tsf

Functionⁱ

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.UniRule annotation

GO - Molecular functionⁱ

translation elongation factor activity Source: UniProtKB-KW

Complete GO annotation...

Keywordsⁱ

Molecular function	Elongation factor
Biological process	Protein biosynthesis

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Elongation factor TsUniRule annotation Short name: EF-TsUniRule annotation
Gene namesⁱ	Name:tsfUniRule annotation Ordered Locus Names:GOX0074
Organismⁱ	Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Taxonomic identifierⁱ	290633 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconobacter › Gluconobacter oxydans
Proteomesⁱ	UP000006375 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00050

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000241486	1 – 302	Elongation factor TsAdd BLAST		302

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	290633.GOX0074.

STRINGⁱ

290633.GOX0074.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5FUV8.
SMRⁱ	Q5FUV8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	80 – 83	Involved in Mg(2+) ion dislocation from EF-TuUniRule annotation		4

Sequence similaritiesⁱ

Belongs to the EF-Ts family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105CU7. Bacteria. COG0264. LUCA.
HOGENOMⁱ	HOG000220986.
KEGG Orthology (KO) More...KOⁱ	K02357.
OMAⁱ	DAGMMDC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H02HG.

Family and domain databases

Gene3Dⁱ	3.30.479.20. 2 hits.
HAMAPⁱ	MF_00050. EF_Ts. 1 hit.
InterProⁱ	View protein in InterPro IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like.
PANTHERⁱ	PTHR11741. PTHR11741. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00889. EF_TS. 1 hit.
SUPFAMⁱ	SSF46934. SSF46934. 1 hit. SSF54713. SSF54713. 2 hits.
TIGRFAMsⁱ	TIGR00116. tsf. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01126. EF_TS_1. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5FUV8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAEITAALVR ELREATGAGM MDCKKALTEA AGDMEAAIDW LRTKGLSQAA 
        60         70         80         90        100
KKSGRTTAEG LVGVASAKNR AAMVEVNAET DFVGRNEAFQ AFVEQVAHVA 
       110        120        130        140        150
LEVGDDLDAI KAGKVPSGRT VADELTHLIA TIGENMAIRR AKVLSVESGV 
       160        170        180        190        200
VASYVHSALR PGIGKIGVLA ALEAPSESDA LLTLGRQIGM HVAATRPAAL 
       210        220        230        240        250
DVASVDPEAL ERERAVLIEQ ARESGKPEAI IEKMVEGRIR KFYEEVVLLE 
       260        270        280        290        300
QVWVLDGESR VAKVVEKAGA KLVGFERFQL GEGIEKEESD FAAEVAAAAG 

TK

Length:302

Mass (Da):31,973

Last modified:March 1, 2005 - v1

Checksum:ⁱ5B2E9FE03877E7B2

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000009 Genomic DNA. Translation: AAW59871.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011251675.1. NC_006677.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAW59871; AAW59871; GOX0074.
GeneIDⁱ	29627620.
KEGGⁱ	gox:GOX0074.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000009 Genomic DNA. Translation: AAW59871.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011251675.1. NC_006677.1.

3D structure databases

ProteinModelPortalⁱ	Q5FUV8.
SMRⁱ	Q5FUV8.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	290633.GOX0074.

STRINGⁱ

290633.GOX0074.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAW59871; AAW59871; GOX0074.
GeneIDⁱ	29627620.
KEGGⁱ	gox:GOX0074.

Phylogenomic databases

eggNOGⁱ	ENOG4105CU7. Bacteria. COG0264. LUCA.
HOGENOMⁱ	HOG000220986.
KEGG Orthology (KO) More...KOⁱ	K02357.
OMAⁱ	DAGMMDC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H02HG.

Family and domain databases

Gene3Dⁱ	3.30.479.20. 2 hits.
HAMAPⁱ	MF_00050. EF_Ts. 1 hit.
InterProⁱ	View protein in InterPro IPR001816. Transl_elong_EFTs/EF1B. IPR014039. Transl_elong_EFTs/EF1B_dimer. IPR018101. Transl_elong_Ts_CS. IPR009060. UBA-like.
PANTHERⁱ	PTHR11741. PTHR11741. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00889. EF_TS. 1 hit.
SUPFAMⁱ	SSF46934. SSF46934. 1 hit. SSF54713. SSF54713. 2 hits.
TIGRFAMsⁱ	TIGR00116. tsf. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01126. EF_TS_1. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	EFTS_GLUOX
Accessionⁱ	Q5FUV8Primary (citable) accession number: Q5FUV8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
	Last sequence update:	March 1, 2005
	Last modified:	June 7, 2017
	This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

UniProtKB - Q5FUV8 (EFTS_GLUOX)

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Elongation factor Ts

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Functionⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Molecule processing

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Region

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5FUV8 (EFTS_GLUOX)

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Elongation factor Ts

tsf

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ