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Q5FL04

- G6PI_LACAC

UniProt

Q5FL04 - G6PI_LACAC

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, LBA0752
Organism
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei287 – 2871Proton donor By similarity
Active sitei308 – 3081 By similarity
Active sitei422 – 4221 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:LBA0752
OrganismiLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Taxonomic identifieri272621 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000006381: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Glucose-6-phosphate isomeraseUniRule annotationPRO_0000180656Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272621.LBA0752.

Structurei

3D structure databases

ProteinModelPortaliQ5FL04.
SMRiQ5FL04. Positions 4-445.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiQVIFIGN.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FL04-1 [UniParc]FASTAAdd to Basket

« Hide

MSLIKFDSSK LTPFIHENEL SEMQAMVNAA NEELRDGTGA GSDFRGWLNL    50
PVDYDKEEFD RIKKAAKKIQ SDSDVLICIG IGGSYLGAQA AIEFLNSNFY 100
GKEDNGMPTV VFCGNSLSGS YLYDLIEWVG DKDFSINVIS KSGTTTEPSV 150
AFRIFKDKLI KKYGKEEAAK RIYATTDRQK GALKTEADAE GYEEFVVPDD 200
IGGRYSVLTA VGLLPIAASG ADIDELMKGA ADARADYTDT DLSKATPYQY 250
AAIRNILYRK GYTTEIVENY EPSLRMFGEW CKQLMGESEG KDQKGIWPSS 300
ANFTTDLHSL GQYIQEGLRN LFETVIRVEN PRHDVKIPGD EKNLDQLNFL 350
EGKSLNYVND RAYEGVVLAH TDGGVPVMTI NIPDQTAHTL GYMIYFFELA 400
IAISGYLNGI NPFNQPGVEA YKRNMFGLLN KPGYENLHDD LAKRL 445
Length:445
Mass (Da):49,507
Last modified:March 1, 2005 - v1
Checksum:i046A2A0567338400
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000033 Genomic DNA. Translation: AAV42620.1.
RefSeqiYP_193651.1. NC_006814.3.

Genome annotation databases

EnsemblBacteriaiAAV42620; AAV42620; LBA0752.
GeneIDi3252080.
KEGGilac:LBA0752.
PATRICi22196600. VBILacAci7974_0717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000033 Genomic DNA. Translation: AAV42620.1 .
RefSeqi YP_193651.1. NC_006814.3.

3D structure databases

ProteinModelPortali Q5FL04.
SMRi Q5FL04. Positions 4-445.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272621.LBA0752.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAV42620 ; AAV42620 ; LBA0752 .
GeneIDi 3252080.
KEGGi lac:LBA0752.
PATRICi 22196600. VBILacAci7974_0717.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi QVIFIGN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700396 / NCK56 / N2 / NCFM.

Entry informationi

Entry nameiG6PI_LACAC
AccessioniPrimary (citable) accession number: Q5FL04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 1, 2005
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi