Q5FNM2 (Q5FNM2_GLUOX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Dihydrolipoyl dehydrogenase RuleBase RU003692
EC=1.8.1.4 RuleBase RU003692

Gene names

Ordered Locus Names:

GOX2292 EMBL AAW62025.1

Organism

Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) [Complete proteome] [HAMAP] EMBL AAW62025.1

Taxonomic identifier

290633 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodospirillales › Acetobacteraceae › Gluconobacter › Gluconobacter oxydans

Protein attributes

Sequence length	468 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH. RuleBase RU003692
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003692
Miscellaneous	The active site is a redox-active disulfide bond By similarity. RuleBase RU003692
Sequence similarities	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003691

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003691
Ligand	FAD RuleBase RU003691 Flavoprotein RuleBase RU003691 NAD RuleBase RU003692
Molecular function	Oxidoreductase RuleBase RU003691 EMBL AAW62025.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	dihydrolipoyl dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5FNM2 [UniParc]. Last modified March 1, 2005. Version 1. Checksum: 475199B0B0FC0B3C	FASTA	468	49,242
	10 20 30 40 50 60 MCDTFDLIVV GGGPGGYVAA LRASQLGMSV ALVESTHFGG VCLNWGCIPT KALLRSSEIH 70 80 90 100 110 120 HLLHELGTFG LSADNISFDL SKIVGRSRSI ARRMGGGIAH LLKKTKVTTF DGRAKLAGRS 130 140 150 160 170 180 GEAHQVAITK DGAAVATIKA PHVILATGAR GRQLPGLETD GTLIWGAREA MTPKELPKRL 190 200 210 220 230 240 LVIGSGAIGI EFASFYRNMG SEVTIAEVAD RILIAEDPEI SAAARKAFEK QGMKIITSAK 250 260 270 280 290 300 VGPLNKGENE VSTTIESPTG KVDLTVDRVI CAVGIVGNVE DLGLEGTKVQ VERTHIVTDG 310 320 330 340 350 360 FCRTGEPGIY AIGDVAGAPW LAHKASHEGI LCVEKIAGRS PQPLHPLNIP GCTYSRPQIA 370 380 390 400 410 420 SVGLSEEKAI AAGHKVKVGR FPFIANGKAV AMGETDGMVK TVFDATSGEL LGAHMIGAEV 430 440 450 460 TEMIQGYVIT RTGELTEAEL VETVFPHPTI SETMHEATLA AFDGPLHI

References

[1]

"Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans." Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F., Ehrenreich A., Gottschalk G., Deppenmeier U. Nat. Biotechnol. 23:195-200(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 621H EMBL AAW62025.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000009 Genomic DNA. Translation: AAW62025.1.
RefSeq	YP_192681.1. NC_006677.1.
3D structure databases
ProteinModelPortal	Q5FNM2.
ModBase	Search...
Protein-protein interaction databases
STRING	290633.GOX2292.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAW62025; AAW62025; GOX2292.
GeneID	3249911.
KEGG	gox:GOX2292.
PATRIC	32612550. VBIGluOxy81109_2608.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000276708.
KO	K00382.
OMA	CTAKIAG.
Enzyme and pathway databases
BioCyc	GOXY290633:GHB3-2293-MONOMER.
Family and domain databases
Gene3D	3.30.390.30. 1 hit.
InterPro	IPR016156. FAD/NAD-linked_Rdtase_dimer. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR006258. Lipoamide_DH. IPR004099. Pyr_nucl-diS_OxRdtase_dimer. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR012999. Pyr_OxRdtase_I_AS. IPR001327. Pyr_OxRdtase_NAD-bd_dom. [Graphical view]
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. PF02852. Pyr_redox_dim. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR.
SUPFAM	SSF55424. FAD/NAD-linked_reductase_dimer. 1 hit.
TIGRFAMs	TIGR01350. lipoamide_DH. 1 hit.
PROSITE	PS00076. PYRIDINE_REDOX_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5FNM2_GLUOX

Accession

Primary (citable) accession number: Q5FNM2

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2005
Last sequence update:	March 1, 2005
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)