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Protein

Complement C1q tumor necrosis factor-related protein 5

Gene

C1qtnf5

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Complement C1q tumor necrosis factor-related protein 5
Gene namesi
Name:C1qtnf5
Synonyms:Ctrp5
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1308802 C1qtnf5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15By similarityAdd BLAST15
ChainiPRO_000000353716 – 243Complement C1q tumor necrosis factor-related protein 5Add BLAST228

Proteomic databases

PaxDbiQ5FVH0
PRIDEiQ5FVH0

PTM databases

PhosphoSitePlusiQ5FVH0

Expressioni

Gene expression databases

BgeeiENSRNOG00000007613
GenevisibleiQ5FVH0 RN

Interactioni

Subunit structurei

Homotrimer (via collagen-like domain). May form higher order oligomers by supercoiling of the trimers. May interact with ERFE (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ5FVH0, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ5FVH0
SMRiQ5FVH0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 95Collagen-likeAdd BLAST66
Domaini99 – 238C1qPROSITE-ProRule annotationAdd BLAST140

Keywords - Domaini

Collagen, Signal

Phylogenomic databases

eggNOGiENOG410IHSH Eukaryota
ENOG410YPYW LUCA
GeneTreeiENSGT00760000118830
HOGENOMiHOG000085653
HOVERGENiHBG108220
InParanoidiQ5FVH0
OMAiSDWKNSA
OrthoDBiEOG091G0L3Y
PhylomeDBiQ5FVH0
TreeFamiTF329591

Family and domain databases

Gene3Di2.60.120.40, 1 hit
InterProiView protein in InterPro
IPR001073 C1q_dom
IPR008160 Collagen
IPR008983 Tumour_necrosis_fac-like_dom
PfamiView protein in Pfam
PF00386 C1q, 1 hit
PF01391 Collagen, 2 hits
PRINTSiPR00007 COMPLEMNTC1Q
SMARTiView protein in SMART
SM00110 C1Q, 1 hit
SUPFAMiSSF49842 SSF49842, 1 hit
PROSITEiView protein in PROSITE
PS50871 C1Q, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5FVH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLLALLLL GLASGSPPLD DNKIPSLCPG QPGLPGTPGH HGSQGLPGRD
60 70 80 90 100
GRDGRDGAPG APGEKGEGGR PGLPGPRGEP GPRGEAGPVG AIGPAGECSV
110 120 130 140 150
PPRSAFSAKR SESRVPPPAD TPLPFDRVLL NEQGHYDATT GKFTCQVPGV
160 170 180 190 200
YYFAVHATVY RASLQFDLVK NGQSIASFFQ FFGGWPKPAS LSGGAMVRLE
210 220 230 240
PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP VFA
Length:243
Mass (Da):25,334
Last modified:March 1, 2005 - v1
Checksum:i178AB5F39D52B041
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC089992 mRNA Translation: AAH89992.1
RefSeqiNP_001012123.1, NM_001012123.1
XP_017451111.1, XM_017595622.1
UniGeneiRn.99884

Genome annotation databases

EnsembliENSRNOT00000010127; ENSRNOP00000010127; ENSRNOG00000007613
GeneIDi315598
KEGGirno:315598
UCSCiRGD:1308802 rat

Similar proteinsi

Entry informationi

Entry nameiC1QT5_RAT
AccessioniPrimary (citable) accession number: Q5FVH0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: March 1, 2005
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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