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Q5FL04

- G6PI_LACAC

UniProt

Q5FL04 - G6PI_LACAC

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Mar 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei287 – 2871Proton donorUniRule annotation
    Active sitei308 – 3081UniRule annotation
    Active sitei422 – 4221UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:LBA0752
    OrganismiLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
    Taxonomic identifieri272621 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000006381: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 445445Glucose-6-phosphate isomerasePRO_0000180656Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272621.LBA0752.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5FL04.
    SMRiQ5FL04. Positions 4-445.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiQVIFIGN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5FL04-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLIKFDSSK LTPFIHENEL SEMQAMVNAA NEELRDGTGA GSDFRGWLNL    50
    PVDYDKEEFD RIKKAAKKIQ SDSDVLICIG IGGSYLGAQA AIEFLNSNFY 100
    GKEDNGMPTV VFCGNSLSGS YLYDLIEWVG DKDFSINVIS KSGTTTEPSV 150
    AFRIFKDKLI KKYGKEEAAK RIYATTDRQK GALKTEADAE GYEEFVVPDD 200
    IGGRYSVLTA VGLLPIAASG ADIDELMKGA ADARADYTDT DLSKATPYQY 250
    AAIRNILYRK GYTTEIVENY EPSLRMFGEW CKQLMGESEG KDQKGIWPSS 300
    ANFTTDLHSL GQYIQEGLRN LFETVIRVEN PRHDVKIPGD EKNLDQLNFL 350
    EGKSLNYVND RAYEGVVLAH TDGGVPVMTI NIPDQTAHTL GYMIYFFELA 400
    IAISGYLNGI NPFNQPGVEA YKRNMFGLLN KPGYENLHDD LAKRL 445
    Length:445
    Mass (Da):49,507
    Last modified:March 1, 2005 - v1
    Checksum:i046A2A0567338400
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000033 Genomic DNA. Translation: AAV42620.1.
    RefSeqiYP_193651.1. NC_006814.3.

    Genome annotation databases

    EnsemblBacteriaiAAV42620; AAV42620; LBA0752.
    GeneIDi3252080.
    KEGGilac:LBA0752.
    PATRICi22196600. VBILacAci7974_0717.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000033 Genomic DNA. Translation: AAV42620.1 .
    RefSeqi YP_193651.1. NC_006814.3.

    3D structure databases

    ProteinModelPortali Q5FL04.
    SMRi Q5FL04. Positions 4-445.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272621.LBA0752.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV42620 ; AAV42620 ; LBA0752 .
    GeneIDi 3252080.
    KEGGi lac:LBA0752.
    PATRICi 22196600. VBILacAci7974_0717.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi QVIFIGN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700396 / NCK56 / N2 / NCFM.

    Entry informationi

    Entry nameiG6PI_LACAC
    AccessioniPrimary (citable) accession number: Q5FL04
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2005
    Last sequence update: March 1, 2005
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3