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Q5FP94 (GLSA_GLUOX) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:GOX2066
OrganismGluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) [Complete proteome] [HAMAP]
Taxonomic identifier290633 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeGluconobacter

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Glutaminase HAMAP-Rule MF_00313
PRO_0000336027

Sites

Binding site641Substrate By similarity
Binding site1141Substrate By similarity
Binding site1611Substrate By similarity
Binding site1681Substrate By similarity
Binding site1921Substrate By similarity
Binding site2441Substrate By similarity
Binding site2621Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5FP94 [UniParc].

Last modified March 1, 2005. Version 1.
Checksum: 11F5C022D148E793

FASTA31834,315
        10         20         30         40         50         60 
MSTVASIIVS IAEEMRTASE RGTVANYIPP LARVDLNRFG MAVVGMDGET HTVGDAEVPF 

        70         80         90        100        110        120 
SVQSVSKVFS LSMALNAMGD ELWGRVRQEP SGSAFNSIVQ LENEHGIPRN PFINAGAIVI 

       130        140        150        160        170        180 
ADILVSRYGR ENAQTRLLEF LRPLVSDPSS IDIDTDVARQ ERETGFRNMA LANYMRTFGN 

       190        200        210        220        230        240 
IRNVVEDTLD FYFHQCALTM SCHQLAQVGT CLMTGGRNPL TGERIMSERN AQTILALMMM 

       250        260        270        280        290        300 
CGHYDGSGAF AIRVGLPGKS GVGGGILAIA PGVASIAVWS PGLNAQGNSL LGTRALERLV 

       310 
QHTGWSVFRA NPWVANPT 

« Hide

References

[1]"Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans."
Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U.
Nat. Biotechnol. 23:195-200(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 621H.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000009 Genomic DNA. Translation: AAW61802.1.
RefSeqYP_192458.1. NC_006677.1.

3D structure databases

ProteinModelPortalQ5FP94.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290633.GOX2066.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAW61802; AAW61802; GOX2066.
GeneID3248248.
KEGGgox:GOX2066.
PATRIC32612068. VBIGluOxy81109_2370.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycGOXY290633:GHB3-2064-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_GLUOX
AccessionPrimary (citable) accession number: Q5FP94
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 1, 2005
Last modified: February 19, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families