKESSS KIPKKGFVEV 

       610        620        630        640        650        660 
TELTDVTYTS NLVRLRPGHM NVVLILSNST KTSLLQKFAL EVYTFTGSSS LHFSFLTLDK 

       670        680        690        700        710        720 
HREWLEYLLE FAQDAAPIPN QYDKHFMERD YTGYVLALNG HKKYFCLFKP LKTVDEETVG 

       730        740        750        760        770 
SCDLDSSRGK PPCGLGPKPL KGKLSKLSLW MERLLEGSLQ RFYIPSWPEL D 

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References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Liver.

Cross-references

Sequence databases

BC089875 mRNA. Translation: AAH89875.1.
IPIIPI00359144.
RefSeqNP_001014216.1.
UniGeneRn.198307

3D structure databases

SMRQ5FVM7. Positions 19-99.
ModBaseSearch...

Genome annotation databases

EnsemblENSRNOG00000012503. Rattus norvegicus. [Contig view]
GeneID362652.
KEGGrno:362652.
NMPDRfig|10116.3.peg.24291.

Organism-specific databases

RGD1359395. Dnajc16.

Phylogenomic databases

HOVERGENQ5FVM7.
OMAQ5FVM7. KLTAFAY.

Gene expression databases

ArrayExpressQ5FVM7.
GermOnlineENSRNOG00000012503. Rattus norvegicus.

Family and domain databases

InterProIPR001623. DnaJ_N.
IPR018253. Heat_shock_DnaJ_CS.
IPR015609. Hsp40/DnaJ_Rel.
IPR003095. Hsp_DnaJ.
IPR017936. Thioredoxin-like.
IPR012335. Thioredoxin_fold.
[Graphical view]
Gene3DG3DSA:1.10.287.110. DnaJ_N. 1 hit.
G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PANTHERPTHR11821. Hsp40/DnaJ_Rel. 1 hit.
PfamPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSPR00625. DNAJPROTEIN.
SMARTSM00271. DnaJ. 1 hit.
[Graphical view]
PROSITEPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio680755.

Entry information

Entry nameDJC16_RAT
AccessionPrimary (citable) accession number: Q5FVM7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: March 1, 2005
Last modified: May 5, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents