Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5FUA3

- LPXB_GLUOX

UniProt

Q5FUA3 - LPXB_GLUOX

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (01 Mar 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

    Catalytic activityi

    UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    BioCyciGOXY290633:GHB3-260-MONOMER.
    UniPathwayiUPA00359; UER00481.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
    Gene namesi
    Name:lpxBUniRule annotation
    Ordered Locus Names:GOX0260
    OrganismiGluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
    Taxonomic identifieri290633 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconobacter
    ProteomesiUP000006375: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 415415Lipid-A-disaccharide synthasePRO_0000255185Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi290633.GOX0260.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5FUA3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LpxB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0763.
    HOGENOMiHOG000018004.
    KOiK00748.
    OMAiVSPITYR.
    OrthoDBiEOG6FBWZR.

    Family and domain databases

    HAMAPiMF_00392. LpxB.
    InterProiIPR003835. Glyco_trans_19.
    [Graphical view]
    PfamiPF02684. LpxB. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00215. lpxB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5FUA3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNSLPESGSD GQSSADPSQK ATSLPRYGRV IWILAGEASG DVIGARLMQA    50
    LHAQDPSLVF AGVGGGRMEA LGLHSLFPMS DLAVMGLVEV VPRLRQLSQR 100
    LLEAVQDIEL RKPDLVVTID SPGFTLRLLQ KIERSGIKRV HYVAPQVWAW 150
    RENRVKEFPG LWDRLLCLLP FEPDWFAQRG LEGRFVGHPV LQSGVRQGNA 200
    QRFRLRHNIP AHAPVVILMP GSRRSEAPRL LPVFRKMLDI LRVQYPDICP 250
    VIPVAPVIAP TIRQLIRKWP IQPHIVTDIH DKHDAFAAAQ CALTKSGTST 300
    LELAMGNVPM AVTYRVNPVT ATIARRLIKV PHVAMVNLLA GREVVPELLQ 350
    ENCTPKKLAE TVSKLLSDPQ MVEKQRMAFA DVLDKLSPPV GTPADAAAAE 400
    IMDLLNEPVS RSSRS 415
    Length:415
    Mass (Da):45,766
    Last modified:March 1, 2005 - v1
    Checksum:i646CD6305F61E91C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000009 Genomic DNA. Translation: AAW60043.1.
    RefSeqiWP_011251846.1. NC_006677.1.
    YP_190699.1. NC_006677.1.

    Genome annotation databases

    EnsemblBacteriaiAAW60043; AAW60043; GOX0260.
    GeneIDi3248638.
    KEGGigox:GOX0260.
    PATRICi32608202. VBIGluOxy81109_0482.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000009 Genomic DNA. Translation: AAW60043.1 .
    RefSeqi WP_011251846.1. NC_006677.1.
    YP_190699.1. NC_006677.1.

    3D structure databases

    ProteinModelPortali Q5FUA3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290633.GOX0260.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAW60043 ; AAW60043 ; GOX0260 .
    GeneIDi 3248638.
    KEGGi gox:GOX0260.
    PATRICi 32608202. VBIGluOxy81109_0482.

    Phylogenomic databases

    eggNOGi COG0763.
    HOGENOMi HOG000018004.
    KOi K00748.
    OMAi VSPITYR.
    OrthoDBi EOG6FBWZR.

    Enzyme and pathway databases

    UniPathwayi UPA00359 ; UER00481 .
    BioCyci GOXY290633:GHB3-260-MONOMER.

    Family and domain databases

    HAMAPi MF_00392. LpxB.
    InterProi IPR003835. Glyco_trans_19.
    [Graphical view ]
    Pfami PF02684. LpxB. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00215. lpxB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans."
      Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U.
      Nat. Biotechnol. 23:195-200(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 621H.

    Entry informationi

    Entry nameiLPXB_GLUOX
    AccessioniPrimary (citable) accession number: Q5FUA3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: March 1, 2005
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3