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Q5FL04

- G6PI_LACAC

UniProt

Q5FL04 - G6PI_LACAC

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei287 – 2871Proton donorUniRule annotation
Active sitei308 – 3081UniRule annotation
Active sitei422 – 4221UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:LBA0752
OrganismiLactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Taxonomic identifieri272621 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000006381: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Glucose-6-phosphate isomerasePRO_0000180656Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272621.LBA0752.

Structurei

3D structure databases

ProteinModelPortaliQ5FL04.
SMRiQ5FL04. Positions 4-445.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiQVIFIGN.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5FL04 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLIKFDSSK LTPFIHENEL SEMQAMVNAA NEELRDGTGA GSDFRGWLNL
60 70 80 90 100
PVDYDKEEFD RIKKAAKKIQ SDSDVLICIG IGGSYLGAQA AIEFLNSNFY
110 120 130 140 150
GKEDNGMPTV VFCGNSLSGS YLYDLIEWVG DKDFSINVIS KSGTTTEPSV
160 170 180 190 200
AFRIFKDKLI KKYGKEEAAK RIYATTDRQK GALKTEADAE GYEEFVVPDD
210 220 230 240 250
IGGRYSVLTA VGLLPIAASG ADIDELMKGA ADARADYTDT DLSKATPYQY
260 270 280 290 300
AAIRNILYRK GYTTEIVENY EPSLRMFGEW CKQLMGESEG KDQKGIWPSS
310 320 330 340 350
ANFTTDLHSL GQYIQEGLRN LFETVIRVEN PRHDVKIPGD EKNLDQLNFL
360 370 380 390 400
EGKSLNYVND RAYEGVVLAH TDGGVPVMTI NIPDQTAHTL GYMIYFFELA
410 420 430 440
IAISGYLNGI NPFNQPGVEA YKRNMFGLLN KPGYENLHDD LAKRL
Length:445
Mass (Da):49,507
Last modified:March 1, 2005 - v1
Checksum:i046A2A0567338400
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000033 Genomic DNA. Translation: AAV42620.1.
RefSeqiYP_193651.1. NC_006814.3.

Genome annotation databases

EnsemblBacteriaiAAV42620; AAV42620; LBA0752.
GeneIDi3252080.
KEGGilac:LBA0752.
PATRICi22196600. VBILacAci7974_0717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000033 Genomic DNA. Translation: AAV42620.1 .
RefSeqi YP_193651.1. NC_006814.3.

3D structure databases

ProteinModelPortali Q5FL04.
SMRi Q5FL04. Positions 4-445.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272621.LBA0752.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAV42620 ; AAV42620 ; LBA0752 .
GeneIDi 3252080.
KEGGi lac:LBA0752.
PATRICi 22196600. VBILacAci7974_0717.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi QVIFIGN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700396 / NCK56 / N2 / NCFM.

Entry informationi

Entry nameiG6PI_LACAC
AccessioniPrimary (citable) accession number: Q5FL04
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: March 1, 2005
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3