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Protein

Thymidine kinase

Gene

GOX0257

Organism
Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciGOXY290633:GHB3-257-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:GOX0257Imported
OrganismiGluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)Imported
Taxonomic identifieri290633 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconobacter
ProteomesiUP000006375 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi290633.GOX0257.

Structurei

3D structure databases

ProteinModelPortaliQ5FUA6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OrthoDBiEOG69D3J2.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5FUA6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVRGRLVLY VGPMFAGKSA HLIAAAKRQT DVLALKPGFD TRDGSELVSR
60 70 80 90 100
DGSHLAAVSA NAWPEDADRY SHIVLDEGQF WVAPHYHGDI VEDIRAARAR
110 120 130 140 150
GADVTVGGLD TDYRRVPFDV MTRLMDEADE VIALTARCHV CGAPAAWTAK
160 170 180
THETGHLLET GDQELYEARC DAHWTLPDRP
Length:180
Mass (Da):19,791
Last modified:March 1, 2005 - v1
Checksum:iD2EE672D897B1D3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000009 Genomic DNA. Translation: AAW60040.1.
RefSeqiYP_190696.1. NC_006677.1.

Genome annotation databases

EnsemblBacteriaiAAW60040; AAW60040; GOX0257.
KEGGigox:GOX0257.
PATRICi32608194. VBIGluOxy81109_0478.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000009 Genomic DNA. Translation: AAW60040.1.
RefSeqiYP_190696.1. NC_006677.1.

3D structure databases

ProteinModelPortaliQ5FUA6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290633.GOX0257.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW60040; AAW60040; GOX0257.
KEGGigox:GOX0257.
PATRICi32608194. VBIGluOxy81109_0478.

Phylogenomic databases

HOGENOMiHOG000076390.
KOiK00857.
OrthoDBiEOG69D3J2.

Enzyme and pathway databases

BioCyciGOXY290633:GHB3-257-MONOMER.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans."
    Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U.
    Nat. Biotechnol. 23:195-200(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 621HImported.

Entry informationi

Entry nameiQ5FUA6_GLUOX
AccessioniPrimary (citable) accession number: Q5FUA6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2005
Last sequence update: March 1, 2005
Last modified: April 1, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.