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Q5FL65 (GLGA_LACAC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycogen synthase
EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:LBA0683
OrganismLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) [Complete proteome] [HAMAP]
Taxonomic identifier272621 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus ›

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476Glycogen synthase HAMAP-Rule MF_00484
PRO_0000230244

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5FL65 [UniParc].

Last modified March 1, 2005. Version 1.
Checksum: C77DE5FC9C7FBF9A

FASTA47654,822
        10         20         30         40         50         60 
MRVLFTGAEC APFFKTGGLG DVLGSLPNQL AKEGVDVGVV LPLYQDLPEK YRKNLKYQGN 

        70         80         90        100        110        120 
FIVPVGWRNQ YCGIFTLKLN GVNYFFIDNE YYFKRPGIYG YYDDGERYAY FQQAVIMMME 

       130        140        150        160        170        180 
RFDFIPDVLH CNDYHTAFIP FLLHEKWGFV DAYKGIKTIL TIHNLEFQGK YNAKTLPDFF 

       190        200        210        220        230        240 
GMNYDWFDSG IVRMDNDVNW MKTGILYADR VTTVSPSYAR EIQTVEFGQG LDAILRMCSH 

       250        260        270        280        290        300 
KLTGILNGID FEKYNPKTDP VIKKNYDVYH LHHKSKDKIA LQKELDLPIK PNIPLIGMVS 

       310        320        330        340        350        360 
RLTAQKGCQL LLDELDNILQ FNVQIVILGN GDPYYEHRLM EIAERYPDKL KVILAFDVKL 

       370        380        390        400        410        420 
AQRIYAGADS FLMPSAFEPC GLSQLIALRY GTLPIVHEIG GLADTVWVYD ETTNEGTGFG 

       430        440        450        460        470 
FKEFSGYQMV QAIKKMLALY QQKNNWLKIQ KIAMKSDFSW KNSADKYKWM YGELIG

« Hide

References

[1]"Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM."
Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L., McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S., Hamrick A., Cano R., Klaenhammer T.R.
Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700396 / NCK56 / N2 / NCFM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000033 Genomic DNA. Translation: AAV42559.1.
RefSeqYP_193590.1. NC_006814.3.

3D structure databases

ProteinModelPortalQ5FL65.
ModBaseSearch...

Protein-protein interaction databases

STRING272621.LBA0683.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV42559; AAV42559; LBA0683.
GeneID3251261.
KEGGlac:LBA0683.
PATRIC22196470. VBILacAci7974_0653.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMAADVIMVP.
ProtClustDBPRK00654.

Enzyme and pathway databases

UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_LACAC
AccessionPrimary (citable) accession number: Q5FL65
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: March 1, 2005
Last modified: May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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