Q5FQ78 (Q5FQ78_GLUOX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Exodeoxyribonuclease 7 large subunit HAMAP-Rule MF_00378
EC=3.1.11.6 HAMAP-Rule MF_00378

Alternative name(s):
Exodeoxyribonuclease VII large subunit HAMAP-Rule MF_00378

Gene names

Name:	xseA HAMAP-Rule MF_00378
Ordered Locus Names:	GOX1729 EMBL AAW61468.1

Organism

Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) [Complete proteome] [HAMAP] EMBL AAW61468.1

Taxonomic identifier

290633 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconobacter › Gluconobacter oxydans

Protein attributes

Sequence length	517 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00378 SAAS SAAS025824
Catalytic activity	Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00378 Exonucleolytic cleavage in either 5'- to 3'-or 3'- to 5'-direction to yield nucleoside 5'-phosphates. SAAS SAAS025824
Subunit structure	Heterooligomer composed of large and small subunits By similarity. HAMAP-Rule MF_00378 SAAS SAAS025824
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00378 SAAS SAAS025824.
Sequence similarities	Belongs to the XseA family. HAMAP-Rule MF_00378

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00378 SAAS SAAS025824
Molecular function	Exonuclease HAMAP-Rule MF_00378 SAAS SAAS025824 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA catabolic process Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exodeoxyribonuclease VII complex Inferred from electronic annotation. Source: InterPro
Molecular_function	exodeoxyribonuclease VII activity Inferred from electronic annotation. Source: HAMAP nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5FQ78 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: C3089585B3419B43	FASTA	517	56,364
	10 20 30 40 50 60 MMESDGASIR GNVPQYSVSE ISGAIKRTLE SGFGRVRVRG EVTELKRYPS GHVYLSLKDE 70 80 90 100 110 120 GGKIAGVIWR GSVSRLGMAP ENGNEVIATG RVSAYGERSS YQLVIDRMEF AGEGALLANI 130 140 150 160 170 180 ERLRRKLLEE GLFEPERKKA IPFLPSLVGV ITSRSGAVLH DIITTISRRF PRDVLLWPVP 190 200 210 220 230 240 VQGEGAAAQI AAAIEGMSVR RPRTPDVLIV ARGGGSLEDL MAFNDERVLR AVANCPVPII 250 260 270 280 290 300 SAVGHETDTT LIDLVSDRRA PTPTAAAEMA VPLRSEMVAD MAHRNARLTG ALTRIIQTAR 310 320 330 340 350 360 AQLDQAAARL PDLPGLLDSA RMRLDDRGQR LDLALPSFVM RVRNRLDAPG MHLPSPELLI 370 380 390 400 410 420 GRSRARLQAL RLPAPELLVS RARARLTAPT THLPSPELLI ERRRAGLRLV SGELDTAWQR 430 440 450 460 470 480 SLQTFQLRTE RQRLSPDILR SAIRLQQARL QGLGSHLEAV SPRAILSRGY VLVQDVNGQP 490 500 510 VTSAEARPVA DRVVLSFADG DRGARLDSLS PQGDLGL

References

[1]

"Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans." Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U. Nat. Biotechnol. 23:195-200(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 621H EMBL AAW61468.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000009 Genomic DNA. Translation: AAW61468.1.
RefSeq	YP_192124.1. NC_006677.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	290633.GOX1729.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAW61468; AAW61468; GOX1729.
GeneID	3249469.
KEGG	gox:GOX1729.
PATRIC	32611334. VBIGluOxy81109_2006.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000229266.
KO	K03601.
OMA	HGSGHAY.
ProtClustDB	CLSK936469.
Enzyme and pathway databases
BioCyc	GOXY290633:GHB3-1736-MONOMER.
Family and domain databases
HAMAP	MF_00378. Exonuc_7_L.
InterPro	IPR003753. Exonuc_VII_L. IPR020579. Exonuc_VII_lsu_C. IPR025824. OB-fold_nuc-bd_dom. [Graphical view]
Pfam	PF02601. Exonuc_VII_L. 1 hit. PF13742. tRNA_anti_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00237. xseA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5FQ78_GLUOX

Accession

Primary (citable) accession number: Q5FQ78

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2005
Last sequence update:	March 1, 2005
Last modified:	May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)