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Protein

Complement C1q tumor necrosis factor-related protein 5

Gene

C1qtnf5

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Complement C1q tumor necrosis factor-related protein 5
Gene namesi
Name:C1qtnf5
Synonyms:Ctrp5
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1308802. C1qtnf5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1515By similarityAdd
BLAST
Chaini16 – 243228Complement C1q tumor necrosis factor-related protein 5PRO_0000003537Add
BLAST

Proteomic databases

PaxDbiQ5FVH0.
PRIDEiQ5FVH0.

Expressioni

Gene expression databases

GenevisibleiQ5FVH0. RN.

Interactioni

Subunit structurei

Homotrimer (via collagen-like domain). May form higher order oligomers by supercoiling of the trimers. May interact with FAM132B (By similarity).By similarity

Protein-protein interaction databases

IntActiQ5FVH0. 1 interaction.
MINTiMINT-1794064.
STRINGi10116.ENSRNOP00000010127.

Structurei

3D structure databases

ProteinModelPortaliQ5FVH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 9566Collagen-likeAdd
BLAST
Domaini99 – 238140C1qPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 C1q domain.PROSITE-ProRule annotation
Contains 1 collagen-like domain.Curated

Keywords - Domaini

Collagen, Signal

Phylogenomic databases

eggNOGiENOG410IHSH. Eukaryota.
ENOG410YPYW. LUCA.
GeneTreeiENSGT00760000118830.
HOGENOMiHOG000085653.
HOVERGENiHBG108220.
InParanoidiQ5FVH0.
OMAiINEQGHY.
OrthoDBiEOG70ZZPW.
PhylomeDBiQ5FVH0.
TreeFamiTF329591.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR001073. C1q_dom.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00386. C1q. 1 hit.
PF01391. Collagen. 2 hits.
[Graphical view]
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiSM00110. C1Q. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50871. C1Q. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5FVH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLLALLLL GLASGSPPLD DNKIPSLCPG QPGLPGTPGH HGSQGLPGRD
60 70 80 90 100
GRDGRDGAPG APGEKGEGGR PGLPGPRGEP GPRGEAGPVG AIGPAGECSV
110 120 130 140 150
PPRSAFSAKR SESRVPPPAD TPLPFDRVLL NEQGHYDATT GKFTCQVPGV
160 170 180 190 200
YYFAVHATVY RASLQFDLVK NGQSIASFFQ FFGGWPKPAS LSGGAMVRLE
210 220 230 240
PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP VFA
Length:243
Mass (Da):25,334
Last modified:March 1, 2005 - v1
Checksum:i178AB5F39D52B041
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089992 mRNA. Translation: AAH89992.1.
RefSeqiNP_001012123.1. NM_001012123.1.
UniGeneiRn.99884.

Genome annotation databases

EnsembliENSRNOT00000010127; ENSRNOP00000010127; ENSRNOG00000007613.
GeneIDi315598.
KEGGirno:315598.
UCSCiRGD:1308802. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089992 mRNA. Translation: AAH89992.1.
RefSeqiNP_001012123.1. NM_001012123.1.
UniGeneiRn.99884.

3D structure databases

ProteinModelPortaliQ5FVH0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5FVH0. 1 interaction.
MINTiMINT-1794064.
STRINGi10116.ENSRNOP00000010127.

Proteomic databases

PaxDbiQ5FVH0.
PRIDEiQ5FVH0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000010127; ENSRNOP00000010127; ENSRNOG00000007613.
GeneIDi315598.
KEGGirno:315598.
UCSCiRGD:1308802. rat.

Organism-specific databases

CTDi114902.
RGDi1308802. C1qtnf5.

Phylogenomic databases

eggNOGiENOG410IHSH. Eukaryota.
ENOG410YPYW. LUCA.
GeneTreeiENSGT00760000118830.
HOGENOMiHOG000085653.
HOVERGENiHBG108220.
InParanoidiQ5FVH0.
OMAiINEQGHY.
OrthoDBiEOG70ZZPW.
PhylomeDBiQ5FVH0.
TreeFamiTF329591.

Miscellaneous databases

PROiQ5FVH0.

Gene expression databases

GenevisibleiQ5FVH0. RN.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR001073. C1q_dom.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00386. C1q. 1 hit.
PF01391. Collagen. 2 hits.
[Graphical view]
PRINTSiPR00007. COMPLEMNTC1Q.
SMARTiSM00110. C1Q. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS50871. C1Q. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiC1QT5_RAT
AccessioniPrimary (citable) accession number: Q5FVH0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 1, 2005
Last modified: June 8, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.