Q5FPT6 (GLND_GLUOX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	GOX1872

Organism

Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) [Complete proteome] [HAMAP]

Taxonomic identifier

290633 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconobacter › Gluconobacter oxydans

Protein attributes

Sequence length	949 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 949	949	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_0000192735

Sequences

	Sequence		Length	Mass (Da)
	Q5FPT6 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: 79BEEE7485522A9B	FASTA	949	105,398
	10 20 30 40 50 60 MKETSFWGET PSLSFADDTD KPLSDRTASP PCDPASSLQT ALDTAAAQGQ TTRENVLSIL 70 80 90 100 110 120 RRHLGSGNAT VRREFEKRRM SGIDAARALA RQADDMVCAL AELAAQKHES PGETLCLCAT 130 140 150 160 170 180 GGYGAGLLAP FSDIDILFLI PGDPTPAMTA RIEFILYALW DLGLRVGHAT RSIAECVRDA 190 200 210 220 230 240 DSDLTIRTAL LDLRFLHGER GLARDLRCAL GADLQNDRLC EFVMGKIAER EQRHRRFGDN 250 260 270 280 290 300 PYMVEPNIKE GRGGLRDLQT LNWMGRAALG CAVSTPDRSG QPAEAPQTPS FASFGLLTDR 310 320 330 340 350 360 ESLRARRSWD FLWTVRLHLH YITGRAEERL TFDVQPVIGG RMGYATHGRQ RGVERFMRHY 370 380 390 400 410 420 FLTARDVMRL TSVLQPVVLM HLQDQTTGEP PKVVPGPEEF QTIAGRICPI EPVTFAAQPR 430 440 450 460 470 480 EMFRLLDCGR RHDLPLHPIA MQQIIRNERH AVTLRDDPET AKIFLDLLCE PSADETKAVP 490 500 510 520 530 540 FWLPILNETG LLGRLLPDWS RVVGQMQFDS YHIYTVDEHI VEAVRMMGQI EAGRMADEIP 550 560 570 580 590 600 LAYTLASDLR SRRALYVAVL LHDIGKGRGG DHSEIGADLA LTICPQLGLD PEETDTVSWL 610 620 630 640 650 660 VLHHLLLSQT AFTRDIDDPR TILDLADTIQ SPERLRLLLL LTIADMRAVS PKVWNAWKAT 670 680 690 700 710 720 LLRELFSRVA EVLEGGLAAT ERDSRVNHAR ELARDGLTGI LPESSIDRFL DLGYPSYWLG 730 740 750 760 770 780 FDTDTQMRHA RMVHDSDRYR SPVTVEAYPI PERGVTELTV LCADHPGLFS QIAGALAVSG 790 800 810 820 830 840 ASIVDARIHT LSDGMALDTF WVQDGEGCSF EEPHQLGRLN HLVEQALSGR LDIRKGIEDA 850 860 870 880 890 900 SHHSTSRRMR AIHVPPRVVI DNTASDRHTV IEVNGRDRPG LLHDVTSALS SASLQISSAH 910 920 930 940 ITTYGMRAVD VFYVRDLLGM KITDPVRLAR LRETLLASLT SAPVTTPAS

References

[1]

"Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans." Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U. Nat. Biotechnol. 23:195-200(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 621H.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000009 Genomic DNA. Translation: AAW61610.1.
RefSeq	YP_192266.1. NC_006677.1.
3D structure databases
ProteinModelPortal	Q5FPT6.
ModBase	Search...
Protein-protein interaction databases
STRING	290633.GOX1872.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAW61610; AAW61610; GOX1872.
GeneID	3250631.
KEGG	gox:GOX1872.
PATRIC	32611646. VBIGluOxy81109_2161.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261779.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05092.
Enzyme and pathway databases
BioCyc	GOXY290633:GHB3-1878-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_GLUOX

Accession

Primary (citable) accession number: Q5FPT6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
Last sequence update:	March 1, 2005
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program