Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5FUA3

- LPXB_GLUOX

UniProt

Q5FUA3 - LPXB_GLUOX

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Lipid-A-disaccharide synthase

Gene

lpxB

Organism
Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.UniRule annotation

Catalytic activityi

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. lipid-A-disaccharide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism

Enzyme and pathway databases

BioCyciGOXY290633:GHB3-260-MONOMER.
UniPathwayiUPA00359; UER00481.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid-A-disaccharide synthaseUniRule annotation (EC:2.4.1.182UniRule annotation)
Gene namesi
Name:lpxBUniRule annotation
Ordered Locus Names:GOX0260
OrganismiGluconobacter oxydans (strain 621H) (Gluconobacter suboxydans)
Taxonomic identifieri290633 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconobacter
ProteomesiUP000006375: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 415415Lipid-A-disaccharide synthasePRO_0000255185Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290633.GOX0260.

Structurei

3D structure databases

ProteinModelPortaliQ5FUA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LpxB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0763.
HOGENOMiHOG000018004.
KOiK00748.
OMAiVSPITYR.
OrthoDBiEOG6FBWZR.

Family and domain databases

HAMAPiMF_00392. LpxB.
InterProiIPR003835. Glyco_trans_19.
[Graphical view]
PfamiPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00215. lpxB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5FUA3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSLPESGSD GQSSADPSQK ATSLPRYGRV IWILAGEASG DVIGARLMQA
60 70 80 90 100
LHAQDPSLVF AGVGGGRMEA LGLHSLFPMS DLAVMGLVEV VPRLRQLSQR
110 120 130 140 150
LLEAVQDIEL RKPDLVVTID SPGFTLRLLQ KIERSGIKRV HYVAPQVWAW
160 170 180 190 200
RENRVKEFPG LWDRLLCLLP FEPDWFAQRG LEGRFVGHPV LQSGVRQGNA
210 220 230 240 250
QRFRLRHNIP AHAPVVILMP GSRRSEAPRL LPVFRKMLDI LRVQYPDICP
260 270 280 290 300
VIPVAPVIAP TIRQLIRKWP IQPHIVTDIH DKHDAFAAAQ CALTKSGTST
310 320 330 340 350
LELAMGNVPM AVTYRVNPVT ATIARRLIKV PHVAMVNLLA GREVVPELLQ
360 370 380 390 400
ENCTPKKLAE TVSKLLSDPQ MVEKQRMAFA DVLDKLSPPV GTPADAAAAE
410
IMDLLNEPVS RSSRS
Length:415
Mass (Da):45,766
Last modified:March 1, 2005 - v1
Checksum:i646CD6305F61E91C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000009 Genomic DNA. Translation: AAW60043.1.
RefSeqiWP_011251846.1. NC_006677.1.
YP_190699.1. NC_006677.1.

Genome annotation databases

EnsemblBacteriaiAAW60043; AAW60043; GOX0260.
GeneIDi3248638.
KEGGigox:GOX0260.
PATRICi32608202. VBIGluOxy81109_0482.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000009 Genomic DNA. Translation: AAW60043.1 .
RefSeqi WP_011251846.1. NC_006677.1.
YP_190699.1. NC_006677.1.

3D structure databases

ProteinModelPortali Q5FUA3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290633.GOX0260.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAW60043 ; AAW60043 ; GOX0260 .
GeneIDi 3248638.
KEGGi gox:GOX0260.
PATRICi 32608202. VBIGluOxy81109_0482.

Phylogenomic databases

eggNOGi COG0763.
HOGENOMi HOG000018004.
KOi K00748.
OMAi VSPITYR.
OrthoDBi EOG6FBWZR.

Enzyme and pathway databases

UniPathwayi UPA00359 ; UER00481 .
BioCyci GOXY290633:GHB3-260-MONOMER.

Family and domain databases

HAMAPi MF_00392. LpxB.
InterProi IPR003835. Glyco_trans_19.
[Graphical view ]
Pfami PF02684. LpxB. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00215. lpxB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans."
    Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U.
    Nat. Biotechnol. 23:195-200(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 621H.

Entry informationi

Entry nameiLPXB_GLUOX
AccessioniPrimary (citable) accession number: Q5FUA3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 1, 2005
Last modified: October 1, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3